node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DHR2 | DIP2 | YKL078W | YLR129W | Predominantly nucleolar DEAH-box ATP-dependent RNA helicase; required for 18S rRNA synthesis; Belongs to the DEAD box helicase family. DEAH subfamily. | Nucleolar protein; specifically associated with the U3 snoRNA, part of the large ribonucleoprotein complex known as the small subunit (SSU) processome, required for 18S rRNA biogenesis, part of the active pre-rRNA processing complex. | 0.854 |
DHR2 | FAL1 | YKL078W | YDR021W | Predominantly nucleolar DEAH-box ATP-dependent RNA helicase; required for 18S rRNA synthesis; Belongs to the DEAD box helicase family. DEAH subfamily. | ATP-dependent RNA helicase FAL1; Nucleolar protein required for maturation of 18S rRNA; member of the eIF4A subfamily of DEAD-box ATP-dependent RNA helicases; 18S rRNA biogenesis defect of the null mutant is functionally complemented by human EIF4A3; Belongs to the DEAD box helicase family. DDX48/FAL1 subfamily. | 0.999 |
DHR2 | HCA4 | YKL078W | YJL033W | Predominantly nucleolar DEAH-box ATP-dependent RNA helicase; required for 18S rRNA synthesis; Belongs to the DEAD box helicase family. DEAH subfamily. | DEAD box RNA helicase; component of the SSU; interacts with Bfr2p and Enp2p; high-copy number suppression of a U14 snoRNA processing mutant suggests an involvement in 18S rRNA synthesis; Belongs to the DEAD box helicase family. DDX10/DBP4 subfamily. | 0.952 |
DHR2 | KRE33 | YKL078W | YNL132W | Predominantly nucleolar DEAH-box ATP-dependent RNA helicase; required for 18S rRNA synthesis; Belongs to the DEAD box helicase family. DEAH subfamily. | RNA cytidine acetyltransferase; Protein required for biogenesis of the small ribosomal subunit; heterozygous mutant shows haploinsufficiency in K1 killer toxin resistance; essential gene; NAT10, the human homolog, implicated in several types of cancer and premature aging. | 0.792 |
DHR2 | KRR1 | YKL078W | YCL059C | Predominantly nucleolar DEAH-box ATP-dependent RNA helicase; required for 18S rRNA synthesis; Belongs to the DEAD box helicase family. DEAH subfamily. | KRR1 small subunit processome component; Nucleolar protein required for rRNA synthesis and ribosomal assembly; required for the synthesis of 18S rRNA and for the assembly of 40S ribosomal subunit; essential gene; Belongs to the KRR1 family. | 0.999 |
DHR2 | LCP5 | YKL078W | YER127W | Predominantly nucleolar DEAH-box ATP-dependent RNA helicase; required for 18S rRNA synthesis; Belongs to the DEAD box helicase family. DEAH subfamily. | U3 small nucleolar ribonucleoprotein protein LCP5; Essential protein involved in maturation of 18S rRNA; depletion leads to inhibited pre-rRNA processing and reduced polysome levels; localizes primarily to the nucleolus. | 0.998 |
DHR2 | SAS10 | YKL078W | YDL153C | Predominantly nucleolar DEAH-box ATP-dependent RNA helicase; required for 18S rRNA synthesis; Belongs to the DEAD box helicase family. DEAH subfamily. | Something about silencing protein 10; Subunit of U3-containing Small Subunit (SSU) processome complex; involved in production of 18S rRNA and assembly of small ribosomal subunit; disrupts silencing when overproduced; mutant has increased aneuploidy tolerance; essential gene. | 0.999 |
DHR2 | SGD1 | YKL078W | YLR336C | Predominantly nucleolar DEAH-box ATP-dependent RNA helicase; required for 18S rRNA synthesis; Belongs to the DEAD box helicase family. DEAH subfamily. | Suppressor of glycerol defect protein 1; Essential nuclear protein; required for biogenesis of the small ribosomal subunit; has a possible role in the osmoregulatory glycerol response; putative homolog of human NOM1 which is implicated in acute myeloid leukemia. | 0.997 |
DHR2 | UTP6 | YKL078W | YDR449C | Predominantly nucleolar DEAH-box ATP-dependent RNA helicase; required for 18S rRNA synthesis; Belongs to the DEAD box helicase family. DEAH subfamily. | Nucleolar protein; component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA. | 0.998 |
DIP2 | DHR2 | YLR129W | YKL078W | Nucleolar protein; specifically associated with the U3 snoRNA, part of the large ribonucleoprotein complex known as the small subunit (SSU) processome, required for 18S rRNA biogenesis, part of the active pre-rRNA processing complex. | Predominantly nucleolar DEAH-box ATP-dependent RNA helicase; required for 18S rRNA synthesis; Belongs to the DEAD box helicase family. DEAH subfamily. | 0.854 |
DIP2 | FAL1 | YLR129W | YDR021W | Nucleolar protein; specifically associated with the U3 snoRNA, part of the large ribonucleoprotein complex known as the small subunit (SSU) processome, required for 18S rRNA biogenesis, part of the active pre-rRNA processing complex. | ATP-dependent RNA helicase FAL1; Nucleolar protein required for maturation of 18S rRNA; member of the eIF4A subfamily of DEAD-box ATP-dependent RNA helicases; 18S rRNA biogenesis defect of the null mutant is functionally complemented by human EIF4A3; Belongs to the DEAD box helicase family. DDX48/FAL1 subfamily. | 0.646 |
