| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NNR1 | YBR053C | YNL200C | YBR053C | NADHX epimerase; catalyzes isomerization of (R)- and (S)-NADHX; homologous to AIBP in mammals and the N- terminal domain of YjeF in E.coli; enzyme is widespread in eukaryotes, prokaryotes and archaea; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the NnrE/AIBP family. | Uncharacterized protein YBR053C; Putative protein of unknown function; induced by cell wall perturbation. | 0.755 |
| NNR1 | YDR061W | YNL200C | YDR061W | NADHX epimerase; catalyzes isomerization of (R)- and (S)-NADHX; homologous to AIBP in mammals and the N- terminal domain of YjeF in E.coli; enzyme is widespread in eukaryotes, prokaryotes and archaea; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the NnrE/AIBP family. | Protein with similarity to ABC transporter family members; lacks predicted membrane-spanning regions; transcriptionally activated by Yrm1p along with genes involved in multidrug resistance. | 0.566 |
| NNR1 | YER134C | YNL200C | YER134C | NADHX epimerase; catalyzes isomerization of (R)- and (S)-NADHX; homologous to AIBP in mammals and the N- terminal domain of YjeF in E.coli; enzyme is widespread in eukaryotes, prokaryotes and archaea; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the NnrE/AIBP family. | Magnesium-dependent acid phosphatase; member of the haloacid dehalogenase superfamily; non-essential gene; Belongs to the HAD-like hydrolase superfamily. | 0.484 |
| NNR1 | YMR027W | YNL200C | YMR027W | NADHX epimerase; catalyzes isomerization of (R)- and (S)-NADHX; homologous to AIBP in mammals and the N- terminal domain of YjeF in E.coli; enzyme is widespread in eukaryotes, prokaryotes and archaea; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the NnrE/AIBP family. | Damage-control phosphatase YMR027W; A metal-dependent phosphatase, part of the DUF89 protein family; dephosphorylates fructose-1-phosphate; human ortholog, C6orf211 is involved in response to DNA damage; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; YMR027W is not an essential gene; Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily. | 0.588 |
| NNR1 | YMR090W | YNL200C | YMR090W | NADHX epimerase; catalyzes isomerization of (R)- and (S)-NADHX; homologous to AIBP in mammals and the N- terminal domain of YjeF in E.coli; enzyme is widespread in eukaryotes, prokaryotes and archaea; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the NnrE/AIBP family. | UPF0659 protein YMR090W; Putative protein of unknown function; similar to DTDP-glucose 4,6-dehydratases; GFP-fusion protein localizes to the cytoplasm; up-regulated in response to the fungicide mancozeb; not essential for viability; Belongs to the UPF0659 family. | 0.738 |
| NNR1 | YOR289W | YNL200C | YOR289W | NADHX epimerase; catalyzes isomerization of (R)- and (S)-NADHX; homologous to AIBP in mammals and the N- terminal domain of YjeF in E.coli; enzyme is widespread in eukaryotes, prokaryotes and archaea; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the NnrE/AIBP family. | Uncharacterized protein YOR289W; Putative protein of unknown function; transcription induced by the unfolded protein response; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus. | 0.823 |
| PPT1 | YMR027W | YGR123C | YMR027W | Protein serine/threonine phosphatase; regulates Hsp90 chaperone by affecting its ATPase and cochaperone binding activities; has similarity to human phosphatase PP5; present in both the nucleus and cytoplasm; expressed during logarithmic growth; Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily. | Damage-control phosphatase YMR027W; A metal-dependent phosphatase, part of the DUF89 protein family; dephosphorylates fructose-1-phosphate; human ortholog, C6orf211 is involved in response to DNA damage; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; YMR027W is not an essential gene; Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily. | 0.773 |
| VMA10 | VMA13 | YHR039C-A | YPR036W | Subunit G of the V1 peripheral membrane domain of V-ATPase; part of the electrogenic proton pump found throughout the endomembrane system; involved in vacuolar acidification; the V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase) has eight subunits. | Subunit H of the V1 peripheral membrane domain of V-ATPase; part of the electrogenic proton pump found throughout the endomembrane system; serves as an activator or a structural stabilizer of the V-ATPase; the V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase) has eight subunits. | 0.999 |
| VMA10 | YMR027W | YHR039C-A | YMR027W | Subunit G of the V1 peripheral membrane domain of V-ATPase; part of the electrogenic proton pump found throughout the endomembrane system; involved in vacuolar acidification; the V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase) has eight subunits. | Damage-control phosphatase YMR027W; A metal-dependent phosphatase, part of the DUF89 protein family; dephosphorylates fructose-1-phosphate; human ortholog, C6orf211 is involved in response to DNA damage; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; YMR027W is not an essential gene; Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily. | 0.958 |
