| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CKA2 | LCB3 | YOR061W | YJL134W | Alpha' catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching. | Long-chain base-1-phosphate phosphatase; specific for dihydrosphingosine-1-phosphate, regulates ceramide and long-chain base phosphates levels, involved in incorporation of exogenous long chain bases in sphingolipids; LCB3 has a paralog, YSR3, that arose from the whole genome duplication. | 0.861 |
| CKA2 | YHR131C | YOR061W | YHR131C | Alpha' catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching. | PH domain-containing protein YHR131C; Putative protein of unknown function; GFP-fusion protein localizes to the cytoplasm; overexpression causes cell cycle delay or arrest; contains a PH domain and binds phosphatidylinositols and other lipids in a large-scale study; YHR131C has a paralog, YNL144C, that arose from the whole genome duplication. | 0.954 |
| CKA2 | YLR407W | YOR061W | YLR407W | Alpha' catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching. | Uncharacterized protein YLR407W; Putative protein of unknown function; null mutant displays elongated buds and a large fraction of budded cells have only one nucleus. | 0.992 |
| LCB3 | CKA2 | YJL134W | YOR061W | Long-chain base-1-phosphate phosphatase; specific for dihydrosphingosine-1-phosphate, regulates ceramide and long-chain base phosphates levels, involved in incorporation of exogenous long chain bases in sphingolipids; LCB3 has a paralog, YSR3, that arose from the whole genome duplication. | Alpha' catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching. | 0.861 |
| LCB3 | YLR407W | YJL134W | YLR407W | Long-chain base-1-phosphate phosphatase; specific for dihydrosphingosine-1-phosphate, regulates ceramide and long-chain base phosphates levels, involved in incorporation of exogenous long chain bases in sphingolipids; LCB3 has a paralog, YSR3, that arose from the whole genome duplication. | Uncharacterized protein YLR407W; Putative protein of unknown function; null mutant displays elongated buds and a large fraction of budded cells have only one nucleus. | 0.654 |
| PKC1 | YLR407W | YBL105C | YLR407W | Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC). | Uncharacterized protein YLR407W; Putative protein of unknown function; null mutant displays elongated buds and a large fraction of budded cells have only one nucleus. | 0.947 |
| RXT3 | YLR407W | YDL076C | YLR407W | Transcriptional regulatory protein RXT3; Component of the Rpd3L histone deacetylase complex; involved in histone deacetylation; protein abundance increases in response to DNA replication stress; Belongs to the RXT3 family. | Uncharacterized protein YLR407W; Putative protein of unknown function; null mutant displays elongated buds and a large fraction of budded cells have only one nucleus. | 0.740 |
| YDL176W | YHR131C | YDL176W | YHR131C | Uncharacterized protein YDL176W; Protein of unknown function; predicted by computational methods to be involved in fructose-1,6-bisphosphatase (Fbp1p) degradation; interacts with components of the GID complex; YDL176W is not an essential gene. | PH domain-containing protein YHR131C; Putative protein of unknown function; GFP-fusion protein localizes to the cytoplasm; overexpression causes cell cycle delay or arrest; contains a PH domain and binds phosphatidylinositols and other lipids in a large-scale study; YHR131C has a paralog, YNL144C, that arose from the whole genome duplication. | 0.600 |
| YDL176W | YJR011C | YDL176W | YJR011C | Uncharacterized protein YDL176W; Protein of unknown function; predicted by computational methods to be involved in fructose-1,6-bisphosphatase (Fbp1p) degradation; interacts with components of the GID complex; YDL176W is not an essential gene. | Uncharacterized protein YJR011C; Putative protein of unknown function; GFP-fusion protein expression is induced in response to the DNA-damaging agent MMS. | 0.660 |
| YDL176W | YLR407W | YDL176W | YLR407W | Uncharacterized protein YDL176W; Protein of unknown function; predicted by computational methods to be involved in fructose-1,6-bisphosphatase (Fbp1p) degradation; interacts with components of the GID complex; YDL176W is not an essential gene. | Uncharacterized protein YLR407W; Putative protein of unknown function; null mutant displays elongated buds and a large fraction of budded cells have only one nucleus. | 0.677 |
