STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YRF1-6Helicase encoded by the Y' element of subtelomeric regions; highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p (1859 aa)    
Predicted Functional Partners:
YLR464W
Putative uncharacterized protein yel076c-a; Putative protein of unknown function; Belongs to the helicase family. Yeast subtelomeric Y' repeat subfamily
   
   
0.988
YRF1-5
Helicase encoded by the Y' element of subtelomeric regions; highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p
   
  
0.988
YHL050C
Uncharacterized protein YHL050C; Putative protein of unknown function; potential Cdc28p substrate
   
  
0.975
YLL067C
Putative protein of unknown function with similarity to helicases; Putative Y' element ATP-dependent helicase
   
  
0.975
YHR218W
Helicase-like protein encoded within the telomeric Y' element
   
  
0.969
YRF1-4
Y' element ATP-dependent helicase protein 1 copy 4; Helicase encoded by the Y' element of subtelomeric regions; highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p
   
  
0.969
YJL225C
Y' element atp-dependent helicase yjl225c; Catalyzes DNA unwinding and is involved in telomerase- independent telomere maintenance
   
  
0.922
YML133C
Putative Y' element ATP-dependent helicase; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YML133C contains an intron
   
  
0.919
YNL339W-A
Protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
      
 0.918
YNL339W-B
Putative UPF0479 protein YHR219C-A; Protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching; Belongs to the UPF0479 family
      
 0.918
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: ATCC 18824, Candida robusta, NRRL Y-12632, S. cerevisiae, Saccharomyces capensis, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.