node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BUD16 | BUD17 | YEL029C | YNR027W | Putative pyridoxal kinase; a key enzyme involved in pyridoxal 5'-phosphate synthesis, the active form of vitamin B6; required for genome integrity; involved in bud-site selection; similarity to yeast BUD17 and human pyridoxal kinase (PDXK). | Putative pyridoxal kinase; a key enzyme in vitamin B6 metabolism; involved in bud-site selection; diploid mutants display a random rather than a bipolar budding pattern; similarity to yeast BUD16 and human pyridoxal kinase (PDXK). | 0.951 |
BUD16 | PDX3 | YEL029C | YBR035C | Putative pyridoxal kinase; a key enzyme involved in pyridoxal 5'-phosphate synthesis, the active form of vitamin B6; required for genome integrity; involved in bud-site selection; similarity to yeast BUD17 and human pyridoxal kinase (PDXK). | Pyridoxine (pyridoxamine) phosphate oxidase; has homologs in E. coli and Myxococcus xanthus; transcription is under the general control of nitrogen metabolism; Belongs to the pyridoxamine 5'-phosphate oxidase family. | 0.974 |
BUD16 | SNO3 | YEL029C | YFL060C | Putative pyridoxal kinase; a key enzyme involved in pyridoxal 5'-phosphate synthesis, the active form of vitamin B6; required for genome integrity; involved in bud-site selection; similarity to yeast BUD17 and human pyridoxal kinase (PDXK). | Probable pyridoxal 5'-phosphate synthase subunit SNO3; Protein of unknown function; nearly identical to Sno2p; expression is induced before the diauxic shift and also in the absence of thiamin. | 0.922 |
BUD16 | SNZ2 | YEL029C | YNL333W | Putative pyridoxal kinase; a key enzyme involved in pyridoxal 5'-phosphate synthesis, the active form of vitamin B6; required for genome integrity; involved in bud-site selection; similarity to yeast BUD17 and human pyridoxal kinase (PDXK). | Probable pyridoxal 5'-phosphate synthase subunit SNZ2; Member of a stationary phase-induced gene family; transcription of SNZ2 is induced prior to diauxic shift, and also in the absence of thiamin in a Thi2p-dependent manner; forms a coregulated gene pair with SNO2; interacts with Thi11p. | 0.909 |
BUD16 | THI12 | YEL029C | YNL332W | Putative pyridoxal kinase; a key enzyme involved in pyridoxal 5'-phosphate synthesis, the active form of vitamin B6; required for genome integrity; involved in bud-site selection; similarity to yeast BUD17 and human pyridoxal kinase (PDXK). | 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase THI12; Protein involved in synthesis of the thiamine precursor HMP; member of a subtelomeric gene family including THI5, THI11, THI12, and THI13; hydroxymethylpyrimidine is also known as HMP; Belongs to the NMT1/THI5 family. | 0.871 |
BUD16 | THI20 | YEL029C | YOL055C | Putative pyridoxal kinase; a key enzyme involved in pyridoxal 5'-phosphate synthesis, the active form of vitamin B6; required for genome integrity; involved in bud-site selection; similarity to yeast BUD17 and human pyridoxal kinase (PDXK). | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20; Trifunctional enzyme of thiamine biosynthesis, degradation and salvage; has hydroxymethylpyrimidine (HMP) kinase, HMP-phosphate (HMP-P) kinase and thiaminase activities; member of a gene family with THI21 and THI22; HMP and HMP-P kinase activity redundant with Thi21p; In the C-terminal section; belongs to the thiaminase-2 family. | 0.537 |
BUD16 | THI21 | YEL029C | YPL258C | Putative pyridoxal kinase; a key enzyme involved in pyridoxal 5'-phosphate synthesis, the active form of vitamin B6; required for genome integrity; involved in bud-site selection; similarity to yeast BUD17 and human pyridoxal kinase (PDXK). | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI21; Hydroxymethylpyrimidine (HMP) and HMP-phosphate kinase; involved in thiamine biosynthesis; member of a gene family with THI20 and THI22; functionally redundant with Thi20p; In the C-terminal section; belongs to the thiaminase-2 family. | 0.544 |
BUD16 | YGR017W | YEL029C | YGR017W | Putative pyridoxal kinase; a key enzyme involved in pyridoxal 5'-phosphate synthesis, the active form of vitamin B6; required for genome integrity; involved in bud-site selection; similarity to yeast BUD17 and human pyridoxal kinase (PDXK). | Uncharacterized protein YGR017W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the cytoplasm. | 0.950 |
BUD17 | BUD16 | YNR027W | YEL029C | Putative pyridoxal kinase; a key enzyme in vitamin B6 metabolism; involved in bud-site selection; diploid mutants display a random rather than a bipolar budding pattern; similarity to yeast BUD16 and human pyridoxal kinase (PDXK). | Putative pyridoxal kinase; a key enzyme involved in pyridoxal 5'-phosphate synthesis, the active form of vitamin B6; required for genome integrity; involved in bud-site selection; similarity to yeast BUD17 and human pyridoxal kinase (PDXK). | 0.951 |
BUD17 | PDX3 | YNR027W | YBR035C | Putative pyridoxal kinase; a key enzyme in vitamin B6 metabolism; involved in bud-site selection; diploid mutants display a random rather than a bipolar budding pattern; similarity to yeast BUD16 and human pyridoxal kinase (PDXK). | Pyridoxine (pyridoxamine) phosphate oxidase; has homologs in E. coli and Myxococcus xanthus; transcription is under the general control of nitrogen metabolism; Belongs to the pyridoxamine 5'-phosphate oxidase family. | 0.977 |
