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PRM6 protein (Saccharomyces cerevisiae) - STRING interaction network
"PRM6" - Pheromone-regulated protein, predicted to have 2 transmembrane segments in Saccharomyces cerevisiae
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
PRM6Pheromone-regulated protein, predicted to have 2 transmembrane segments; regulated by Ste12p during mating (352 aa)    
Predicted Functional Partners:
FIG1
Integral membrane protein required for efficient mating; may participate in or regulate the low affinity Ca2+ influx system, which affects intracellular signaling and cell-cell fusion during mating; Required for efficient mating (298 aa)
     
   
  0.876
TRK2
Component of the Trk1p-Trk2p potassium transport system; This protein is required for low-affinity potassium transport (889 aa)
       
 
  0.715
TRK1
Component of the Trk1p-Trk2p potassium transport system; 180 kDa high affinity potassium transporter; phosphorylated in vivo and interacts physically with the phosphatase Ppz1p, suggesting Trk1p acitivy is regulated by phosphorylation; This protein is required for high-affinity potassium transport (1235 aa)
       
 
  0.714
KCH1
Vacuolar protein of unknown function; potential Cdc28p substrate (497 aa)
       
 
0.685
BAR1
Aspartyl protease secreted into the periplasmic space of mating type a cells, helps cells find mating partners, cleaves and inactivates alpha factor allowing cells to recover from alpha-factor-induced cell cycle arrest; This protein called "barrier activity" is excreted by yeast cells mating type a. It is probably a protease that cleaves alpha-factor and thus acts as an antagonist of this mating pheromone and establishes optimal pheromone concentration for conjugation (587 aa)
       
 
  0.652
PRM7
Pheromone-regulated protein, predicted to have one transmembrane segment; promoter contains Gcn4p binding elements (698 aa)
           
  0.541
YIL089W
Protein of unknown function found in the ER and vacuole lumen; overexpression of YIL089W affects endocytic protein trafficking (205 aa)
           
  0.485
PRM5
Pheromone-regulated protein, predicted to have 1 transmembrane segment; induced during cell integrity signaling (318 aa)
           
  0.483
YOR022C
Protein with similarity to bovine phospholipase A1; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Probable phospholipase that hydrolyzes phosphatidic acid (715 aa)
           
  0.480
PRM1
Pheromone-regulated multispanning membrane protein involved in membrane fusion during mating; predicted to have 5 transmembrane segments and a coiled coil domain; localizes to the shmoo tip; regulated by Ste12p; Involved in cell fusion during mating by stabilizing the plasma membrane fusion event (661 aa)
     
   
  0.476
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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