node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARO1 | ARO2 | YDR127W | YGL148W | 3-phosphoshikimate 1-carboxyvinyltransferase; Pentafunctional arom protein; catalyzes steps 2 through 6 in the biosynthesis of chorismate, which is a precursor to aromatic amino acids; In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. In the 3rd section; belongs to the shikimate kinase family. In the C-terminal section; belongs to the shikimate dehydrogenase family. | Bifunctional chorismate synthase and flavin reductase; catalyzes the conversion of 5-enolpyruvylshikimate 3-phosphate (EPSP) to form chorismate, which is a precursor to aromatic amino acids; protein abundance increases in response to DNA replication stress. | 0.999 |
ARO1 | DLT1 | YDR127W | YMR126C | 3-phosphoshikimate 1-carboxyvinyltransferase; Pentafunctional arom protein; catalyzes steps 2 through 6 in the biosynthesis of chorismate, which is a precursor to aromatic amino acids; In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. In the 3rd section; belongs to the shikimate kinase family. In the C-terminal section; belongs to the shikimate dehydrogenase family. | Defect at low temperature protein 1; Protein of unknown function; mutant sensitive to 6-azauracil (6AU) and mycophenolic acid (MPA); Belongs to the DLT1 family. | 0.531 |
ARO1 | MTC2 | YDR127W | YKL098W | 3-phosphoshikimate 1-carboxyvinyltransferase; Pentafunctional arom protein; catalyzes steps 2 through 6 in the biosynthesis of chorismate, which is a precursor to aromatic amino acids; In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. In the 3rd section; belongs to the shikimate kinase family. In the C-terminal section; belongs to the shikimate dehydrogenase family. | Protein of unknown function; mtc2 is synthetically sick with cdc13-1; Belongs to the MTC2 family. | 0.518 |
ARO1 | MTC4 | YDR127W | YBR255W | 3-phosphoshikimate 1-carboxyvinyltransferase; Pentafunctional arom protein; catalyzes steps 2 through 6 in the biosynthesis of chorismate, which is a precursor to aromatic amino acids; In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. In the 3rd section; belongs to the shikimate kinase family. In the C-terminal section; belongs to the shikimate dehydrogenase family. | Maintenance of telomere capping protein 4; Protein of unknown function; required for normal growth rate at 15 degrees C; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; mtc4 is synthetically sick with cdc13-1. | 0.560 |
ARO2 | ARO1 | YGL148W | YDR127W | Bifunctional chorismate synthase and flavin reductase; catalyzes the conversion of 5-enolpyruvylshikimate 3-phosphate (EPSP) to form chorismate, which is a precursor to aromatic amino acids; protein abundance increases in response to DNA replication stress. | 3-phosphoshikimate 1-carboxyvinyltransferase; Pentafunctional arom protein; catalyzes steps 2 through 6 in the biosynthesis of chorismate, which is a precursor to aromatic amino acids; In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. In the 3rd section; belongs to the shikimate kinase family. In the C-terminal section; belongs to the shikimate dehydrogenase family. | 0.999 |
ARO2 | CSF1 | YGL148W | YLR087C | Bifunctional chorismate synthase and flavin reductase; catalyzes the conversion of 5-enolpyruvylshikimate 3-phosphate (EPSP) to form chorismate, which is a precursor to aromatic amino acids; protein abundance increases in response to DNA replication stress. | Protein required for fermentation at low temperature; plays a role in the maturation of secretory proteins; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the CSF1 family. | 0.456 |
ARO2 | DLT1 | YGL148W | YMR126C | Bifunctional chorismate synthase and flavin reductase; catalyzes the conversion of 5-enolpyruvylshikimate 3-phosphate (EPSP) to form chorismate, which is a precursor to aromatic amino acids; protein abundance increases in response to DNA replication stress. | Defect at low temperature protein 1; Protein of unknown function; mutant sensitive to 6-azauracil (6AU) and mycophenolic acid (MPA); Belongs to the DLT1 family. | 0.620 |
ARO2 | MTC2 | YGL148W | YKL098W | Bifunctional chorismate synthase and flavin reductase; catalyzes the conversion of 5-enolpyruvylshikimate 3-phosphate (EPSP) to form chorismate, which is a precursor to aromatic amino acids; protein abundance increases in response to DNA replication stress. | Protein of unknown function; mtc2 is synthetically sick with cdc13-1; Belongs to the MTC2 family. | 0.540 |
ARO2 | MTC4 | YGL148W | YBR255W | Bifunctional chorismate synthase and flavin reductase; catalyzes the conversion of 5-enolpyruvylshikimate 3-phosphate (EPSP) to form chorismate, which is a precursor to aromatic amino acids; protein abundance increases in response to DNA replication stress. | Maintenance of telomere capping protein 4; Protein of unknown function; required for normal growth rate at 15 degrees C; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; mtc4 is synthetically sick with cdc13-1. | 0.696 |
