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ECM7 protein (Saccharomyces cerevisiae) - STRING interaction network
"ECM7" - Non-essential putative integral membrane protein with a role in calcium uptake in Saccharomyces cerevisiae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ECM7Non-essential putative integral membrane protein with a role in calcium uptake; mutant has cell wall defects and Ca+ uptake deficiencies; transcription is induced under conditions of zinc deficiency; May be involved in cell wall organization and biogenesis (448 aa)    
Predicted Functional Partners:
CCH1
Voltage-gated high-affinity calcium channel involved in calcium influx in response to some environmental stresses as well as exposure to mating pheromones; interacts and co-localizes with Mid1p, suggesting Cch1p and Mid1p function together; Voltage-gated, high-affinity calcium channel involved in calcium influx in response to some environmental stresses as well as exposure to mating pheromones. Functions together with MID1 to ensure that adequate levels of Ca(2+) are supplied to PMR1 to sustain secretion and growth. Required for growth in low-calcium environments (2039 aa)
           
  0.679
MID1
N-glycosylated integral membrane protein of the ER and plasma membrane; functions as a stretch-activated Ca2+-permeable cation channel required for Ca2+ influx stimulated by pheromone; interacts with Cch1p; forms an oligomer; Calcium-permeable, cation-selective stretch-activated channel (SAC). Required for calcium influx and for vitality of MATa cells in a late, pheromone-induced event of the mating process requiring calcium induced signaling. Functions together with CCH1 to ensure that adequate levels of Ca(2+) are supplied to PMR1 to sustain secretion and growth. Required for growth [...] (548 aa)
           
  0.642
YVC1
Vacuolar cation channel, mediates release of Ca(2+) from the vacuole in response to hyperosmotic shock; Required for release of calcium ions from the vacuole in response to hyperosmotic shock (675 aa)
           
  0.520
YBR226C
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YBR225W (136 aa)
           
  0.519
BSC2
Protein of unknown function, ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression (235 aa)
           
  0.469
YBL081W
Non-essential protein of unknown function; null mutation results in a decrease in plasma membrane electron transport (368 aa)
           
  0.434
ECM19
Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; May be involved in cell wall organization and biogenesis (112 aa)
           
  0.430
YMR262W
Protein of unknown function; interacts weakly with Knr4p; YMR262W is not an essential gene; Putative deoxyribonuclease (313 aa)
           
  0.418
DCV1
Protein of unknown function; deletion mutant shows strong genetic interaction with cdc28-as1 mutant in the presence of 1-NM-PP1 (202 aa)
           
  0.418
FIG1
Integral membrane protein required for efficient mating; may participate in or regulate the low affinity Ca2+ influx system, which affects intracellular signaling and cell-cell fusion during mating; Required for efficient mating (298 aa)
           
  0.418
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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