node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEP1 | AEP2 | YMR064W | YMR282C | Protein required for expression of the mitochondrial OLI1 gene; mitochondrial OLI1 gene encodes subunit 9 of F1-F0 ATP synthase. | ATPase expression protein 2, mitochondrial; Mitochondrial protein; likely involved in translation of the mitochondrial OLI1 mRNA; exhibits genetic interaction with the OLI1 mRNA 5'-untranslated leader; Belongs to the AEP2 family. | 0.872 |
AEP1 | HRP1 | YMR064W | YOL123W | Protein required for expression of the mitochondrial OLI1 gene; mitochondrial OLI1 gene encodes subunit 9 of F1-F0 ATP synthase. | Nuclear polyadenylated RNA-binding protein 4; Subunit of cleavage factor I; cleavage factor I is a five-subunit complex required for the cleavage and polyadenylation of pre-mRNA 3' ends; RRM-containing heteronuclear RNA binding protein and hnRNPA/B family member that binds to poly (A) signal sequences; required for genome stability. | 0.616 |
AEP1 | OLI1 | YMR064W | Q0130 | Protein required for expression of the mitochondrial OLI1 gene; mitochondrial OLI1 gene encodes subunit 9 of F1-F0 ATP synthase. | F0-ATP synthase subunit c (ATPase-associated proteolipid); encoded on the mitochondrial genome; mutation confers oligomycin resistance; expression is specifically dependent on the nuclear genes AEP1 and AEP2. | 0.510 |
AEP2 | AEP1 | YMR282C | YMR064W | ATPase expression protein 2, mitochondrial; Mitochondrial protein; likely involved in translation of the mitochondrial OLI1 mRNA; exhibits genetic interaction with the OLI1 mRNA 5'-untranslated leader; Belongs to the AEP2 family. | Protein required for expression of the mitochondrial OLI1 gene; mitochondrial OLI1 gene encodes subunit 9 of F1-F0 ATP synthase. | 0.872 |
AEP2 | HRP1 | YMR282C | YOL123W | ATPase expression protein 2, mitochondrial; Mitochondrial protein; likely involved in translation of the mitochondrial OLI1 mRNA; exhibits genetic interaction with the OLI1 mRNA 5'-untranslated leader; Belongs to the AEP2 family. | Nuclear polyadenylated RNA-binding protein 4; Subunit of cleavage factor I; cleavage factor I is a five-subunit complex required for the cleavage and polyadenylation of pre-mRNA 3' ends; RRM-containing heteronuclear RNA binding protein and hnRNPA/B family member that binds to poly (A) signal sequences; required for genome stability. | 0.616 |
AEP2 | ICY1 | YMR282C | YMR195W | ATPase expression protein 2, mitochondrial; Mitochondrial protein; likely involved in translation of the mitochondrial OLI1 mRNA; exhibits genetic interaction with the OLI1 mRNA 5'-untranslated leader; Belongs to the AEP2 family. | Interacting with cytoskeleton protein 1; Protein of unknown function; required for viability in rich media of cells lacking mitochondrial DNA; mutants have an invasive growth defect with elongated morphology; induced by amino acid starvation; ICY1 has a paralog, ICY2, that arose from the whole genome duplication. | 0.638 |
AEP2 | MRS1 | YMR282C | YIR021W | ATPase expression protein 2, mitochondrial; Mitochondrial protein; likely involved in translation of the mitochondrial OLI1 mRNA; exhibits genetic interaction with the OLI1 mRNA 5'-untranslated leader; Belongs to the AEP2 family. | Splicing protein; required for splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA; MRS1 has a paralog, CCE1, that arose from the whole genome duplication. | 0.710 |
AEP2 | OLI1 | YMR282C | Q0130 | ATPase expression protein 2, mitochondrial; Mitochondrial protein; likely involved in translation of the mitochondrial OLI1 mRNA; exhibits genetic interaction with the OLI1 mRNA 5'-untranslated leader; Belongs to the AEP2 family. | F0-ATP synthase subunit c (ATPase-associated proteolipid); encoded on the mitochondrial genome; mutation confers oligomycin resistance; expression is specifically dependent on the nuclear genes AEP1 and AEP2. | 0.889 |
AEP2 | RIT1 | YMR282C | YMR283C | ATPase expression protein 2, mitochondrial; Mitochondrial protein; likely involved in translation of the mitochondrial OLI1 mRNA; exhibits genetic interaction with the OLI1 mRNA 5'-untranslated leader; Belongs to the AEP2 family. | tRNA A64-2'-O-ribosylphosphate transferase; Initiator methionine 2'-O-ribosyl phosphate transferase; modifies the initiator methionine tRNA at position 64 to distinguish it from elongator methionine tRNA. | 0.669 |
AEP2 | YMR031W-A | YMR282C | YMR031W-A | ATPase expression protein 2, mitochondrial; Mitochondrial protein; likely involved in translation of the mitochondrial OLI1 mRNA; exhibits genetic interaction with the OLI1 mRNA 5'-untranslated leader; Belongs to the AEP2 family. | Putative uncharacterized protein YMR031W-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; null mutant displays shortened telomeres; partially overlaps the uncharacterized ORF YMR031C. | 0.698 |
