node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARP7 | NPL6 | YPR034W | YMR091C | Actin-related protein 7; Component of both the SWI/SNF and RSC chromatin remodeling complexes; actin-related protein involved in transcriptional regulation. | Chromatin structure-remodeling complex subunit RSC7; Component of the RSC chromatin remodeling complex; interacts with Rsc3p, Rsc30p, Ldb7p, and Htl1p to form a module important for a broad range of RSC functions. | 0.999 |
ARP7 | RSC2 | YPR034W | YLR357W | Actin-related protein 7; Component of both the SWI/SNF and RSC chromatin remodeling complexes; actin-related protein involved in transcriptional regulation. | Chromatin structure-remodeling complex subunit RSC2; Component of the RSC chromatin remodeling complex; required for expression of mid-late sporulation-specific genes; involved in telomere maintenance; RSC2 has a paralog, RSC1, that arose from the whole genome duplication; Belongs to the RSC1 family. | 0.999 |
ARP7 | RSC3 | YPR034W | YDR303C | Actin-related protein 7; Component of both the SWI/SNF and RSC chromatin remodeling complexes; actin-related protein involved in transcriptional regulation. | Chromatin structure-remodeling complex protein RSC3; Component of the RSC chromatin remodeling complex; essential gene required for maintenance of proper ploidy and regulation of ribosomal protein genes and the cell wall/stress response; RSC3 has a paralog, RSC30, that arose from the whole genome duplication. | 0.999 |
ARP7 | RSC4 | YPR034W | YKR008W | Actin-related protein 7; Component of both the SWI/SNF and RSC chromatin remodeling complexes; actin-related protein involved in transcriptional regulation. | Chromatin structure-remodeling complex subunit RSC4; Component of the RSC chromatin remodeling complex; found in close proximity to nucleosomal DNA; displaced from the surface of nucleosomal DNA after chromatin remodeling; acetylated (K25) by Gcn5p, altering replication stress tolerance; contains tandem bromodomains that recognize histone H3 acetylated on K14 (H3K14ac) by Gcn5p. | 0.999 |
ARP7 | RSC58 | YPR034W | YLR033W | Actin-related protein 7; Component of both the SWI/SNF and RSC chromatin remodeling complexes; actin-related protein involved in transcriptional regulation. | Chromatin structure-remodeling complex protein RSC58; Component of the RSC chromatin remodeling complex; RSC functions in transcriptional regulation and elongation, chromosome stability, and establishing sister chromatid cohesion; involved in telomere maintenance. | 0.999 |
ARP7 | RSC6 | YPR034W | YCR052W | Actin-related protein 7; Component of both the SWI/SNF and RSC chromatin remodeling complexes; actin-related protein involved in transcriptional regulation. | Component of the RSC chromatin remodeling complex; essential for mitotic growth; RSC6 has a paralog, SNF12, that arose from the whole genome duplication. | 0.999 |
ARP7 | RSC8 | YPR034W | YFR037C | Actin-related protein 7; Component of both the SWI/SNF and RSC chromatin remodeling complexes; actin-related protein involved in transcriptional regulation. | Chromatin structure-remodeling complex protein RSC8; Component of the RSC chromatin remodeling complex; essential for viability and mitotic growth; homolog of SWI/SNF subunit Swi3p, but unlike Swi3p, does not activate transcription of reporters. | 0.999 |
ARP7 | RSC9 | YPR034W | YML127W | Actin-related protein 7; Component of both the SWI/SNF and RSC chromatin remodeling complexes; actin-related protein involved in transcriptional regulation. | Chromatin structure-remodeling complex subunit RSC9; Component of the RSC chromatin remodeling complex; DNA-binding protein involved in the synthesis of rRNA and in transcriptional repression and activation of genes regulated by the Target of Rapamycin (TOR) pathway; Belongs to the RSC9 family. | 0.999 |
ARP7 | SFH1 | YPR034W | YLR321C | Actin-related protein 7; Component of both the SWI/SNF and RSC chromatin remodeling complexes; actin-related protein involved in transcriptional regulation. | Chromatin structure-remodeling complex subunit SFH1; Component of the RSC chromatin remodeling complex; essential gene required for cell cycle progression and maintenance of proper ploidy; phosphorylated in the G1 phase of the cell cycle; Snf5p paralog; hSNF5 tumor suppressor ortholog. | 0.998 |
ARP7 | STH1 | YPR034W | YIL126W | Actin-related protein 7; Component of both the SWI/SNF and RSC chromatin remodeling complexes; actin-related protein involved in transcriptional regulation. | Nuclear protein STH1/NPS1; ATPase component of the RSC chromatin remodeling complex; required for expression of early meiotic genes; promotes base excision repair in chromatin; essential helicase-related protein homologous to Snf2p. | 0.999 |
NPL6 | ARP7 | YMR091C | YPR034W | Chromatin structure-remodeling complex subunit RSC7; Component of the RSC chromatin remodeling complex; interacts with Rsc3p, Rsc30p, Ldb7p, and Htl1p to form a module important for a broad range of RSC functions. | Actin-related protein 7; Component of both the SWI/SNF and RSC chromatin remodeling complexes; actin-related protein involved in transcriptional regulation. | 0.999 |
