node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APC2 | YMR027W | YLR127C | YMR027W | Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C); which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; component of the catalytic core of the APC/C; has similarity to cullin Cdc53p. | Damage-control phosphatase YMR027W; A metal-dependent phosphatase, part of the DUF89 protein family; dephosphorylates fructose-1-phosphate; human ortholog, C6orf211 is involved in response to DNA damage; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; YMR027W is not an essential gene; Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily. | 0.537 |
APT1 | APT2 | YML022W | YDR441C | Adenine phosphoribosyltransferase; catalyzes the formation of AMP from adenine and 5-phosphoribosylpyrophosphate; involved in the salvage pathway of purine nucleotide biosynthesis; APT1 has a paralog, APT2, that arose from the whole genome duplication. | Potential adenine phosphoribosyltransferase; encodes a protein with similarity to adenine phosphoribosyltransferase, but artificially expressed protein exhibits no enzymatic activity; APT2 has a paralog, APT1, that arose from the whole genome duplication. | 0.990 |
APT1 | FCY22 | YML022W | YER060W-A | Adenine phosphoribosyltransferase; catalyzes the formation of AMP from adenine and 5-phosphoribosylpyrophosphate; involved in the salvage pathway of purine nucleotide biosynthesis; APT1 has a paralog, APT2, that arose from the whole genome duplication. | Putative purine-cytosine permease; very similar to Fcy2p but cannot substitute for its function; Belongs to the purine-cytosine permease (2.A.39) family. | 0.441 |
APT1 | XPT1 | YML022W | YJR133W | Adenine phosphoribosyltransferase; catalyzes the formation of AMP from adenine and 5-phosphoribosylpyrophosphate; involved in the salvage pathway of purine nucleotide biosynthesis; APT1 has a paralog, APT2, that arose from the whole genome duplication. | Xanthine phosphoribosyltransferase 1; Xanthine-guanine phosphoribosyl transferase; required for xanthine utilization and for optimal utilization of guanine. | 0.625 |
APT1 | YMR027W | YML022W | YMR027W | Adenine phosphoribosyltransferase; catalyzes the formation of AMP from adenine and 5-phosphoribosylpyrophosphate; involved in the salvage pathway of purine nucleotide biosynthesis; APT1 has a paralog, APT2, that arose from the whole genome duplication. | Damage-control phosphatase YMR027W; A metal-dependent phosphatase, part of the DUF89 protein family; dephosphorylates fructose-1-phosphate; human ortholog, C6orf211 is involved in response to DNA damage; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; YMR027W is not an essential gene; Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily. | 0.597 |
APT2 | APT1 | YDR441C | YML022W | Potential adenine phosphoribosyltransferase; encodes a protein with similarity to adenine phosphoribosyltransferase, but artificially expressed protein exhibits no enzymatic activity; APT2 has a paralog, APT1, that arose from the whole genome duplication. | Adenine phosphoribosyltransferase; catalyzes the formation of AMP from adenine and 5-phosphoribosylpyrophosphate; involved in the salvage pathway of purine nucleotide biosynthesis; APT1 has a paralog, APT2, that arose from the whole genome duplication. | 0.990 |
APT2 | FCY21 | YDR441C | YER060W | Potential adenine phosphoribosyltransferase; encodes a protein with similarity to adenine phosphoribosyltransferase, but artificially expressed protein exhibits no enzymatic activity; APT2 has a paralog, APT1, that arose from the whole genome duplication. | Putative purine-cytosine permease; very similar to Fcy2p but cannot substitute for its function; Belongs to the purine-cytosine permease (2.A.39) family. | 0.405 |
APT2 | FCY22 | YDR441C | YER060W-A | Potential adenine phosphoribosyltransferase; encodes a protein with similarity to adenine phosphoribosyltransferase, but artificially expressed protein exhibits no enzymatic activity; APT2 has a paralog, APT1, that arose from the whole genome duplication. | Putative purine-cytosine permease; very similar to Fcy2p but cannot substitute for its function; Belongs to the purine-cytosine permease (2.A.39) family. | 0.448 |
APT2 | XPT1 | YDR441C | YJR133W | Potential adenine phosphoribosyltransferase; encodes a protein with similarity to adenine phosphoribosyltransferase, but artificially expressed protein exhibits no enzymatic activity; APT2 has a paralog, APT1, that arose from the whole genome duplication. | Xanthine phosphoribosyltransferase 1; Xanthine-guanine phosphoribosyl transferase; required for xanthine utilization and for optimal utilization of guanine. | 0.747 |
APT2 | YMR027W | YDR441C | YMR027W | Potential adenine phosphoribosyltransferase; encodes a protein with similarity to adenine phosphoribosyltransferase, but artificially expressed protein exhibits no enzymatic activity; APT2 has a paralog, APT1, that arose from the whole genome duplication. | Damage-control phosphatase YMR027W; A metal-dependent phosphatase, part of the DUF89 protein family; dephosphorylates fructose-1-phosphate; human ortholog, C6orf211 is involved in response to DNA damage; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; YMR027W is not an essential gene; Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily. | 0.601 |
