| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| OCA1 | OCA2 | YNL099C | YNL056W | Putative protein tyrosine phosphatase; required for cell cycle arrest in response to oxidative damage of DNA. | Tyrosine-protein phosphatase-like protein OCA2; Protein of unknown function; similar to predicted tyrosine phosphatases Oca1p and Siw14p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YNL056W is not an essential gene. | 0.998 |
| OCA1 | OCA4 | YNL099C | YCR095C | Putative protein tyrosine phosphatase; required for cell cycle arrest in response to oxidative damage of DNA. | Cytoplasmic protein required for replication of Brome mosaic virus; S. cerevisiae is a model system for studying replication of positive-strand RNA viruses in their natural hosts. | 0.961 |
| OCA1 | OCA5 | YNL099C | YHL029C | Putative protein tyrosine phosphatase; required for cell cycle arrest in response to oxidative damage of DNA. | Oxidant-induced cell-cycle arrest protein 5; Cytoplasmic protein required for replication of Brome mosaic virus; S. cerevisiae is a model system for studying replication of positive-strand RNA viruses in their natural hosts; Belongs to the OCA5 family. | 0.956 |
| OCA1 | SIW14 | YNL099C | YNL032W | Putative protein tyrosine phosphatase; required for cell cycle arrest in response to oxidative damage of DNA. | Inositol phosphatase SIW14; Tyrosine phosphatase involved in actin organization and endocytosis; localized to the cytoplasm. | 0.998 |
| OCA1 | TDA5 | YNL099C | YLR426W | Putative protein tyrosine phosphatase; required for cell cycle arrest in response to oxidative damage of DNA. | Uncharacterized oxidoreductase TDA5; Putative protein of unknown function; detected in highly purified mitochondria in high-throughput studies; proposed to be involved in resistance to mechlorethamine and streptozotocin; null mutant sensitive to expression of top1-T722A allele; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.585 |
| OCA1 | YAH1 | YNL099C | YPL252C | Putative protein tyrosine phosphatase; required for cell cycle arrest in response to oxidative damage of DNA. | Adrenodoxin homolog, mitochondrial; Ferredoxin of the mitochondrial matrix; required for formation of cellular iron-sulfur proteins; involved in heme A biosynthesis; human homolog FDX1L can complement yeast by allowing growth during down-regulation of yeast YAH1; Belongs to the adrenodoxin/putidaredoxin family. | 0.664 |
| OCA1 | YCR101C | YNL099C | YCR101C | Putative protein tyrosine phosphatase; required for cell cycle arrest in response to oxidative damage of DNA. | Uncharacterized protein YCR101C; Putative protein of unknown function; localizes to the membrane fraction; YCR101C is not an essential gene. | 0.539 |
| OCA1 | YDR132C | YNL099C | YDR132C | Putative protein tyrosine phosphatase; required for cell cycle arrest in response to oxidative damage of DNA. | Uncharacterized protein YDR132C; Protein of unknown function; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; YDR132C has a paralog, YLR108C, that arose from the whole genome duplication. | 0.537 |
| OCA1 | YGL242C | YNL099C | YGL242C | Putative protein tyrosine phosphatase; required for cell cycle arrest in response to oxidative damage of DNA. | Ankyrin repeat-containing protein YGL242C; Protein of unknown function; N-terminally propionylated in vivo; deletion mutant is viable. | 0.548 |
| OCA1 | YPT1 | YNL099C | YFL038C | Putative protein tyrosine phosphatase; required for cell cycle arrest in response to oxidative damage of DNA. | GTP-binding protein YPT1; Rab family GTPase; involved in the ER-to-Golgi step of the secretory pathway; complex formation with the Rab escort protein Mrs6p is required for prenylation of Ypt1p by type II protein geranylgeranyltransferase (Bet2p-Bet4p); binds to unspliced HAC1 mRNA; regulates the unfolded protein response (UPR) by promoting the decay of HAC1 RNA; localizes to the early Golgi, the transitional Golgi and ER membranes, pre-autophagosomal structures, and cytoplasmic vesicles. | 0.760 |
| OCA2 | OCA1 | YNL056W | YNL099C | Tyrosine-protein phosphatase-like protein OCA2; Protein of unknown function; similar to predicted tyrosine phosphatases Oca1p and Siw14p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YNL056W is not an essential gene. | Putative protein tyrosine phosphatase; required for cell cycle arrest in response to oxidative damage of DNA. | 0.998 |
