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LTO1 protein (Saccharomyces cerevisiae) - STRING interaction network
"LTO1" - Putative protein of unknown function with similarity to a human protein overexpressed in oral cancers in Saccharomyces cerevisiae
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
LTO1Putative protein of unknown function with similarity to a human protein overexpressed in oral cancers; essential gene with defects in anaerobic and filamentous growth; localizes to the nucleus and cytoplasm (198 aa)    
Predicted Functional Partners:
YAE1
Protein of unknown function, essential for growth under standard (aerobic) conditions but not under anaerobic conditions (141 aa)
       
 
  0.995
RLI1
Essential iron-sulfur protein required for ribosome biogenesis and translation initiation and termination; facilitates binding of a multifactor complex (MFC) of initiation factors to the small ribosomal subunit; predicted ABC family ATPase; Component of the multifactor complex (MFC) involved in translation initiation. Required for the binding of MFC to the 40S ribosome. Required for the processing and nuclear export of the 60S and 40S ribosomal subunits (608 aa)
       
 
  0.827
CIA2
Protein of unknown function required for establishment of sister chromatid cohesion; synthetically lethal with RFC5, an RF-C subunit that links replication to cohesion establishment; YHR122W is an essential gene; May play a role in chromosome segregation through establishment of sister chromatid cohesion (231 aa)
     
 
  0.567
TPT1
tRNA 2’-phosphotransferase that catalyzes final step in tRNA splicing- the transfer of the 2’-PO(4) from the splice junction to NAD(+) to form ADP-ribose 1’’-2’’cyclic phosphate and nicotinamide; Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2’-phosphate from ligated tRNA to NAD to produce ADP-ribose 1’’-2’’ cyclic phosphate (230 aa)
       
      0.541
YJR012C
Essential protein of unknown function; proposed involvement in transport based on mass spectrometry analysis of copurifying proteins; partially overlaps neighboring ORF, GPI14/YJR013W (207 aa)
           
  0.540
RSM10
Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S10 ribosomal protein; essential for viability, unlike most other mitoribosomal proteins; Involved in mitochondrial genome encoded proteins translation. Involved in the binding of tRNA to the ribosomes (By similarity) (203 aa)
           
  0.482
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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