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YNL035C protein (Saccharomyces cerevisiae) - STRING interaction network
"YNL035C" - Putative protein of unknown function with similarity to proteins containing WD-40 domains in Saccharomyces cerevisiae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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YNL035CPutative protein of unknown function with similarity to proteins containing WD-40 domains; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YNL035C is not an essential gene (389 aa)    
Predicted Functional Partners:
YDR262W
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole and is induced in response to the DNA-damaging agent MMS; gene expression increases in response to Zymoliase treatment (272 aa)
           
  0.836
MIX23
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YBL107C is not an essential gene (196 aa)
           
  0.698
PWP2
Conserved 90S pre-ribosomal component essential for proper endonucleolytic cleavage of the 35 S rRNA precursor at A0, A1, and A2 sites; contains eight WD-repeats; PWP2 deletion leads to defects in cell cycle and bud morphogenesis; Required for bud-site selection and cell separation. Also involved in nucleolar processing of pre-18S ribosomal RNA (923 aa)
     
   
  0.642
MAK5
Essential nucleolar protein, putative DEAD-box RNA helicase required for maintenance of M1 dsRNA virus; involved in biogenesis of large (60S) ribosomal subunits; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs. Required for the maintenance of dsRNA killer plasmid (773 aa)
     
   
  0.570
RRS1
Essential protein that binds ribosomal protein L11; required for nuclear export of the 60S pre-ribosomal subunit during ribosome biogenesis; localizes to the nucleolus and in foci along nuclear periphery; cooperates with Ebp2p and Mps3p to mediate t /.../e clustering by binding Sir4p, but is not involved in telomere tethering; mouse homolog shows altered expression in Huntington’s disease model mice; Required for ribosome biogenesis (203 aa)
     
        0.568
YML133C
Putative Y’ element ATP-dependent helicase; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YML133C contains an intron; Catalyzes DNA unwinding and is involved in telomerase- independent telomere maintenance (1374 aa)
     
   
  0.566
GEX1
Proton-glutathione antiporter localized to the vacuolar and plasma membranes; imports glutathione from the vacuole and exports it through the plasma membrane; has a role in resistance to oxidative stress and modulation of the PKA pathway; Proton/glutathione antiporter that imports glutathione from the vacuole and exports it through the plasma membrane. Involved in resistance to oxidative stress and modulation of the PKA pathway (615 aa)
           
  0.540
NMA111
Serine protease and general molecular chaperone; involved in response to heat stress and promotion of apoptosis; may contribute to lipid homeostasis; sequence similarity to the mammalian Omi/HtrA2 family of serine proteases; Nuclear serine protease which mediates apoptosis through proteolysis of the apoptotic inhibitor BIR1 (997 aa)
     
   
  0.497
NSA1
Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis; Involved in the biogenesis of the 60S ribosomal subunit (463 aa)
     
        0.495
SDS24
One of two S. cerevisiae homologs (Sds23p and Sds24p) of the S. pombe Sds23 protein, which is implicated in APC/cyclosome regulation; involved in cell separation during budding; may play an indirect role in fluid-phase endocytosis; Involved in DNA replication and cell separation during budding (527 aa)
           
  0.489
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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