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RCF1 protein (Saccharomyces cerevisiae) - STRING interaction network
"RCF1" - Putative protein of unknown function in Saccharomyces cerevisiae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
RCF1Putative protein of unknown function; GFP-fusion protein localizes to mitochondria; may interact with respiratory chain complexes III or IV; null mutant is viable and displays reduced frequency of mitochondrial genome loss; Cytochrome c oxidase subunit required for growth under hypoxic conditions. Involved in the assembly of the Complex III- Complex IV supercomplex, as well as in the recruitment of COX13 and RCF2 into cytochrome c oxidase. May also be required for late- stage assembly of the COX12 and COX13 subunits and for cytochrome c oxidase activity (159 aa)    
Predicted Functional Partners:
RCF2
Putative protein of unknown function; non-tagged protein is detected in purified mitochondria; may interact with respiratory chain complex IV; null mutant is viable and displays reduced frequency of mitochondrial genome loss; Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes. May be required for late- stage assembly of the COX12 and COX13 subunits and for cytochrome c oxidase activity (224 aa)
       
  0.991
COX13
Subunit VIa of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; not essential for cytochrome c oxidase activity but may modulate activity in response to ATP; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Not necessary for assembly of the enzyme complex but interacts with ATP and thereby modulates the enzyme activity (129 aa)
     
 
  0.951
COX26
Putative protein of unknown function; may interact with respiratory chain complexes III (ubiquinol-cytochrome c reductase) or IV (cytochrome c oxidase) (66 aa)
     
 
    0.905
COX4
Subunit IV of cytochrome c oxidase, the terminal member of the mitochondrial inner membrane electron transport chain; precursor N-terminal 25 residues are cleaved during mitochondrial import; phosphorylated; spermidine enhances translation; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water (155 aa)
     
      0.878
COR1
Core subunit of the ubiquinol-cytochrome c reductase complex (bc1 complex), which is a component of the mitochondrial inner membrane electron transport chain; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain that generates an electrochemical potential coupled to ATP synthesis. The complex couples electron transfer from ubiquinol to cytochrome c. COR1 may mediate formation of the complex between cytochromes c and c1 (457 aa)
       
      0.868
AIM36
Protein of unknown function; null mutant displays reduced respiratory growth and elevated frequency of mitochondrial genome loss; the authentic, non-tagged protein is detected in purified mitochondria in high-throughput studies (255 aa)
     
 
  0.646
YER189W
Putative protein of unknown function (122 aa)
           
  0.580
YIL152W
Putative protein of unknown function (235 aa)
           
  0.579
YBL112C
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data (105 aa)
           
  0.578
YBL112C
Putative protein of unknown function; YBL112C is contained within TEL02L (105 aa)
           
  0.578
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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