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MSS11 protein (Saccharomyces cerevisiae) - STRING interaction network
"MSS11" - Transcription factor involved in regulation of invasive growth and starch degradation in Saccharomyces cerevisiae
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MSS11Transcription factor involved in regulation of invasive growth and starch degradation; controls the activation of MUC1 and STA2 in response to nutritional signals; Transcription factor that regulates pseudohyphal differentiation, invasive growth, floculation, adhesion and starch metabolism in response to nutrient availability (758 aa)    
Predicted Functional Partners:
STE12
Transcription factor that is activated by a MAPK signaling cascade; activates genes involved in mating or pseudohyphal/invasive growth pathways; cooperates with Tec1p transcription factor to regulate genes specific for invasive growth; Binds to the DNA sequence mediating pheromone induction (called the pheromone response element = PRE) which is found in the upstream control region of several a-, alpha- and haploid- specific genes. Involved in mating of haploids and in pseudohyphae formation in diploids (688 aa)
       
  0.981
FLO8
Transcription factor required for flocculation, diploid filamentous growth, and haploid invasive growth; genome reference strain S288C and most laboratory strains have a mutation in this gene; Required for diploid filamentous growth, haploid invasive growth and flocculation. Putative transcriptional activator of FLO1 (799 aa)
       
 
  0.936
FLO11
GPI-anchored cell surface glycoprotein (flocculin); required for pseudohyphal formation, invasive growth, flocculation, and biofilms; transcriptionally regulated by the MAPK pathway (via Ste12p and Tec1p) and the cAMP pathway (via Flo8p); required f /.../ formation of fibrous interconnections between cells in a colony of a wild S. cerevisiae strain; Cell wall protein that participates in adhesive cell- cell interactions during yeast flocculation, a reversible, asexual and Ca(2+)-dependent process in which cells adhere to form aggregates (flocs) consisting of thousands of cells. Also in [...] (1367 aa)
       
 
  0.935
MSN1
Transcriptional activator involved in regulation of invertase and glucoamylase expression, invasive growth and pseudohyphal differentiation, iron uptake, chromium accumulation, and response to osmotic stress; localizes to the nucleus; May function as a transcriptional activator. Increased dosage of MSN1 restores invertase expression in yeast mutants defective in the SNF1 protein kinase, and msn1 disruption reduced derepression of invertase in the wild-type. May affect SUC2 expression. Expression of MSN1 enhances growth in iron-limiting conditions (382 aa)
       
 
  0.897
TEC1
Transcription factor targeting filamentation genes and Ty1 expression; Ste12p activation of most filamentation gene promoters depends on Tec1p and Tec1p transcriptional activity is dependent on its association with Ste12p; binds to TCS elements upst /.../f filamentation genes, which are regulated by Tec1p/Ste12p/Dig1p complex; competes with Dig2p for binding to Ste12p/Dig1p; positive regulator of chronological life span; TEA/ATTS DNA-binding domain family member; TEC1 is involved in the activation of TY1 and TY1- mediated gene expression. It is not involved in mating or sporulation processes (486 aa)
       
 
  0.896
MEP2
Ammonium permease involved in regulation of pseudohyphal growth; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulation; Transporter for ammonium (both charged and uncharged NH3 and NH4) to use as a nitrogen source. The affinity of MEP2 is about twenty times higher than that of MEP1. MEP3 has the lowest affinity. Under ammonium limitation acts as an ammonium sensor, generating a signal that leads to pseudohyphal growth (499 aa)
       
 
  0.841
MFG1
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YDL233W is not an essential gene; Transcriptional regulator with a general role in all morphogenetically distinct forms of filamentous growth, namely haploid invasive growth, biofilm formation, and diploid pseudohyphal growth. May control FLO11 gene expression as part of a promoter-bound complex with FLO8 and MSS1 (458 aa)
       
 
  0.815
FLO10
Lectin-like protein with similarity to Flo1p, thought to be involved in flocculation; Cell wall protein that participates directly in adhesive cell-cell interactions during yeast flocculation, a reversible, asexual and Ca(2+)-dependent process in which cells adhere to form aggregates (flocs) consisting of thousands of cells. The lectin- like protein sticks out of the cell wall of flocculent cells and selectively binds mannose residues in the cell walls of adjacent cells. Activity is inhibited by mannose, glucose, maltose and sucrose. Also involved in cell-substrate adhesion, haploid in [...] (1169 aa)
       
 
  0.805
MDH2
Cytoplasmic malate dehydrogenase, one of three isozymes that catalyze interconversion of malate and oxaloacetate; involved in the glyoxylate cycle and gluconeogenesis during growth on two-carbon compounds; interacts with Pck1p and Fbp1; The isoenzyme MDH2 may function primarily in the glyoxylate cycle (377 aa)
       
      0.800
SFL1
Transcriptional repressor and activator; involved in repression of flocculation-related genes, and activation of stress responsive genes; negatively regulated by cAMP-dependent protein kinase A subunit Tpk2p; Involved in cell surface assembly and regulation of the gene related to flocculation (asexual cell aggregation). Mutations in SFL1 causes constitutive cell aggregation (766 aa)
       
 
  0.762
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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