Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
AEP2ATPase expression protein 2, mitochondrial; Mitochondrial protein; likely involved in translation of the mitochondrial OLI1 mRNA; exhibits genetic interaction with the OLI1 mRNA 5'-untranslated leader; Belongs to the AEP2 family. (580 aa)    
Predicted Functional Partners:
AEP1
Protein required for expression of the mitochondrial OLI1 gene; mitochondrial OLI1 gene encodes subunit 9 of F1-F0 ATP synthase.
   
 
 0.999
HRP1
Nuclear polyadenylated RNA-binding protein 4; Subunit of cleavage factor I; cleavage factor I is a five-subunit complex required for the cleavage and polyadenylation of pre-mRNA 3' ends; RRM-containing heteronuclear RNA binding protein and hnRNPA/B family member that binds to poly (A) signal sequences; required for genome stability.
   
   0.896
MRP7
Mitochondrial ribosomal protein of the large subunit.
   
   0.883
ATP25
ATPase synthesis protein 25, mitochondrial; Mitochondrial protein required for the stability of Oli1p (Atp9p) mRNA; also required for the Oli1p ring formation; YMR098C is not an essential gene.
   
 
 0.849
MRPS5
Mitochondrial ribosomal protein of the small subunit.
   
 
 0.848
MRPL10
Mitochondrial ribosomal protein of the large subunit; appears as two protein spots (YmL10 and YmL18) on two-dimensional SDS gels.
   
   0.844
RSM26
Mitochondrial ribosomal protein of the small subunit.
   
   0.841
MRPL15
Mitochondrial ribosomal protein of the large subunit; Belongs to the ribonuclease III family. Mitochondrion- specific ribosomal protein mL57 subfamily.
   
   0.838
MRPS9
Mitochondrial ribosomal protein of the small subunit.
   
 
 0.835
MRPS28
Mitochondrial ribosomal protein of the small subunit.
   
   0.833
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: ATCC 18824, Candida robusta, Mycoderma cerevisiae, NRRL Y-12632, S. cerevisiae, Saccharomyces capensis, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, yeast
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