Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
YMR244WUncharacterized protein YMR244W; Putative protein of unknown function; SWAT-GFP fusion protein localizes to the endoplasmic reticulum and vacuole, while mCherry fusion localizes to just the vacuole. (355 aa)    
Predicted Functional Partners:
YER085C
Uncharacterized protein YER085C; Putative protein of unknown function.
   
  
 0.849
YDR042C
Uncharacterized protein YDR042C; Putative protein of unknown function; expression is increased in ssu72-ts69 mutant.
   
  
 0.680
YPR078C
Uncharacterized protein YPR078C; Putative protein of unknown function; possible role in DNA metabolism and/or in genome stability; expression is heat-inducible.
   
  
 0.678
YBR085C-A
Uncharacterized protein YBR085C-A; Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to the nucleus; protein abundance increases in response to DNA replication stress.
      
 0.585
YLL056C
Uncharacterized protein YLL056C; Putative protein of unknown function; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p and genes involved in pleiotropic drug resistance (PDR); expression is induced in cells treated with the mycotoxin patulin; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum and vacuole respectively.
   
  
 0.571
URN1
Pre-mRNA-splicing factor URN1; Protein of unknown function containing WW and FF domains; overexpression causes accumulation of cells in G1 phase.
   
  
 0.563
YGL117W
Uncharacterized protein YGL117W; Putative protein of unknown function.
      
 0.546
JID1
J domain-containing protein 1; Probable Hsp40p co-chaperone; has a DnaJ-like domain and appears to be involved in ER-associated degradation of misfolded proteins containing a tightly folded cytoplasmic domain; inhibits replication of Brome mosaic virus in S. cerevisiae.
   
 
 0.472
AVT4
Vacuolar transporter; exports large neutral amino acids from the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters; localizes to sites of contact between the vacuole and mitochondria (vCLAMPs).
    
 
 0.443
VBA2
Permease of basic amino acids in the vacuolar membrane; Belongs to the major facilitator superfamily.
   
  
 0.438
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: ATCC 18824, Candida robusta, Mycoderma cerevisiae, NRRL Y-12632, S. cerevisiae, Saccharomyces capensis, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, yeast
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