Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
YMR254CUncharacterized protein YMR254C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. (102 aa)    
Predicted Functional Partners:
YDR535C
Putative uncharacterized protein YDR535C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; YDR535C is not an essential gene.
   
    0.508
YHR139C-A
Uncharacterized protein YHR139C-A; Putative protein of unknown function; conserved across S. cerevisiae strains.
   
    0.491
YML084W
Putative uncharacterized protein YML084W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data.
   
    0.475
YMR075C-A
Putative uncharacterized protein YMR075C-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the verified ORF RCO1/YMR075W.
   
    0.475
YBR232C
Putative uncharacterized protein YBR232C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data.
   
    0.456
YMR135W-A
Putative uncharacterized protein YMR135W-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data.
   
    0.410
YER066C-A
Putative uncharacterized protein YER066C-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps uncharacterized ORF YER067W.
   
    0.404
YJL182C
Putative uncharacterized protein YJL182C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps uncharacterized ORF YJL181W.
   
    0.401
YFR056C
Putative uncharacterized protein YFR056C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YFR055W.
   
    0.400
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: ATCC 18824, Candida robusta, Mycoderma cerevisiae, NRRL Y-12632, S. cerevisiae, Saccharomyces capensis, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, yeast
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