node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DST1 | FMP27 | YGL043W | YLR454W | General transcription elongation factor TFIIS; enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites; maintains RNAPII elongation activity on ribosomal protein genes during conditions of transcriptional stress; Belongs to the TFS-II family. | Protein FMP27, mitochondrial; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | 0.637 |
DST1 | RPB3 | YGL043W | YIL021W | General transcription elongation factor TFIIS; enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites; maintains RNAPII elongation activity on ribosomal protein genes during conditions of transcriptional stress; Belongs to the TFS-II family. | RNA polymerase II third largest subunit B44; part of central core; similar to prokaryotic alpha subunit. | 0.999 |
DST1 | RPO21 | YGL043W | YDL140C | General transcription elongation factor TFIIS; enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites; maintains RNAPII elongation activity on ribosomal protein genes during conditions of transcriptional stress; Belongs to the TFS-II family. | RNA polymerase II largest subunit B220; part of central core; phosphorylation of C-terminal heptapeptide repeat domain regulates association with transcription and splicing factors; similar to bacterial beta-prime. | 0.999 |
DST1 | SEN1 | YGL043W | YLR430W | General transcription elongation factor TFIIS; enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites; maintains RNAPII elongation activity on ribosomal protein genes during conditions of transcriptional stress; Belongs to the TFS-II family. | Helicase SEN1; ATP-dependent 5' to 3' RNA/DNA and DNA helicase; subunit of the exosome-associated Nrd1p complex that mediates 3' end formation of snRNAs, snoRNAs, CUTs and some mRNAs; helicase-independent role in transcription-coupled repair; coordinates replication with transcription, associating with moving forks and preventing errors that occur when forks encounter transcribed regions; homolog of Senataxin, implicated in Ataxia-Oculomotor Apraxia 2 and a dominant form of juvenile ALS. | 0.539 |
DST1 | SPT6 | YGL043W | YGR116W | General transcription elongation factor TFIIS; enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites; maintains RNAPII elongation activity on ribosomal protein genes during conditions of transcriptional stress; Belongs to the TFS-II family. | Transcription elongation factor SPT6; Nucleosome remodeling protein; functions in various aspects of transcription, chromatin maintenance, and RNA processing; required for the maintenance of chromatin structure during transcription in order to inhibit transcription from promoters within the coding region; required for H3K36 trimethylation but not dimethylation by Set2p. | 0.967 |
FMP27 | DST1 | YLR454W | YGL043W | Protein FMP27, mitochondrial; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | General transcription elongation factor TFIIS; enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites; maintains RNAPII elongation activity on ribosomal protein genes during conditions of transcriptional stress; Belongs to the TFS-II family. | 0.637 |
FMP27 | FSF1 | YLR454W | YOR271C | Protein FMP27, mitochondrial; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | Sideroflexin FSF1; Putative protein; predicted to be an alpha-isopropylmalate carrier; belongs to the sideroblastic-associated protein family; non-tagged protein is detected in purified mitochondria; likely to play a role in iron homeostasis. | 0.606 |
FMP27 | IFM1 | YLR454W | YOL023W | Protein FMP27, mitochondrial; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | Mitochondrial translation initiation factor 2. | 0.632 |
FMP27 | RPB3 | YLR454W | YIL021W | Protein FMP27, mitochondrial; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | RNA polymerase II third largest subunit B44; part of central core; similar to prokaryotic alpha subunit. | 0.797 |
FMP27 | RPO21 | YLR454W | YDL140C | Protein FMP27, mitochondrial; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | RNA polymerase II largest subunit B220; part of central core; phosphorylation of C-terminal heptapeptide repeat domain regulates association with transcription and splicing factors; similar to bacterial beta-prime. | 0.569 |
FMP27 | SEN1 | YLR454W | YLR430W | Protein FMP27, mitochondrial; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | Helicase SEN1; ATP-dependent 5' to 3' RNA/DNA and DNA helicase; subunit of the exosome-associated Nrd1p complex that mediates 3' end formation of snRNAs, snoRNAs, CUTs and some mRNAs; helicase-independent role in transcription-coupled repair; coordinates replication with transcription, associating with moving forks and preventing errors that occur when forks encounter transcribed regions; homolog of Senataxin, implicated in Ataxia-Oculomotor Apraxia 2 and a dominant form of juvenile ALS. | 0.578 |
FMP27 | SPT6 | YLR454W | YGR116W | Protein FMP27, mitochondrial; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | Transcription elongation factor SPT6; Nucleosome remodeling protein; functions in various aspects of transcription, chromatin maintenance, and RNA processing; required for the maintenance of chromatin structure during transcription in order to inhibit transcription from promoters within the coding region; required for H3K36 trimethylation but not dimethylation by Set2p. | 0.550 |
FMP27 | TOM1 | YLR454W | YDR457W | Protein FMP27, mitochondrial; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | E3 ubiquitin ligase of the hect-domain class; has a role in mRNA export from the nucleus and may regulate transcriptional coactivators; involved in degradation of excess histones; interacts with Dia2p and is required for Dia2p degradation; required to target Cdc6p for ubiquitin-mediated destruction during G1 phase; Belongs to the UPL family. TOM1/PTR1 subfamily. | 0.588 |
FMP27 | VPS13 | YLR454W | YLL040C | Protein FMP27, mitochondrial; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | Vacuolar protein sorting-associated protein 13; Protein involved in prospore membrane morphogenesis; peripheral membrane protein that localizes to the prospore membrane and at numerous membrane contact sites; involved in sporulation, vacuolar protein sorting, prospore membrane formation during sporulation, and protein-Golgi retention; required for mitochondrial integrity; contains a PH-like domain; homologous to human CHAC and COH1 which are involved in Chorea-acanthocytosis and Cohen syndrome, respectively. | 0.557 |
FMP27 | YEL025C | YLR454W | YEL025C | Protein FMP27, mitochondrial; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | Uncharacterized protein YEL025C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus. | 0.712 |
FSF1 | FMP27 | YOR271C | YLR454W | Sideroflexin FSF1; Putative protein; predicted to be an alpha-isopropylmalate carrier; belongs to the sideroblastic-associated protein family; non-tagged protein is detected in purified mitochondria; likely to play a role in iron homeostasis. | Protein FMP27, mitochondrial; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | 0.606 |
IFM1 | FMP27 | YOL023W | YLR454W | Mitochondrial translation initiation factor 2. | Protein FMP27, mitochondrial; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | 0.632 |
IFM1 | RPB3 | YOL023W | YIL021W | Mitochondrial translation initiation factor 2. | RNA polymerase II third largest subunit B44; part of central core; similar to prokaryotic alpha subunit. | 0.643 |
RPB3 | DST1 | YIL021W | YGL043W | RNA polymerase II third largest subunit B44; part of central core; similar to prokaryotic alpha subunit. | General transcription elongation factor TFIIS; enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites; maintains RNAPII elongation activity on ribosomal protein genes during conditions of transcriptional stress; Belongs to the TFS-II family. | 0.999 |
RPB3 | FMP27 | YIL021W | YLR454W | RNA polymerase II third largest subunit B44; part of central core; similar to prokaryotic alpha subunit. | Protein FMP27, mitochondrial; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | 0.797 |