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SIP3 protein (Saccharomyces cerevisiae) - STRING interaction network
"SIP3" - Protein that activates transcription through interaction with DNA-bound Snf1p, C-terminal region has a putative leucine zipper motif in Saccharomyces cerevisiae
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second shell of interactors
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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SIP3Protein that activates transcription through interaction with DNA-bound Snf1p, C-terminal region has a putative leucine zipper motif; potential Cdc28p substrate; May be involved in sterol transfer between intracellular membranes (1229 aa)    
Predicted Functional Partners:
SNF1
AMP-activated serine/threonine protein kinase found in a complex containing Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; Essential for release from glucose repression. It interacts and has functional relationship to the regulatory protein SNF4. Could phosphorylate CAT8. Phosphorylates histone H3 to form H3S10ph, which promotes H3K14ac formation, and which is required for transcriptional activation through TBP recruitment to the promoters (633 aa)
     
 
  0.778
YDR114C
Putative protein of unknown function; deletion mutant exhibits poor growth at elevated pH and calcium; May be involved in growth at elevated pH and presence of calcium (100 aa)
           
  0.626
DAL80
Negative regulator of genes in multiple nitrogen degradation pathways; expression is regulated by nitrogen levels and by Gln3p; member of the GATA-binding family, forms homodimers and heterodimers with Deh1p; Negative regulator of multiple nitrogen catabolic genes including the allantoin pathway genes (269 aa)
       
 
  0.559
MRPL23
Mitochondrial ribosomal protein of the large subunit (163 aa)
           
  0.519
EAF3
Esa1p-associated factor, nonessential component of the NuA4 acetyltransferase complex, homologous to Drosophila dosage compensation protein MSL3; plays a role in regulating Ty1 transposition; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (401 aa)
       
      0.507
MKK2
Mitogen-activated kinase kinase involved in protein kinase C signaling pathway that controls cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; Serine/threonine protein kinase involved in a signal transduction pathway that plays a role in yeast cell morphogenesis and cell growth. This pathway seems to start by SMP3; then involves the kinase PKC1 that may act on the BCK1 kinase that then phosphorylates MKK1 and MKK2 which themselves phosphorylate the MPK1 kinase (506 aa)
       
      0.507
MPA43
Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies (542 aa)
           
  0.418
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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