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TCB3 protein (Saccharomyces cerevisiae) - STRING interaction network
"TCB3" - Lipid-binding protein, localized to the bud via specific mRNA transport in Saccharomyces cerevisiae
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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TCB3Lipid-binding protein, localized to the bud via specific mRNA transport; non-tagged protein detected in a phosphorylated state in mitochondria; GFP-fusion protein localizes to the cell periphery; C-termini of Tcb1p, Tcb2p and Tcb3p interact; May play a role in membrane trafficking (1545 aa)    
Predicted Functional Partners:
FLC1
Putative FAD transporter; required for uptake of FAD into endoplasmic reticulum; involved in cell wall maintenance; May be responsible for the transport of FAD into the endoplasmic reticulum lumen, where it is required for oxidative protein folding (793 aa)
       
      0.843
TCB1
Lipid-binding protein containing three calcium and lipid binding domains; non-tagged protein localizes to mitochondria and GFP-fusion protein localizes to the cell periphery; C-termini of Tcb1p, Tcb2p and Tcb3p interact; May play a role in membrane trafficking (1186 aa)
     
 
0.819
QDR2
Multidrug transporter of the major facilitator superfamily, required for resistance to quinidine, barban, cisplatin, and bleomycin; may have a role in potassium uptake; Multidrug resistance transporter involved in resistance and adaptation to quinidine and to the herbicide barban (4-chloro- 2-butynyl [3-chlorophenyl] carbamate). Implicated in potassium uptake (542 aa)
       
 
  0.812
INA1
Putative protein of unknown function; YLR413W is not an essential gene (675 aa)
       
      0.806
RPL28
Ribosomal 60S subunit protein L28; homologous to mammalian ribosomal protein L27A and bacterial L15; may have peptidyl transferase activity; can mutate to cycloheximide resistance (149 aa)
       
      0.801
TCB2
Bud-specific protein with a potential role in membrane trafficking; GFP-fusion protein migrates from the cell surface to intracellular vesicles near vacuole; contains 3 calcium and lipid binding domains; mRNA is targeted to the bud; May play a role in membrane trafficking (1178 aa)
       
 
0.742
RSP5
E3 ubiquitin ligase of the NEDD4 family; involved in regulating many cellular processes including MVB sorting, heat shock response, transcription, endocytosis, and ribosome stability; human homolog is involved in Liddle syndrome; mutant tolerates an /.../dy; ubiquitylates Sec23p; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Component of a RSP5 ubiquitin ligase complex which specifies polyubiquitination and intracellular trafficking of the general a [...] (809 aa)
     
 
  0.729
SCS22
Protein involved in regulation of phospholipid metabolism; homolog of Scs2p; similar to D. melanogaster inturned protein; Targets proteins containing a FFAT motif to membranes (By similarity). Involved in regulation of phospholipid metabolism (175 aa)
           
  0.726
KTR3
Putative alpha-1,2-mannosyltransferase involved in O- and N-linked protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family; Svp26p mediates uptake of Ktr3p into COPII vesicles; Possible glycosyltransferase (404 aa)
       
      0.718
GSC2
Catalytic subunit of 1,3-beta-glucan synthase, involved in formation of the inner layer of the spore wall; activity positively regulated by Rho1p and negatively by Smk1p; has similarity to an alternate catalytic subunit, Fks1p (Gsc1p); Alternate catalytic subunit of the 1,3-beta-glucan synthase (GS). Synthesizes 1,3-beta-glucan, a major structural component of the yeast cell wall. Required for spore wall assembly. Negative regulation of activity by SMK1 is important for spore wall deposition. Activity is positively regulated by RHO1 (1895 aa)
       
 
  0.706
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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