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YLR407W protein (Saccharomyces cerevisiae) - STRING interaction network
"YLR407W" - Putative protein of unknown function in Saccharomyces cerevisiae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
YLR407WPutative protein of unknown function; null mutant displays elongated buds and a large fraction of budded cells have only one nucleus; Deletion results in antifungal drug fluconazole- resistant phenotype (228 aa)    
Predicted Functional Partners:
CKA2
Alpha’ catalytic subunit of casein kinase 2 (CK2), a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerase; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha’ chains contain the catalytic site. May play a role in cell proliferation. Required for cell viability (339 aa)
       
 
  0.856
EGO4
Putative protein of unknown function; expression is regulated by Msn2p/Msn4p (98 aa)
           
  0.749
YIL152W
Putative protein of unknown function (235 aa)
           
  0.743
YOR364W
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YOR365C (122 aa)
           
  0.741
YMR102C
Protein of unknown function; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance; mutant shows increased resistance to azoles; YMR102C is not an essential gene (834 aa)
           
  0.699
YGR283C
Putative S-adenosylmethionine-dependent methyltransferase; may interact with ribosomes, based on co-purification experiments; predicted to be involved in ribosome biogenesis; null mutant is resistant to fluconazole; GFP-fusion protein localizes to t /.../leolus (341 aa)
           
  0.635
AIM32
Protein of unknown function; null mutant is viable and displays elevated frequency of mitochondrial genome loss (311 aa)
           
  0.627
YNL234W
Protein of unknown function with similarity to globins; has a functional heme-binding domain; mutant has aneuploidy tolerance; transcription induced by stress conditions; may be involved in glucose signaling or metabolism; regulated by Rgt1 (426 aa)
           
  0.624
IRC21
Protein of unknown function; may be involved in resistance to carboplatin and cisplatin; null mutant displays increase in spontaneous Rad52p foci; contains a lipid-binding domain and binds cardiolipin in a large-scale study; Involved in resistance to carboplatin and cisplatin. Is probably involved in a pathway contributing to genomic integrity (201 aa)
           
  0.620
LCL1
Putative protein of unknown function; deletion mutant is fluconazole resistant and has long chronological lifespan (101 aa)
           
  0.579
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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