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CTL1 protein (Saccharomyces cerevisiae) - STRING interaction network
"CTL1" - RNA 5'-triphosphatase, localizes to both the nucleus and cytoplasm in Saccharomyces cerevisiae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
CTL1RNA 5’-triphosphatase, localizes to both the nucleus and cytoplasm; Probably involved in an RNA processing event other than mRNA capping. Releases gamma-phosphate from the 5’-end of RNA to produce a diphosphate terminus (320 aa)    
Predicted Functional Partners:
CEG1
Alpha (guanylyltransferase) subunit of the mRNA capping enzyme, a heterodimer (the other subunit is CET1, an RNA 5’-triphosphatase) involved in adding the 5’ cap to mRNA; the mammalian enzyme is a single bifunctional polypeptide; Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5’-end of RNA via an enzyme-GMP covalent reaction intermediate (459 aa)
       
 
  0.702
CBT1
Protein involved in 5’ end processing of mitochondrial COB, 15S_rRNA, and RPM1 transcripts; may also have a role in 3’ end processing of the COB pre-mRNA; displays genetic interaction with cell cycle-regulated kinase Dbf2p; Involved in 5’-end processing of mitochondrial COB, 15S rRNA, and RPM1 transcript. May also have a role in 3’-end processing of the COB pre-mRNA (271 aa)
       
 
  0.649
GRS2
Protein with sequence similarity to Grs1p, which is a glycyl-tRNA synthetase; cannot substitute for Grs1p; possible pseudogene that is expressed at very low levels; Catalyzes the attachment of glycine to tRNA(Gly). Is also able produce diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs (By similarity) (618 aa)
           
  0.519
YGL152C
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF PEX14/YGL153W (225 aa)
           
  0.518
YBR134W
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data (133 aa)
           
  0.518
NUP53
Subunit of the nuclear pore complex (NPC), interacts with karyopherin Kap121p or with Nup170p via overlapping regions of Nup53p, involved in activation of the spindle checkpoint mediated by the Mad1p-Mad2p complex; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transpor [...] (475 aa)
       
      0.507
ABD1
Methyltransferase, catalyzes the transfer of a methyl group from S-adenosylmethionine to the GpppN terminus of capped mRNA; Responsible for methylating the 5’-cap structure of mRNAs (436 aa)
           
  0.487
PRP5
RNA helicase in the DEAD-box family, necessary for prespliceosome formation, bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA; ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (849 aa)
           
  0.470
YKR015C
Putative protein of unknown function (568 aa)
           
  0.448
J0238
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YJL210W/PEX2 (147 aa)
           
  0.444
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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