| OCA2 | OCA4 | YNL056W | YCR095C | Tyrosine-protein phosphatase-like protein OCA2; Protein of unknown function; similar to predicted tyrosine phosphatases Oca1p and Siw14p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YNL056W is not an essential gene. | Cytoplasmic protein required for replication of Brome mosaic virus; S. cerevisiae is a model system for studying replication of positive-strand RNA viruses in their natural hosts. | 0.995 |
| OCA2 | OCA5 | YNL056W | YHL029C | Tyrosine-protein phosphatase-like protein OCA2; Protein of unknown function; similar to predicted tyrosine phosphatases Oca1p and Siw14p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YNL056W is not an essential gene. | Oxidant-induced cell-cycle arrest protein 5; Cytoplasmic protein required for replication of Brome mosaic virus; S. cerevisiae is a model system for studying replication of positive-strand RNA viruses in their natural hosts; Belongs to the OCA5 family. | 0.964 |
| OCA2 | SIW14 | YNL056W | YNL032W | Tyrosine-protein phosphatase-like protein OCA2; Protein of unknown function; similar to predicted tyrosine phosphatases Oca1p and Siw14p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YNL056W is not an essential gene. | Inositol phosphatase SIW14; Tyrosine phosphatase involved in actin organization and endocytosis; localized to the cytoplasm. | 0.998 |
| OCA2 | TDA5 | YNL056W | YLR426W | Tyrosine-protein phosphatase-like protein OCA2; Protein of unknown function; similar to predicted tyrosine phosphatases Oca1p and Siw14p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YNL056W is not an essential gene. | Uncharacterized oxidoreductase TDA5; Putative protein of unknown function; detected in highly purified mitochondria in high-throughput studies; proposed to be involved in resistance to mechlorethamine and streptozotocin; null mutant sensitive to expression of top1-T722A allele; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.531 |
| OCA2 | YAH1 | YNL056W | YPL252C | Tyrosine-protein phosphatase-like protein OCA2; Protein of unknown function; similar to predicted tyrosine phosphatases Oca1p and Siw14p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YNL056W is not an essential gene. | Adrenodoxin homolog, mitochondrial; Ferredoxin of the mitochondrial matrix; required for formation of cellular iron-sulfur proteins; involved in heme A biosynthesis; human homolog FDX1L can complement yeast by allowing growth during down-regulation of yeast YAH1; Belongs to the adrenodoxin/putidaredoxin family. | 0.664 |
| OCA2 | YCR101C | YNL056W | YCR101C | Tyrosine-protein phosphatase-like protein OCA2; Protein of unknown function; similar to predicted tyrosine phosphatases Oca1p and Siw14p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YNL056W is not an essential gene. | Uncharacterized protein YCR101C; Putative protein of unknown function; localizes to the membrane fraction; YCR101C is not an essential gene. | 0.475 |
| OCA2 | YDR132C | YNL056W | YDR132C | Tyrosine-protein phosphatase-like protein OCA2; Protein of unknown function; similar to predicted tyrosine phosphatases Oca1p and Siw14p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YNL056W is not an essential gene. | Uncharacterized protein YDR132C; Protein of unknown function; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; YDR132C has a paralog, YLR108C, that arose from the whole genome duplication. | 0.485 |
| OCA2 | YGL242C | YNL056W | YGL242C | Tyrosine-protein phosphatase-like protein OCA2; Protein of unknown function; similar to predicted tyrosine phosphatases Oca1p and Siw14p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YNL056W is not an essential gene. | Ankyrin repeat-containing protein YGL242C; Protein of unknown function; N-terminally propionylated in vivo; deletion mutant is viable. | 0.495 |
| OCA2 | YPT1 | YNL056W | YFL038C | Tyrosine-protein phosphatase-like protein OCA2; Protein of unknown function; similar to predicted tyrosine phosphatases Oca1p and Siw14p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YNL056W is not an essential gene. | GTP-binding protein YPT1; Rab family GTPase; involved in the ER-to-Golgi step of the secretory pathway; complex formation with the Rab escort protein Mrs6p is required for prenylation of Ypt1p by type II protein geranylgeranyltransferase (Bet2p-Bet4p); binds to unspliced HAC1 mRNA; regulates the unfolded protein response (UPR) by promoting the decay of HAC1 RNA; localizes to the early Golgi, the transitional Golgi and ER membranes, pre-autophagosomal structures, and cytoplasmic vesicles. | 0.765 |