AEP2 | YMR194C-A | YMR282C | YMR194C-A | ATPase expression protein 2, mitochondrial; Mitochondrial protein; likely involved in translation of the mitochondrial OLI1 mRNA; exhibits genetic interaction with the OLI1 mRNA 5'-untranslated leader; Belongs to the AEP2 family. | Putative uncharacterized protein YMR194C-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | 0.630 |
AEP2 | YMR245W | YMR282C | YMR245W | ATPase expression protein 2, mitochondrial; Mitochondrial protein; likely involved in translation of the mitochondrial OLI1 mRNA; exhibits genetic interaction with the OLI1 mRNA 5'-untranslated leader; Belongs to the AEP2 family. | Putative uncharacterized protein YMR245W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | 0.602 |
AEP2 | YMR265C | YMR282C | YMR265C | ATPase expression protein 2, mitochondrial; Mitochondrial protein; likely involved in translation of the mitochondrial OLI1 mRNA; exhibits genetic interaction with the OLI1 mRNA 5'-untranslated leader; Belongs to the AEP2 family. | Uncharacterized protein YMR265C; Putative protein of unknown function. | 0.601 |
HRP1 | AEP1 | YOL123W | YMR064W | Nuclear polyadenylated RNA-binding protein 4; Subunit of cleavage factor I; cleavage factor I is a five-subunit complex required for the cleavage and polyadenylation of pre-mRNA 3' ends; RRM-containing heteronuclear RNA binding protein and hnRNPA/B family member that binds to poly (A) signal sequences; required for genome stability. | Protein required for expression of the mitochondrial OLI1 gene; mitochondrial OLI1 gene encodes subunit 9 of F1-F0 ATP synthase. | 0.616 |
HRP1 | AEP2 | YOL123W | YMR282C | Nuclear polyadenylated RNA-binding protein 4; Subunit of cleavage factor I; cleavage factor I is a five-subunit complex required for the cleavage and polyadenylation of pre-mRNA 3' ends; RRM-containing heteronuclear RNA binding protein and hnRNPA/B family member that binds to poly (A) signal sequences; required for genome stability. | ATPase expression protein 2, mitochondrial; Mitochondrial protein; likely involved in translation of the mitochondrial OLI1 mRNA; exhibits genetic interaction with the OLI1 mRNA 5'-untranslated leader; Belongs to the AEP2 family. | 0.616 |
ICY1 | AEP2 | YMR195W | YMR282C | Interacting with cytoskeleton protein 1; Protein of unknown function; required for viability in rich media of cells lacking mitochondrial DNA; mutants have an invasive growth defect with elongated morphology; induced by amino acid starvation; ICY1 has a paralog, ICY2, that arose from the whole genome duplication. | ATPase expression protein 2, mitochondrial; Mitochondrial protein; likely involved in translation of the mitochondrial OLI1 mRNA; exhibits genetic interaction with the OLI1 mRNA 5'-untranslated leader; Belongs to the AEP2 family. | 0.638 |
ICY1 | RIT1 | YMR195W | YMR283C | Interacting with cytoskeleton protein 1; Protein of unknown function; required for viability in rich media of cells lacking mitochondrial DNA; mutants have an invasive growth defect with elongated morphology; induced by amino acid starvation; ICY1 has a paralog, ICY2, that arose from the whole genome duplication. | tRNA A64-2'-O-ribosylphosphate transferase; Initiator methionine 2'-O-ribosyl phosphate transferase; modifies the initiator methionine tRNA at position 64 to distinguish it from elongator methionine tRNA. | 0.614 |
ICY1 | YMR031W-A | YMR195W | YMR031W-A | Interacting with cytoskeleton protein 1; Protein of unknown function; required for viability in rich media of cells lacking mitochondrial DNA; mutants have an invasive growth defect with elongated morphology; induced by amino acid starvation; ICY1 has a paralog, ICY2, that arose from the whole genome duplication. | Putative uncharacterized protein YMR031W-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; null mutant displays shortened telomeres; partially overlaps the uncharacterized ORF YMR031C. | 0.516 |
ICY1 | YMR194C-A | YMR195W | YMR194C-A | Interacting with cytoskeleton protein 1; Protein of unknown function; required for viability in rich media of cells lacking mitochondrial DNA; mutants have an invasive growth defect with elongated morphology; induced by amino acid starvation; ICY1 has a paralog, ICY2, that arose from the whole genome duplication. | Putative uncharacterized protein YMR194C-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | 0.620 |
ICY1 | YMR245W | YMR195W | YMR245W | Interacting with cytoskeleton protein 1; Protein of unknown function; required for viability in rich media of cells lacking mitochondrial DNA; mutants have an invasive growth defect with elongated morphology; induced by amino acid starvation; ICY1 has a paralog, ICY2, that arose from the whole genome duplication. | Putative uncharacterized protein YMR245W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | 0.558 |