| VMA13 | VMA10 | YPR036W | YHR039C-A | Subunit H of the V1 peripheral membrane domain of V-ATPase; part of the electrogenic proton pump found throughout the endomembrane system; serves as an activator or a structural stabilizer of the V-ATPase; the V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase) has eight subunits. | Subunit G of the V1 peripheral membrane domain of V-ATPase; part of the electrogenic proton pump found throughout the endomembrane system; involved in vacuolar acidification; the V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase) has eight subunits. | 0.999 |
| VMA13 | YMR027W | YPR036W | YMR027W | Subunit H of the V1 peripheral membrane domain of V-ATPase; part of the electrogenic proton pump found throughout the endomembrane system; serves as an activator or a structural stabilizer of the V-ATPase; the V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase) has eight subunits. | Damage-control phosphatase YMR027W; A metal-dependent phosphatase, part of the DUF89 protein family; dephosphorylates fructose-1-phosphate; human ortholog, C6orf211 is involved in response to DNA damage; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; YMR027W is not an essential gene; Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily. | 0.955 |
| XPT1 | YMR027W | YJR133W | YMR027W | Xanthine phosphoribosyltransferase 1; Xanthine-guanine phosphoribosyl transferase; required for xanthine utilization and for optimal utilization of guanine. | Damage-control phosphatase YMR027W; A metal-dependent phosphatase, part of the DUF89 protein family; dephosphorylates fructose-1-phosphate; human ortholog, C6orf211 is involved in response to DNA damage; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; YMR027W is not an essential gene; Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily. | 0.548 |
| YBR053C | NNR1 | YBR053C | YNL200C | Uncharacterized protein YBR053C; Putative protein of unknown function; induced by cell wall perturbation. | NADHX epimerase; catalyzes isomerization of (R)- and (S)-NADHX; homologous to AIBP in mammals and the N- terminal domain of YjeF in E.coli; enzyme is widespread in eukaryotes, prokaryotes and archaea; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the NnrE/AIBP family. | 0.755 |
| YBR053C | YDR061W | YBR053C | YDR061W | Uncharacterized protein YBR053C; Putative protein of unknown function; induced by cell wall perturbation. | Protein with similarity to ABC transporter family members; lacks predicted membrane-spanning regions; transcriptionally activated by Yrm1p along with genes involved in multidrug resistance. | 0.755 |
| YBR053C | YER134C | YBR053C | YER134C | Uncharacterized protein YBR053C; Putative protein of unknown function; induced by cell wall perturbation. | Magnesium-dependent acid phosphatase; member of the haloacid dehalogenase superfamily; non-essential gene; Belongs to the HAD-like hydrolase superfamily. | 0.675 |
| YBR053C | YMR027W | YBR053C | YMR027W | Uncharacterized protein YBR053C; Putative protein of unknown function; induced by cell wall perturbation. | Damage-control phosphatase YMR027W; A metal-dependent phosphatase, part of the DUF89 protein family; dephosphorylates fructose-1-phosphate; human ortholog, C6orf211 is involved in response to DNA damage; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; YMR027W is not an essential gene; Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily. | 0.765 |
| YBR053C | YMR090W | YBR053C | YMR090W | Uncharacterized protein YBR053C; Putative protein of unknown function; induced by cell wall perturbation. | UPF0659 protein YMR090W; Putative protein of unknown function; similar to DTDP-glucose 4,6-dehydratases; GFP-fusion protein localizes to the cytoplasm; up-regulated in response to the fungicide mancozeb; not essential for viability; Belongs to the UPF0659 family. | 0.742 |
| YBR053C | YOR289W | YBR053C | YOR289W | Uncharacterized protein YBR053C; Putative protein of unknown function; induced by cell wall perturbation. | Uncharacterized protein YOR289W; Putative protein of unknown function; transcription induced by the unfolded protein response; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus. | 0.799 |
| YDR061W | NNR1 | YDR061W | YNL200C | Protein with similarity to ABC transporter family members; lacks predicted membrane-spanning regions; transcriptionally activated by Yrm1p along with genes involved in multidrug resistance. | NADHX epimerase; catalyzes isomerization of (R)- and (S)-NADHX; homologous to AIBP in mammals and the N- terminal domain of YjeF in E.coli; enzyme is widespread in eukaryotes, prokaryotes and archaea; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the NnrE/AIBP family. | 0.566 |
| YDR061W | YBR053C | YDR061W | YBR053C | Protein with similarity to ABC transporter family members; lacks predicted membrane-spanning regions; transcriptionally activated by Yrm1p along with genes involved in multidrug resistance. | Uncharacterized protein YBR053C; Putative protein of unknown function; induced by cell wall perturbation. | 0.755 |
