STRINGSTRING
YRF1-4 protein (Saccharomyces cerevisiae) - STRING interaction network
"YRF1-4" - Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1 in Saccharomyces cerevisiae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YRF1-4Helicase encoded by the Y’ element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p; Catalyzes DNA unwinding and is involved in telomerase- independent telomere maintenance (1382 aa)    
Predicted Functional Partners:
YRF1-5
Helicase encoded by the Y’ element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p; Catalyzes DNA unwinding and is involved in telomerase- independent telomere maintenance (1796 aa)
     
   
0.990
YLR462W
Putative protein of unknown function with similarity to helicases; YLR462W is within the telomere on the right arm of chromosome XII (202 aa)
     
   
  0.980
YRF1-6
Helicase encoded by the Y’ element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p (1859 aa)
     
   
0.980
YLL067C
Putative Y’ element ATP-dependent helicase (1205 aa)
     
     
0.980
YHR218W
Helicase-like protein encoded within the telomeric Y’ element (603 aa)
     
     
0.980
YHL050C
Putative protein of unknown function, potential Cdc28p substrate (697 aa)
     
     
0.964
YLR464W
Putative protein of unknown function (216 aa)
     
        0.953
YJL225C
Putative Y’ element ATP-dependent helicase; Catalyzes DNA unwinding and is involved in telomerase- independent telomere maintenance (1758 aa)
     
   
0.934
YML133C
Putative Y’ element ATP-dependent helicase; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YML133C contains an intron; Catalyzes DNA unwinding and is involved in telomerase- independent telomere maintenance (1374 aa)
     
     
0.933
YIL177C
Putative Y’ element ATP-dependent helicase; Catalyzes DNA unwinding and is involved in telomerase- independent telomere maintenance (1758 aa)
     
     
0.933
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
Server load: low (8%) [HD]