BUD17 | SNO3 | YNR027W | YFL060C | Putative pyridoxal kinase; a key enzyme in vitamin B6 metabolism; involved in bud-site selection; diploid mutants display a random rather than a bipolar budding pattern; similarity to yeast BUD16 and human pyridoxal kinase (PDXK). | Probable pyridoxal 5'-phosphate synthase subunit SNO3; Protein of unknown function; nearly identical to Sno2p; expression is induced before the diauxic shift and also in the absence of thiamin. | 0.911 |
BUD17 | SNZ2 | YNR027W | YNL333W | Putative pyridoxal kinase; a key enzyme in vitamin B6 metabolism; involved in bud-site selection; diploid mutants display a random rather than a bipolar budding pattern; similarity to yeast BUD16 and human pyridoxal kinase (PDXK). | Probable pyridoxal 5'-phosphate synthase subunit SNZ2; Member of a stationary phase-induced gene family; transcription of SNZ2 is induced prior to diauxic shift, and also in the absence of thiamin in a Thi2p-dependent manner; forms a coregulated gene pair with SNO2; interacts with Thi11p. | 0.903 |
BUD17 | THI12 | YNR027W | YNL332W | Putative pyridoxal kinase; a key enzyme in vitamin B6 metabolism; involved in bud-site selection; diploid mutants display a random rather than a bipolar budding pattern; similarity to yeast BUD16 and human pyridoxal kinase (PDXK). | 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase THI12; Protein involved in synthesis of the thiamine precursor HMP; member of a subtelomeric gene family including THI5, THI11, THI12, and THI13; hydroxymethylpyrimidine is also known as HMP; Belongs to the NMT1/THI5 family. | 0.800 |
BUD17 | YGR017W | YNR027W | YGR017W | Putative pyridoxal kinase; a key enzyme in vitamin B6 metabolism; involved in bud-site selection; diploid mutants display a random rather than a bipolar budding pattern; similarity to yeast BUD16 and human pyridoxal kinase (PDXK). | Uncharacterized protein YGR017W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the cytoplasm. | 0.950 |
PDX3 | BUD16 | YBR035C | YEL029C | Pyridoxine (pyridoxamine) phosphate oxidase; has homologs in E. coli and Myxococcus xanthus; transcription is under the general control of nitrogen metabolism; Belongs to the pyridoxamine 5'-phosphate oxidase family. | Putative pyridoxal kinase; a key enzyme involved in pyridoxal 5'-phosphate synthesis, the active form of vitamin B6; required for genome integrity; involved in bud-site selection; similarity to yeast BUD17 and human pyridoxal kinase (PDXK). | 0.974 |
PDX3 | BUD17 | YBR035C | YNR027W | Pyridoxine (pyridoxamine) phosphate oxidase; has homologs in E. coli and Myxococcus xanthus; transcription is under the general control of nitrogen metabolism; Belongs to the pyridoxamine 5'-phosphate oxidase family. | Putative pyridoxal kinase; a key enzyme in vitamin B6 metabolism; involved in bud-site selection; diploid mutants display a random rather than a bipolar budding pattern; similarity to yeast BUD16 and human pyridoxal kinase (PDXK). | 0.977 |
PDX3 | SNO3 | YBR035C | YFL060C | Pyridoxine (pyridoxamine) phosphate oxidase; has homologs in E. coli and Myxococcus xanthus; transcription is under the general control of nitrogen metabolism; Belongs to the pyridoxamine 5'-phosphate oxidase family. | Probable pyridoxal 5'-phosphate synthase subunit SNO3; Protein of unknown function; nearly identical to Sno2p; expression is induced before the diauxic shift and also in the absence of thiamin. | 0.935 |
PDX3 | SNZ2 | YBR035C | YNL333W | Pyridoxine (pyridoxamine) phosphate oxidase; has homologs in E. coli and Myxococcus xanthus; transcription is under the general control of nitrogen metabolism; Belongs to the pyridoxamine 5'-phosphate oxidase family. | Probable pyridoxal 5'-phosphate synthase subunit SNZ2; Member of a stationary phase-induced gene family; transcription of SNZ2 is induced prior to diauxic shift, and also in the absence of thiamin in a Thi2p-dependent manner; forms a coregulated gene pair with SNO2; interacts with Thi11p. | 0.962 |
PDX3 | THI12 | YBR035C | YNL332W | Pyridoxine (pyridoxamine) phosphate oxidase; has homologs in E. coli and Myxococcus xanthus; transcription is under the general control of nitrogen metabolism; Belongs to the pyridoxamine 5'-phosphate oxidase family. | 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase THI12; Protein involved in synthesis of the thiamine precursor HMP; member of a subtelomeric gene family including THI5, THI11, THI12, and THI13; hydroxymethylpyrimidine is also known as HMP; Belongs to the NMT1/THI5 family. | 0.856 |
PDX3 | THI20 | YBR035C | YOL055C | Pyridoxine (pyridoxamine) phosphate oxidase; has homologs in E. coli and Myxococcus xanthus; transcription is under the general control of nitrogen metabolism; Belongs to the pyridoxamine 5'-phosphate oxidase family. | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20; Trifunctional enzyme of thiamine biosynthesis, degradation and salvage; has hydroxymethylpyrimidine (HMP) kinase, HMP-phosphate (HMP-P) kinase and thiaminase activities; member of a gene family with THI21 and THI22; HMP and HMP-P kinase activity redundant with Thi21p; In the C-terminal section; belongs to the thiaminase-2 family. | 0.502 |