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YMR226C protein (Saccharomyces cerevisiae) - STRING interaction network
"YMR226C" - NADP(+)-dependent dehydrogenase in Saccharomyces cerevisiae
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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YMR226CNADP(+)-dependent dehydrogenase; acts on serine, L-allo-threonine, and other 3-hydroxy acids; green fluorescent protein fusion protein localizes to the cytoplasm and nucleus; may interact with ribosomes, based on co-purification experiments; NADP-dependent dehydrogenase with broad substrate specificity acting on 3-hydroxy acids. Catalyzes the NADP- dependent oxidation of L-allo-threonine to L-2-amino-3-keto- butyrate, which is spontaneously decarboxylated into aminoacetone. Also acts on D-threonine, L-serine, D-serine, D-3- hydroxyisobutyrate, L-3-hydroxyisobutyrate, D-glycerate and L- [...] (267 aa)    
Predicted Functional Partners:
GLY1
Threonine aldolase, catalyzes the cleavage of L-allo-threonine and L-threonine to glycine; involved in glycine biosynthesis; Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde (387 aa)
     
 
    0.900
TPI1
Triose phosphate isomerase, abundant glycolytic enzyme; mRNA half-life is regulated by iron availability; transcription is controlled by activators Reb1p, Gcr1p, and Rap1p through binding sites in the 5’ non-coding region; inhibition of Tpi1p activi /.../PEP (phosphoenolpyruvate) stimulates redox metabolism in respiring cells; E104D mutation in human TPI causes a rare autosomal disease (248 aa)
       
 
  0.785
TLG1
Essential t-SNARE that forms a complex with Tlg2p and Vti1p and mediates fusion of endosome-derived vesicles with the late Golgi; binds the docking complex VFT (Vps fifty-three) through interaction with Vps51p; SNARE protein (of Qc type) involved in membrane fusion probably in retrograde traffic of cytosolic double-membrane vesicles derived from both, early and possibly late endosomes/PVC (prevacuolar compartment) back to the trans-Golgi network (TGN or late Golgi). It has been reported to function both as a (target membrane) t-SNARE and as a (vesicle) v-SNARE. Upon vesicle tethering t [...] (224 aa)
     
      0.749
YDL114W
Putative short-chain dehydrogenase/reductase; YDL114W is not an essential gene (308 aa)
 
 
 
  0.717
YPR076W
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data (124 aa)
           
  0.698
MPA43
Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies (542 aa)
       
    0.658
YDR109C
Putative kinase (715 aa)
       
    0.658
YBR053C
Putative protein of unknown function; induced by cell wall perturbation (358 aa)
   
 
    0.623
VPS68
Vacuolar membrane protein of unknown function involved in vacuolar protein sorting; also detected in the mitochondria; Involved in vacuolar protein sorting (184 aa)
           
  0.576
YGL039W
Oxidoreductase shown to reduce carbonyl compounds to chiral alcohols (348 aa)
     
 
  0.538
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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