node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DCV1 | NAT2 | YFR012W | YGR147C | Protein of unknown function; deletion mutant shows strong genetic interaction with cdc28-as1 mutant in the presence of 1-NM-PP1; DCV1 has a paralog, YOL019W, that arose from the whole genome duplication. | Putative N-terminal acetyltransferase 2; Protein of unknown function; has an apparent role in acetylation of N-terminal methionine residues. | 0.839 |
DCV1 | SBE22 | YFR012W | YHR103W | Protein of unknown function; deletion mutant shows strong genetic interaction with cdc28-as1 mutant in the presence of 1-NM-PP1; DCV1 has a paralog, YOL019W, that arose from the whole genome duplication. | Protein involved in bud growth; involved in the transport of cell wall components from the Golgi to the cell surface; similar in structure and functionally redundant with Sbe2p; SBE22 has a paralog, SBE2, that arose from the whole genome duplication. | 0.800 |
DCV1 | SLP1 | YFR012W | YOR154W | Protein of unknown function; deletion mutant shows strong genetic interaction with cdc28-as1 mutant in the presence of 1-NM-PP1; DCV1 has a paralog, YOL019W, that arose from the whole genome duplication. | Uncharacterized protein SLP1; Glycosylated integral ER membrane protein of unknown function; forms an ER-membrane associated protein complex with Emp65p; member of the SUN-like family of proteins; genetic interactions suggest a role in folding of ER membrane proteins; required for nuclear envelope localization of Mps3p. | 0.791 |
DCV1 | SPO77 | YFR012W | YLR341W | Protein of unknown function; deletion mutant shows strong genetic interaction with cdc28-as1 mutant in the presence of 1-NM-PP1; DCV1 has a paralog, YOL019W, that arose from the whole genome duplication. | Sporulation-specific protein 77; Meiosis-specific protein of unknown function; required for spore wall formation during sporulation and for timely prospore membrane closure along with SPS1; required with Sps1p for phosphorylation and turnover of Ssp1p; dispensable for both nuclear divisions during meiosis. | 0.838 |
DCV1 | YFR012W-A | YFR012W | YFR012W-A | Protein of unknown function; deletion mutant shows strong genetic interaction with cdc28-as1 mutant in the presence of 1-NM-PP1; DCV1 has a paralog, YOL019W, that arose from the whole genome duplication. | Uncharacterized protein YFR012W-A; Putative protein of unknown function; identified by homology. | 0.915 |
DCV1 | YGR146C-A | YFR012W | YGR146C-A | Protein of unknown function; deletion mutant shows strong genetic interaction with cdc28-as1 mutant in the presence of 1-NM-PP1; DCV1 has a paralog, YOL019W, that arose from the whole genome duplication. | Uncharacterized protein YGR146C-A; Putative protein of unknown function. | 0.903 |
MLH2 | SPO74 | YLR035C | YGL170C | Protein involved in mismatch repair and meiotic recombination; only certain frameshift intermediates are mismatch repair substrates; forms a complex with Mlh1p. | Sporulation-specific protein 74; Component of the meiotic outer plaque of the spindle pole body; involved in modifying the meiotic outer plaque that is required prior to prospore membrane formation. | 0.754 |
MLH2 | SPO77 | YLR035C | YLR341W | Protein involved in mismatch repair and meiotic recombination; only certain frameshift intermediates are mismatch repair substrates; forms a complex with Mlh1p. | Sporulation-specific protein 77; Meiosis-specific protein of unknown function; required for spore wall formation during sporulation and for timely prospore membrane closure along with SPS1; required with Sps1p for phosphorylation and turnover of Ssp1p; dispensable for both nuclear divisions during meiosis. | 0.537 |
NAT2 | DCV1 | YGR147C | YFR012W | Putative N-terminal acetyltransferase 2; Protein of unknown function; has an apparent role in acetylation of N-terminal methionine residues. | Protein of unknown function; deletion mutant shows strong genetic interaction with cdc28-as1 mutant in the presence of 1-NM-PP1; DCV1 has a paralog, YOL019W, that arose from the whole genome duplication. | 0.839 |
NAT2 | SBE22 | YGR147C | YHR103W | Putative N-terminal acetyltransferase 2; Protein of unknown function; has an apparent role in acetylation of N-terminal methionine residues. | Protein involved in bud growth; involved in the transport of cell wall components from the Golgi to the cell surface; similar in structure and functionally redundant with Sbe2p; SBE22 has a paralog, SBE2, that arose from the whole genome duplication. | 0.696 |