DIP2 | HCA4 | YLR129W | YJL033W | Nucleolar protein; specifically associated with the U3 snoRNA, part of the large ribonucleoprotein complex known as the small subunit (SSU) processome, required for 18S rRNA biogenesis, part of the active pre-rRNA processing complex. | DEAD box RNA helicase; component of the SSU; interacts with Bfr2p and Enp2p; high-copy number suppression of a U14 snoRNA processing mutant suggests an involvement in 18S rRNA synthesis; Belongs to the DEAD box helicase family. DDX10/DBP4 subfamily. | 0.948 |
DIP2 | KRE33 | YLR129W | YNL132W | Nucleolar protein; specifically associated with the U3 snoRNA, part of the large ribonucleoprotein complex known as the small subunit (SSU) processome, required for 18S rRNA biogenesis, part of the active pre-rRNA processing complex. | RNA cytidine acetyltransferase; Protein required for biogenesis of the small ribosomal subunit; heterozygous mutant shows haploinsufficiency in K1 killer toxin resistance; essential gene; NAT10, the human homolog, implicated in several types of cancer and premature aging. | 0.999 |
DIP2 | KRR1 | YLR129W | YCL059C | Nucleolar protein; specifically associated with the U3 snoRNA, part of the large ribonucleoprotein complex known as the small subunit (SSU) processome, required for 18S rRNA biogenesis, part of the active pre-rRNA processing complex. | KRR1 small subunit processome component; Nucleolar protein required for rRNA synthesis and ribosomal assembly; required for the synthesis of 18S rRNA and for the assembly of 40S ribosomal subunit; essential gene; Belongs to the KRR1 family. | 0.999 |
DIP2 | LCP5 | YLR129W | YER127W | Nucleolar protein; specifically associated with the U3 snoRNA, part of the large ribonucleoprotein complex known as the small subunit (SSU) processome, required for 18S rRNA biogenesis, part of the active pre-rRNA processing complex. | U3 small nucleolar ribonucleoprotein protein LCP5; Essential protein involved in maturation of 18S rRNA; depletion leads to inhibited pre-rRNA processing and reduced polysome levels; localizes primarily to the nucleolus. | 0.998 |
DIP2 | RRP36 | YLR129W | YOR287C | Nucleolar protein; specifically associated with the U3 snoRNA, part of the large ribonucleoprotein complex known as the small subunit (SSU) processome, required for 18S rRNA biogenesis, part of the active pre-rRNA processing complex. | rRNA biogenesis protein RRP36; Component of 90S preribosomes; involved in early cleavages of the 35S pre-rRNA and in production of the 40S ribosomal subunit; Belongs to the RRP36 family. | 0.936 |
DIP2 | SAS10 | YLR129W | YDL153C | Nucleolar protein; specifically associated with the U3 snoRNA, part of the large ribonucleoprotein complex known as the small subunit (SSU) processome, required for 18S rRNA biogenesis, part of the active pre-rRNA processing complex. | Something about silencing protein 10; Subunit of U3-containing Small Subunit (SSU) processome complex; involved in production of 18S rRNA and assembly of small ribosomal subunit; disrupts silencing when overproduced; mutant has increased aneuploidy tolerance; essential gene. | 0.999 |
DIP2 | SGD1 | YLR129W | YLR336C | Nucleolar protein; specifically associated with the U3 snoRNA, part of the large ribonucleoprotein complex known as the small subunit (SSU) processome, required for 18S rRNA biogenesis, part of the active pre-rRNA processing complex. | Suppressor of glycerol defect protein 1; Essential nuclear protein; required for biogenesis of the small ribosomal subunit; has a possible role in the osmoregulatory glycerol response; putative homolog of human NOM1 which is implicated in acute myeloid leukemia. | 0.998 |
DIP2 | UTP6 | YLR129W | YDR449C | Nucleolar protein; specifically associated with the U3 snoRNA, part of the large ribonucleoprotein complex known as the small subunit (SSU) processome, required for 18S rRNA biogenesis, part of the active pre-rRNA processing complex. | Nucleolar protein; component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA. | 0.999 |
FAL1 | DHR2 | YDR021W | YKL078W | ATP-dependent RNA helicase FAL1; Nucleolar protein required for maturation of 18S rRNA; member of the eIF4A subfamily of DEAD-box ATP-dependent RNA helicases; 18S rRNA biogenesis defect of the null mutant is functionally complemented by human EIF4A3; Belongs to the DEAD box helicase family. DDX48/FAL1 subfamily. | Predominantly nucleolar DEAH-box ATP-dependent RNA helicase; required for 18S rRNA synthesis; Belongs to the DEAD box helicase family. DEAH subfamily. | 0.999 |