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AEP2 protein (Saccharomyces cerevisiae) - STRING interaction network
"AEP2" - Mitochondrial protein, likely involved in translation of the mitochondrial OLI1 mRNA in Saccharomyces cerevisiae
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Predicted Interactions
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textmining
co-expression
protein homology
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AEP2Mitochondrial protein, likely involved in translation of the mitochondrial OLI1 mRNA; exhibits genetic interaction with the OLI1 mRNA 5’-untranslated leader; Required for translation of the mitochondrial OLI1 transcript coding for the mitochondrial ATP synthase subunit 9 (580 aa)    
Predicted Functional Partners:
AEP1
Protein required for expression of the mitochondrial OLI1 gene encoding subunit 9 of F1-F0 ATP synthase; Required for translation of the mitochondrial OLI1 transcript encoding subunit 9 of mitochondrial ATP synthase (518 aa)
     
 
  0.813
ATP22
Specific translational activator for the mitochondrial ATP6 mRNA, encoding a subunit of F1F0 ATP synthase; localized to the mitochondrial inner membrane; Translation factor specific for subunit 6 of the mitochondrial ATPase. Required for assembly of the CF(0) component of the ATPase (684 aa)
     
   
  0.714
AEP3
Peripheral mitochondrial inner membrane protein; may facilitate use of unformylated tRNA-Met in mitochondrial translation initiation; stabilizes the bicistronic AAP1-ATP6 mRNA; Required for respiration. Stabilizes the mitochondrial bicistronic mRNA encoding ATP6 and ATP8, 2 subunits of the proton- translocating ATP synthase (606 aa)
     
   
  0.698
OLI1
F0-ATP synthase subunit c (ATPase-associated proteolipid), encoded on the mitochondrial genome; mutation confers oligomycin resistance; expression is specifically dependent on the nuclear genes AEP1 and AEP2; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, [...] (76 aa)
           
  0.697
YKL131W
Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data (173 aa)
           
  0.680
RMD9
Mitochondrial protein required for respiratory growth; mutant phenotype and genetic interactions suggest a role in delivering mt mRNAs to ribosomes; located on matrix face of the inner membrane and loosely associated with mitoribosomes; Involved in the processing or stability of mitochondrial mRNAs. Required for meiotic nuclear division (646 aa)
           
  0.626
CBP1
Mitochondrial protein that interacts with the 5’-untranslated region of the COB mRNA and has a role in its stability and translation; found in a complex at the inner membrane along with Pet309p; Responsible for conferring a stable 5’-end on cytochrome b mRNA (654 aa)
           
  0.620
ECM12
Putative protein of unknown function; may contribute to cell wall biosynthesis, mutants display zymolyase hypersensitivity; May be involved in cell wall organization and biogenesis (151 aa)
           
  0.573
ATP25
Mitochondrial protein required for the stability of Oli1p (Atp9p) mRNA and for the Oli1p ring formation; YMR098C is not an essential gene; mRNA stabilization factor specific for the 0.95 kb OLI1 mRNA. Also involved in OLI1 ring formation (612 aa)
     
   
  0.523
ATP11
Molecular chaperone, required for the assembly of alpha and beta subunits into the F1 sector of mitochondrial F1F0 ATP synthase; Essential for the assembly of the mitochondrial F1-F0 complex. May interact with the alpha and/or beta subunits of F1- ATPase (318 aa)
     
 
  0.522
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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