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OCA2 protein (Saccharomyces cerevisiae) - STRING interaction network
"OCA2" - Putative protein with similarity to predicted tyrosine phosphatases Oca1p and Siw14p in Saccharomyces cerevisiae
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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OCA2Putative protein with similarity to predicted tyrosine phosphatases Oca1p and Siw14p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YNL056W is not an essential gene; Required for normal growth in the presence of linoleic acid hydroperoxide (LoaOOH) (197 aa)    
Predicted Functional Partners:
OCA4
Cytoplasmic protein required for replication of Brome mosaic virus; S. cerevisiae is a model system for studying replication of positive-strand RNA viruses in their natural hosts; Required for replication of Brome mosaic virus (BMV) (362 aa)
       
 
  0.962
OCA5
Cytoplasmic protein required for replication of Brome mosaic virus; S. cerevisiae is a model system for studying replication of positive-strand RNA viruses in their natural hosts; Required for replication of brome mosaic virus (BMV), a positive-strand RNA virus (679 aa)
       
 
  0.936
SIW14
Tyrosine phosphatase involved in actin organization and endocytosis; localized to the cytoplasm; Plays a role in actin filament organization and endocytosis (281 aa)
     
 
0.896
OCA1
Putative protein tyrosine phosphatase, required for cell cycle arrest in response to oxidative damage of DNA; Putative tyrosine-protein phosphatase required for protection against superoxide stress. Involved in cell-cycle delay in response to linoleic acid hydroperoxide (LoaOOH) (238 aa)
       
 
0.890
SKI2
Ski complex component and putative RNA helicase, mediates 3’-5’ RNA degradation by the cytoplasmic exosome; null mutants have superkiller phenotype of increased viral dsRNAs and are synthetic lethal with mutations in 5’-3’ mRNA decay; RNA helicase component of the SKI complex involved in 3’-mRNA degradation pathway. Represses dsRNA virus propagation by specifically blocking translation of viral mRNAs, perhaps recognizing the absence of CAP or poly(A). Essential for cell growth only in the presence of M1 replicon (1287 aa)
       
 
  0.537
PTC4
Cytoplasmic type 2C protein phosphatase (PP2C); identified as a high-copy number suppressor of cnb1 mpk1 synthetic lethality; overexpression decreases high-osmolarity induced Hog1p phosphorylation and kinase activity (393 aa)
     
   
  0.470
PPQ1
Putative protein serine/threonine phosphatase; null mutation enhances efficiency of translational suppressors; Phosphatase involved in the regulation of protein synthesis. Affects translational accuracy (549 aa)
       
 
  0.457
OCA6
Cytoplasmic protein required for replication of Brome mosaic virus; S. cerevisiae is a model system for studying positive-strand RNA virus replication; null mutation confers sensitivity to tunicamycin and DTT; Required for replication of Brome mosaic virus (BMV) (224 aa)
       
 
  0.455
YML009C-A
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data (108 aa)
           
  0.452
YGL042C
Dubious open reading frame, not conserved in closely related Saccharomyces species; deletion mutation blocks replication of Brome mosaic virus in S. cerevisiae, but this is likely due to effects on the overlapping gene DST1 (101 aa)
           
  0.440
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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