FCY21 | APT2 | YER060W | YDR441C | Putative purine-cytosine permease; very similar to Fcy2p but cannot substitute for its function; Belongs to the purine-cytosine permease (2.A.39) family. | Potential adenine phosphoribosyltransferase; encodes a protein with similarity to adenine phosphoribosyltransferase, but artificially expressed protein exhibits no enzymatic activity; APT2 has a paralog, APT1, that arose from the whole genome duplication. | 0.405 |
FCY21 | YMR027W | YER060W | YMR027W | Putative purine-cytosine permease; very similar to Fcy2p but cannot substitute for its function; Belongs to the purine-cytosine permease (2.A.39) family. | Damage-control phosphatase YMR027W; A metal-dependent phosphatase, part of the DUF89 protein family; dephosphorylates fructose-1-phosphate; human ortholog, C6orf211 is involved in response to DNA damage; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; YMR027W is not an essential gene; Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily. | 0.551 |
FCY22 | APT1 | YER060W-A | YML022W | Putative purine-cytosine permease; very similar to Fcy2p but cannot substitute for its function; Belongs to the purine-cytosine permease (2.A.39) family. | Adenine phosphoribosyltransferase; catalyzes the formation of AMP from adenine and 5-phosphoribosylpyrophosphate; involved in the salvage pathway of purine nucleotide biosynthesis; APT1 has a paralog, APT2, that arose from the whole genome duplication. | 0.441 |
FCY22 | APT2 | YER060W-A | YDR441C | Putative purine-cytosine permease; very similar to Fcy2p but cannot substitute for its function; Belongs to the purine-cytosine permease (2.A.39) family. | Potential adenine phosphoribosyltransferase; encodes a protein with similarity to adenine phosphoribosyltransferase, but artificially expressed protein exhibits no enzymatic activity; APT2 has a paralog, APT1, that arose from the whole genome duplication. | 0.448 |
FCY22 | XPT1 | YER060W-A | YJR133W | Putative purine-cytosine permease; very similar to Fcy2p but cannot substitute for its function; Belongs to the purine-cytosine permease (2.A.39) family. | Xanthine phosphoribosyltransferase 1; Xanthine-guanine phosphoribosyl transferase; required for xanthine utilization and for optimal utilization of guanine. | 0.470 |
FCY22 | YMR027W | YER060W-A | YMR027W | Putative purine-cytosine permease; very similar to Fcy2p but cannot substitute for its function; Belongs to the purine-cytosine permease (2.A.39) family. | Damage-control phosphatase YMR027W; A metal-dependent phosphatase, part of the DUF89 protein family; dephosphorylates fructose-1-phosphate; human ortholog, C6orf211 is involved in response to DNA damage; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; YMR027W is not an essential gene; Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily. | 0.630 |
PPT1 | YMR027W | YGR123C | YMR027W | Protein serine/threonine phosphatase; regulates Hsp90 chaperone by affecting its ATPase and cochaperone binding activities; has similarity to human phosphatase PP5; present in both the nucleus and cytoplasm; expressed during logarithmic growth; Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily. | Damage-control phosphatase YMR027W; A metal-dependent phosphatase, part of the DUF89 protein family; dephosphorylates fructose-1-phosphate; human ortholog, C6orf211 is involved in response to DNA damage; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; YMR027W is not an essential gene; Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily. | 0.773 |
SGD1 | YMR027W | YLR336C | YMR027W | Suppressor of glycerol defect protein 1; Essential nuclear protein; required for biogenesis of the small ribosomal subunit; has a possible role in the osmoregulatory glycerol response; putative homolog of human NOM1 which is implicated in acute myeloid leukemia. | Damage-control phosphatase YMR027W; A metal-dependent phosphatase, part of the DUF89 protein family; dephosphorylates fructose-1-phosphate; human ortholog, C6orf211 is involved in response to DNA damage; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; YMR027W is not an essential gene; Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily. | 0.537 |
VMA10 | VMA13 | YHR039C-A | YPR036W | Subunit G of the V1 peripheral membrane domain of V-ATPase; part of the electrogenic proton pump found throughout the endomembrane system; involved in vacuolar acidification; the V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase) has eight subunits. | Subunit H of the V1 peripheral membrane domain of V-ATPase; part of the electrogenic proton pump found throughout the endomembrane system; serves as an activator or a structural stabilizer of the V-ATPase; the V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase) has eight subunits. | 0.999 |
VMA10 | YMR027W | YHR039C-A | YMR027W | Subunit G of the V1 peripheral membrane domain of V-ATPase; part of the electrogenic proton pump found throughout the endomembrane system; involved in vacuolar acidification; the V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase) has eight subunits. | Damage-control phosphatase YMR027W; A metal-dependent phosphatase, part of the DUF89 protein family; dephosphorylates fructose-1-phosphate; human ortholog, C6orf211 is involved in response to DNA damage; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; YMR027W is not an essential gene; Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily. | 0.778 |