| YHR131C | CKA2 | YHR131C | YOR061W | PH domain-containing protein YHR131C; Putative protein of unknown function; GFP-fusion protein localizes to the cytoplasm; overexpression causes cell cycle delay or arrest; contains a PH domain and binds phosphatidylinositols and other lipids in a large-scale study; YHR131C has a paralog, YNL144C, that arose from the whole genome duplication. | Alpha' catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching. | 0.954 |
| YHR131C | YDL176W | YHR131C | YDL176W | PH domain-containing protein YHR131C; Putative protein of unknown function; GFP-fusion protein localizes to the cytoplasm; overexpression causes cell cycle delay or arrest; contains a PH domain and binds phosphatidylinositols and other lipids in a large-scale study; YHR131C has a paralog, YNL144C, that arose from the whole genome duplication. | Uncharacterized protein YDL176W; Protein of unknown function; predicted by computational methods to be involved in fructose-1,6-bisphosphatase (Fbp1p) degradation; interacts with components of the GID complex; YDL176W is not an essential gene. | 0.600 |
| YHR131C | YJR011C | YHR131C | YJR011C | PH domain-containing protein YHR131C; Putative protein of unknown function; GFP-fusion protein localizes to the cytoplasm; overexpression causes cell cycle delay or arrest; contains a PH domain and binds phosphatidylinositols and other lipids in a large-scale study; YHR131C has a paralog, YNL144C, that arose from the whole genome duplication. | Uncharacterized protein YJR011C; Putative protein of unknown function; GFP-fusion protein expression is induced in response to the DNA-damaging agent MMS. | 0.543 |
| YHR131C | YLR407W | YHR131C | YLR407W | PH domain-containing protein YHR131C; Putative protein of unknown function; GFP-fusion protein localizes to the cytoplasm; overexpression causes cell cycle delay or arrest; contains a PH domain and binds phosphatidylinositols and other lipids in a large-scale study; YHR131C has a paralog, YNL144C, that arose from the whole genome duplication. | Uncharacterized protein YLR407W; Putative protein of unknown function; null mutant displays elongated buds and a large fraction of budded cells have only one nucleus. | 0.656 |
| YJR011C | YDL176W | YJR011C | YDL176W | Uncharacterized protein YJR011C; Putative protein of unknown function; GFP-fusion protein expression is induced in response to the DNA-damaging agent MMS. | Uncharacterized protein YDL176W; Protein of unknown function; predicted by computational methods to be involved in fructose-1,6-bisphosphatase (Fbp1p) degradation; interacts with components of the GID complex; YDL176W is not an essential gene. | 0.660 |
| YJR011C | YHR131C | YJR011C | YHR131C | Uncharacterized protein YJR011C; Putative protein of unknown function; GFP-fusion protein expression is induced in response to the DNA-damaging agent MMS. | PH domain-containing protein YHR131C; Putative protein of unknown function; GFP-fusion protein localizes to the cytoplasm; overexpression causes cell cycle delay or arrest; contains a PH domain and binds phosphatidylinositols and other lipids in a large-scale study; YHR131C has a paralog, YNL144C, that arose from the whole genome duplication. | 0.543 |
| YJR011C | YLR407W | YJR011C | YLR407W | Uncharacterized protein YJR011C; Putative protein of unknown function; GFP-fusion protein expression is induced in response to the DNA-damaging agent MMS. | Uncharacterized protein YLR407W; Putative protein of unknown function; null mutant displays elongated buds and a large fraction of budded cells have only one nucleus. | 0.651 |
| YLR407W | CKA2 | YLR407W | YOR061W | Uncharacterized protein YLR407W; Putative protein of unknown function; null mutant displays elongated buds and a large fraction of budded cells have only one nucleus. | Alpha' catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching. | 0.992 |
| YLR407W | LCB3 | YLR407W | YJL134W | Uncharacterized protein YLR407W; Putative protein of unknown function; null mutant displays elongated buds and a large fraction of budded cells have only one nucleus. | Long-chain base-1-phosphate phosphatase; specific for dihydrosphingosine-1-phosphate, regulates ceramide and long-chain base phosphates levels, involved in incorporation of exogenous long chain bases in sphingolipids; LCB3 has a paralog, YSR3, that arose from the whole genome duplication. | 0.654 |
| YLR407W | PKC1 | YLR407W | YBL105C | Uncharacterized protein YLR407W; Putative protein of unknown function; null mutant displays elongated buds and a large fraction of budded cells have only one nucleus. | Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC). | 0.947 |