NAT2 | SLP1 | YGR147C | YOR154W | Putative N-terminal acetyltransferase 2; Protein of unknown function; has an apparent role in acetylation of N-terminal methionine residues. | Uncharacterized protein SLP1; Glycosylated integral ER membrane protein of unknown function; forms an ER-membrane associated protein complex with Emp65p; member of the SUN-like family of proteins; genetic interactions suggest a role in folding of ER membrane proteins; required for nuclear envelope localization of Mps3p. | 0.635 |
NAT2 | SPO77 | YGR147C | YLR341W | Putative N-terminal acetyltransferase 2; Protein of unknown function; has an apparent role in acetylation of N-terminal methionine residues. | Sporulation-specific protein 77; Meiosis-specific protein of unknown function; required for spore wall formation during sporulation and for timely prospore membrane closure along with SPS1; required with Sps1p for phosphorylation and turnover of Ssp1p; dispensable for both nuclear divisions during meiosis. | 0.755 |
NAT2 | YFR012W-A | YGR147C | YFR012W-A | Putative N-terminal acetyltransferase 2; Protein of unknown function; has an apparent role in acetylation of N-terminal methionine residues. | Uncharacterized protein YFR012W-A; Putative protein of unknown function; identified by homology. | 0.839 |
NAT2 | YGR146C-A | YGR147C | YGR146C-A | Putative N-terminal acetyltransferase 2; Protein of unknown function; has an apparent role in acetylation of N-terminal methionine residues. | Uncharacterized protein YGR146C-A; Putative protein of unknown function. | 0.832 |
RRT12 | SMA2 | YCR045C | YML066C | Subtilase-type proteinase RRT12; Probable subtilisin-family protease; role in formation of the dityrosine layer of spore walls; localizes to the spore wall and also the nuclear envelope and ER region in mature spores. | Meiosis-specific prospore membrane protein; required to produce bending force necessary for proper assembly of the prospore membrane during sporulation; Belongs to the SMA2 family. | 0.726 |
RRT12 | SPO77 | YCR045C | YLR341W | Subtilase-type proteinase RRT12; Probable subtilisin-family protease; role in formation of the dityrosine layer of spore walls; localizes to the spore wall and also the nuclear envelope and ER region in mature spores. | Sporulation-specific protein 77; Meiosis-specific protein of unknown function; required for spore wall formation during sporulation and for timely prospore membrane closure along with SPS1; required with Sps1p for phosphorylation and turnover of Ssp1p; dispensable for both nuclear divisions during meiosis. | 0.554 |
SBE22 | DCV1 | YHR103W | YFR012W | Protein involved in bud growth; involved in the transport of cell wall components from the Golgi to the cell surface; similar in structure and functionally redundant with Sbe2p; SBE22 has a paralog, SBE2, that arose from the whole genome duplication. | Protein of unknown function; deletion mutant shows strong genetic interaction with cdc28-as1 mutant in the presence of 1-NM-PP1; DCV1 has a paralog, YOL019W, that arose from the whole genome duplication. | 0.800 |
SBE22 | NAT2 | YHR103W | YGR147C | Protein involved in bud growth; involved in the transport of cell wall components from the Golgi to the cell surface; similar in structure and functionally redundant with Sbe2p; SBE22 has a paralog, SBE2, that arose from the whole genome duplication. | Putative N-terminal acetyltransferase 2; Protein of unknown function; has an apparent role in acetylation of N-terminal methionine residues. | 0.696 |
SBE22 | SLP1 | YHR103W | YOR154W | Protein involved in bud growth; involved in the transport of cell wall components from the Golgi to the cell surface; similar in structure and functionally redundant with Sbe2p; SBE22 has a paralog, SBE2, that arose from the whole genome duplication. | Uncharacterized protein SLP1; Glycosylated integral ER membrane protein of unknown function; forms an ER-membrane associated protein complex with Emp65p; member of the SUN-like family of proteins; genetic interactions suggest a role in folding of ER membrane proteins; required for nuclear envelope localization of Mps3p. | 0.542 |
SBE22 | SPO77 | YHR103W | YLR341W | Protein involved in bud growth; involved in the transport of cell wall components from the Golgi to the cell surface; similar in structure and functionally redundant with Sbe2p; SBE22 has a paralog, SBE2, that arose from the whole genome duplication. | Sporulation-specific protein 77; Meiosis-specific protein of unknown function; required for spore wall formation during sporulation and for timely prospore membrane closure along with SPS1; required with Sps1p for phosphorylation and turnover of Ssp1p; dispensable for both nuclear divisions during meiosis. | 0.609 |