Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
YNL019CUncharacterized membrane protein YNL019C; Putative protein of unknown function; expression induced during heat stress; YNL019C has a paralog, YNL033W, that arose from a segmental duplication. (284 aa)    
Predicted Functional Partners:
YNL034W
Uncharacterized protein YNL034W; Putative protein of unknown function; not an essential gene; YNL034W has a paralog, YNL018C, that arose from a segmental duplication; To yeast YNL018c.
   
  
 0.934
YNL018C
Putative protein of unknown function; YNL018C has a paralog, YNL034W, that arose from a segmental duplication; To yeast YNL034w.
   
  
 0.922
YNL162W-A
Uncharacterized protein YNL162W-A; Putative protein of unknown function; identified by homology.
      
 0.904
YFL051C
Uncharacterized membrane protein YFL051C; Putative protein of unknown function; SWAT-GFP fusion protein localizes to the cell periphery while mCherry fusion protein localizes to both the cell periphery and vacuole; YFL051C is not an essential gene.
   
  
 0.835
YNL011C
Putative protein of unknown function; YNL011C is not an essential gene.
      
 0.830
YNL095C
Uncharacterized transporter YNL095C; Putative protein of unknown function; predicted to contain a transmembrane domain; not an essential gene; YNL095C has a paralog, ECM3, that arose from the whole genome duplication.
   
  
 0.823
YFL067W
Uncharacterized membrane protein YFL067W; Protein of unknown function; down-regulated at low calcium levels; mCherry fusion protein localizes to the vacuole.
   
  
 0.752
YAL066W
Putative uncharacterized protein YAL066W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data.
   
  
 0.677
SPT15
TATA-binding protein (TBP); general transcription factor that interacts with other factors to form the preinitiation complex at promoters; essential for viability, highly conserved; yeast gene can complement mutations in human homolog TBP.
    
   0.594
GLN4
Glutamine--tRNA ligase; Glutamine tRNA synthetase; monomeric class I tRNA synthetase that catalyzes the specific glutaminylation of tRNA(Gln); N-terminal domain proposed to be involved in enzyme-tRNA interactions; Belongs to the class-I aminoacyl-tRNA synthetase family.
    
   0.591
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: ATCC 18824, Candida robusta, Mycoderma cerevisiae, NRRL Y-12632, S. cerevisiae, Saccharomyces capensis, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, yeast
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