NPL6 | RSC2 | YMR091C | YLR357W | Chromatin structure-remodeling complex subunit RSC7; Component of the RSC chromatin remodeling complex; interacts with Rsc3p, Rsc30p, Ldb7p, and Htl1p to form a module important for a broad range of RSC functions. | Chromatin structure-remodeling complex subunit RSC2; Component of the RSC chromatin remodeling complex; required for expression of mid-late sporulation-specific genes; involved in telomere maintenance; RSC2 has a paralog, RSC1, that arose from the whole genome duplication; Belongs to the RSC1 family. | 0.999 |
NPL6 | RSC3 | YMR091C | YDR303C | Chromatin structure-remodeling complex subunit RSC7; Component of the RSC chromatin remodeling complex; interacts with Rsc3p, Rsc30p, Ldb7p, and Htl1p to form a module important for a broad range of RSC functions. | Chromatin structure-remodeling complex protein RSC3; Component of the RSC chromatin remodeling complex; essential gene required for maintenance of proper ploidy and regulation of ribosomal protein genes and the cell wall/stress response; RSC3 has a paralog, RSC30, that arose from the whole genome duplication. | 0.999 |
NPL6 | RSC4 | YMR091C | YKR008W | Chromatin structure-remodeling complex subunit RSC7; Component of the RSC chromatin remodeling complex; interacts with Rsc3p, Rsc30p, Ldb7p, and Htl1p to form a module important for a broad range of RSC functions. | Chromatin structure-remodeling complex subunit RSC4; Component of the RSC chromatin remodeling complex; found in close proximity to nucleosomal DNA; displaced from the surface of nucleosomal DNA after chromatin remodeling; acetylated (K25) by Gcn5p, altering replication stress tolerance; contains tandem bromodomains that recognize histone H3 acetylated on K14 (H3K14ac) by Gcn5p. | 0.999 |
NPL6 | RSC58 | YMR091C | YLR033W | Chromatin structure-remodeling complex subunit RSC7; Component of the RSC chromatin remodeling complex; interacts with Rsc3p, Rsc30p, Ldb7p, and Htl1p to form a module important for a broad range of RSC functions. | Chromatin structure-remodeling complex protein RSC58; Component of the RSC chromatin remodeling complex; RSC functions in transcriptional regulation and elongation, chromosome stability, and establishing sister chromatid cohesion; involved in telomere maintenance. | 0.999 |
NPL6 | RSC6 | YMR091C | YCR052W | Chromatin structure-remodeling complex subunit RSC7; Component of the RSC chromatin remodeling complex; interacts with Rsc3p, Rsc30p, Ldb7p, and Htl1p to form a module important for a broad range of RSC functions. | Component of the RSC chromatin remodeling complex; essential for mitotic growth; RSC6 has a paralog, SNF12, that arose from the whole genome duplication. | 0.999 |
NPL6 | RSC8 | YMR091C | YFR037C | Chromatin structure-remodeling complex subunit RSC7; Component of the RSC chromatin remodeling complex; interacts with Rsc3p, Rsc30p, Ldb7p, and Htl1p to form a module important for a broad range of RSC functions. | Chromatin structure-remodeling complex protein RSC8; Component of the RSC chromatin remodeling complex; essential for viability and mitotic growth; homolog of SWI/SNF subunit Swi3p, but unlike Swi3p, does not activate transcription of reporters. | 0.999 |
NPL6 | RSC9 | YMR091C | YML127W | Chromatin structure-remodeling complex subunit RSC7; Component of the RSC chromatin remodeling complex; interacts with Rsc3p, Rsc30p, Ldb7p, and Htl1p to form a module important for a broad range of RSC functions. | Chromatin structure-remodeling complex subunit RSC9; Component of the RSC chromatin remodeling complex; DNA-binding protein involved in the synthesis of rRNA and in transcriptional repression and activation of genes regulated by the Target of Rapamycin (TOR) pathway; Belongs to the RSC9 family. | 0.999 |
NPL6 | SFH1 | YMR091C | YLR321C | Chromatin structure-remodeling complex subunit RSC7; Component of the RSC chromatin remodeling complex; interacts with Rsc3p, Rsc30p, Ldb7p, and Htl1p to form a module important for a broad range of RSC functions. | Chromatin structure-remodeling complex subunit SFH1; Component of the RSC chromatin remodeling complex; essential gene required for cell cycle progression and maintenance of proper ploidy; phosphorylated in the G1 phase of the cell cycle; Snf5p paralog; hSNF5 tumor suppressor ortholog. | 0.998 |
NPL6 | STH1 | YMR091C | YIL126W | Chromatin structure-remodeling complex subunit RSC7; Component of the RSC chromatin remodeling complex; interacts with Rsc3p, Rsc30p, Ldb7p, and Htl1p to form a module important for a broad range of RSC functions. | Nuclear protein STH1/NPS1; ATPase component of the RSC chromatin remodeling complex; required for expression of early meiotic genes; promotes base excision repair in chromatin; essential helicase-related protein homologous to Snf2p. | 0.999 |