ARO2 | MTC6 | YGL148W | YHR151C | Bifunctional chorismate synthase and flavin reductase; catalyzes the conversion of 5-enolpyruvylshikimate 3-phosphate (EPSP) to form chorismate, which is a precursor to aromatic amino acids; protein abundance increases in response to DNA replication stress. | Protein of unknown function; mtc6 is synthetically sick with cdc13-1; SWAT-GFP and mCherry fusion proteins localize to the vacuole while SWAT-GFP fusion also localizes to the endoplasmic reticulum. | 0.455 |
CSF1 | ARO2 | YLR087C | YGL148W | Protein required for fermentation at low temperature; plays a role in the maturation of secretory proteins; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the CSF1 family. | Bifunctional chorismate synthase and flavin reductase; catalyzes the conversion of 5-enolpyruvylshikimate 3-phosphate (EPSP) to form chorismate, which is a precursor to aromatic amino acids; protein abundance increases in response to DNA replication stress. | 0.456 |
CSF1 | DLT1 | YLR087C | YMR126C | Protein required for fermentation at low temperature; plays a role in the maturation of secretory proteins; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the CSF1 family. | Defect at low temperature protein 1; Protein of unknown function; mutant sensitive to 6-azauracil (6AU) and mycophenolic acid (MPA); Belongs to the DLT1 family. | 0.792 |
CSF1 | MAY24 | YLR087C | YPR153W | Protein required for fermentation at low temperature; plays a role in the maturation of secretory proteins; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the CSF1 family. | Uncharacterized protein YPR153W; Protein of unknown function. | 0.435 |
CSF1 | MTC2 | YLR087C | YKL098W | Protein required for fermentation at low temperature; plays a role in the maturation of secretory proteins; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the CSF1 family. | Protein of unknown function; mtc2 is synthetically sick with cdc13-1; Belongs to the MTC2 family. | 0.759 |
CSF1 | MTC4 | YLR087C | YBR255W | Protein required for fermentation at low temperature; plays a role in the maturation of secretory proteins; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the CSF1 family. | Maintenance of telomere capping protein 4; Protein of unknown function; required for normal growth rate at 15 degrees C; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; mtc4 is synthetically sick with cdc13-1. | 0.728 |
CSF1 | MTC6 | YLR087C | YHR151C | Protein required for fermentation at low temperature; plays a role in the maturation of secretory proteins; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the CSF1 family. | Protein of unknown function; mtc6 is synthetically sick with cdc13-1; SWAT-GFP and mCherry fusion proteins localize to the vacuole while SWAT-GFP fusion also localizes to the endoplasmic reticulum. | 0.725 |
CSF1 | YDL172C | YLR087C | YDL172C | Protein required for fermentation at low temperature; plays a role in the maturation of secretory proteins; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the CSF1 family. | Putative uncharacterized protein YDL172C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | 0.552 |
DLT1 | ARO1 | YMR126C | YDR127W | Defect at low temperature protein 1; Protein of unknown function; mutant sensitive to 6-azauracil (6AU) and mycophenolic acid (MPA); Belongs to the DLT1 family. | 3-phosphoshikimate 1-carboxyvinyltransferase; Pentafunctional arom protein; catalyzes steps 2 through 6 in the biosynthesis of chorismate, which is a precursor to aromatic amino acids; In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. In the 3rd section; belongs to the shikimate kinase family. In the C-terminal section; belongs to the shikimate dehydrogenase family. | 0.531 |
DLT1 | ARO2 | YMR126C | YGL148W | Defect at low temperature protein 1; Protein of unknown function; mutant sensitive to 6-azauracil (6AU) and mycophenolic acid (MPA); Belongs to the DLT1 family. | Bifunctional chorismate synthase and flavin reductase; catalyzes the conversion of 5-enolpyruvylshikimate 3-phosphate (EPSP) to form chorismate, which is a precursor to aromatic amino acids; protein abundance increases in response to DNA replication stress. | 0.620 |
DLT1 | CSF1 | YMR126C | YLR087C | Defect at low temperature protein 1; Protein of unknown function; mutant sensitive to 6-azauracil (6AU) and mycophenolic acid (MPA); Belongs to the DLT1 family. | Protein required for fermentation at low temperature; plays a role in the maturation of secretory proteins; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the CSF1 family. | 0.792 |