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SIW14 protein (Saccharomyces cerevisiae) - STRING interaction network
"SIW14" - Tyrosine phosphatase involved in actin organization and endocytosis in Saccharomyces cerevisiae
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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SIW14Tyrosine phosphatase involved in actin organization and endocytosis; localized to the cytoplasm; Plays a role in actin filament organization and endocytosis (281 aa)    
Predicted Functional Partners:
OCA4
Cytoplasmic protein required for replication of Brome mosaic virus; S. cerevisiae is a model system for studying replication of positive-strand RNA viruses in their natural hosts; Required for replication of Brome mosaic virus (BMV) (362 aa)
       
 
  0.958
OCA5
Cytoplasmic protein required for replication of Brome mosaic virus; S. cerevisiae is a model system for studying replication of positive-strand RNA viruses in their natural hosts; Required for replication of brome mosaic virus (BMV), a positive-strand RNA virus (679 aa)
       
 
  0.943
OCA2
Putative protein with similarity to predicted tyrosine phosphatases Oca1p and Siw14p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YNL056W is not an essential gene; Required for normal growth in the presence of linoleic acid hydroperoxide (LoaOOH) (197 aa)
     
 
0.896
OCA1
Putative protein tyrosine phosphatase, required for cell cycle arrest in response to oxidative damage of DNA; Putative tyrosine-protein phosphatase required for protection against superoxide stress. Involved in cell-cycle delay in response to linoleic acid hydroperoxide (LoaOOH) (238 aa)
     
 
0.896
PPH21
Catalytic subunit of protein phosphatase 2A (PP2A), functionally redundant with Pph22p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis; Exact function not known, phosphatase 2A performs an essential cellular function (369 aa)
     
 
  0.762
SIT4
Type 2A-related serine-threonine phosphatase that functions in the G1/S transition of the mitotic cycle; cytoplasmic and nuclear protein that modulates functions mediated by Pkc1p including cell wall and actin cytoskeleton organization; Involved in the dephosphorylation of the large subunit of RNA polymerase II. Is required in late G1 for normal G1 cyclin expression, bud initiation and expression of certain genes that are periodically expressed during late G1. Associates with the SAP proteins in a cell cycle-dependent manner (311 aa)
     
 
  0.762
PPH22
Catalytic subunit of protein phosphatase 2A (PP2A), functionally redundant with Pph21p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis; Exact function not known, phosphatase 2A performs an essential cellular function (377 aa)
     
 
  0.760
PPZ1
Serine/threonine protein phosphatase Z, isoform of Ppz2p; involved in regulation of potassium transport, which affects osmotic stability, cell cycle progression, and halotolerance; Essential for the maintenance of cell size and integrity in response to osmotic stress (692 aa)
       
 
  0.718
MPA43
Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies (542 aa)
       
      0.706
OCA6
Cytoplasmic protein required for replication of Brome mosaic virus; S. cerevisiae is a model system for studying positive-strand RNA virus replication; null mutation confers sensitivity to tunicamycin and DTT; Required for replication of Brome mosaic virus (BMV) (224 aa)
       
 
0.622
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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