STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MRPL15Mitochondrial ribosomal protein of the large subunit; Belongs to the ribonuclease III family. Mitochondrion- specific ribosomal protein mL57 subfamily. (253 aa)    
Predicted Functional Partners:
MRPL3
Mitochondrial ribosomal protein of the large subunit; located in close proximity to the polypeptide exit channel of the ribosome; mutations in human homolog MRPL44 cause childhood cardiomyopathy; human MRPL44 deficiency results in inefficient assembly of the mitochondrial ribosome, and in tissue-specific respiratory chain deficiency, manifesting as either Complex I+Complex IV or Complex IV deficiency, depending on a cell type; Belongs to the ribonuclease III family. Mitochondrion- specific ribosomal protein mL44 subfamily.
   
 
 0.980
MRPL31
Mitochondrial ribosomal protein of the large subunit.
   
 
 0.973
IMG1
Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome.
   
   0.971
MRPL20
Mitochondrial ribosomal protein of the large subunit.
   
 
 0.968
MRPL13
Mitochondrial ribosomal protein of the large subunit; not essential for mitochondrial translation.
   
 
 0.963
MRPL51
Mitochondrial ribosomal protein of the large subunit.
   
 
 0.959
MHR1
Mitochondrial ribosomal protein of the large subunit; also involved in homologous recombination in mitochondria; required for recombination-dependent mtDNA partitioning; involved in stimulation of mitochondrial DNA replication in response to oxidative stress.
   
 
 0.955
RSM26
Mitochondrial ribosomal protein of the small subunit.
   
 
 0.952
IMG2
Mitochondrial ribosomal protein of the large subunit; conserved in metazoa, with similarity to human mitochondrial ribosomal protein MRPL49.
   
 
 0.949
MRPL17
Mitochondrial ribosomal protein of the large subunit.
   
 
 0.949
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: ATCC 18824, Candida robusta, Mycoderma cerevisiae, NRRL Y-12632, S. cerevisiae, Saccharomyces capensis, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, yeast
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.