Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MRPL44Mitochondrial ribosomal protein of the large subunit; protein abundance increases in response to DNA replication stress. (98 aa)    
Predicted Functional Partners:
MRPL37
Mitochondrial ribosomal protein of the large subunit.
   
 
 0.984
MRPL9
Mitochondrial ribosomal protein of the large subunit.
   
 
 0.978
PUF3
mRNA-binding protein PUF3; Protein of the mitochondrial outer surface; links the Arp2/3 complex with the mitochore during anterograde mitochondrial movement; also binds to and promotes degradation of mRNAs for select nuclear-encoded mitochondrial proteins.
    
   0.976
MRPL10
Mitochondrial ribosomal protein of the large subunit; appears as two protein spots (YmL10 and YmL18) on two-dimensional SDS gels.
   
 
 0.974
RSM19
Mitochondrial ribosomal protein of the small subunit; has similarity to E. coli S19 ribosomal protein.
   
 
 0.962
MRPL27
Mitochondrial ribosomal protein of the large subunit; homolog of human Bcl-2 interacting protein BMRP.
   
 
 0.954
MRPS12
37S ribosomal protein S12, mitochondrial; Mitochondrial protein; may interact with ribosomes based on co-purification experiments; similar to E. coli and human mitochondrial S12 ribosomal proteins; Belongs to the universal ribosomal protein uS12 family.
   
 
 0.949
MRPL51
Mitochondrial ribosomal protein of the large subunit.
   
 
 0.939
MRP49
Mitochondrial ribosomal protein of the large subunit; not essential for mitochondrial translation.
   
 
 0.929
MRPS18
Mitochondrial ribosomal protein of the small subunit; essential for viability, unlike most other mitoribosomal proteins.
   
 
 0.911
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: ATCC 18824, Candida robusta, Mycoderma cerevisiae, NRRL Y-12632, S. cerevisiae, Saccharomyces capensis, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, yeast
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.