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YNR025C protein (Saccharomyces cerevisiae) - STRING interaction network
"YNR025C" - Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data in Saccharomyces cerevisiae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
YNR025CDubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; deletion reduces expression of PIS1 gene encoding phosphatidylinositol synthase (119 aa)    
Predicted Functional Partners:
SDD3
Putative metalloprotease (1037 aa)
           
  0.697
MPP6
Nuclear exosome-associated RNA binding protein; involved in surveillance of pre-rRNAs and pre-mRNAs, and the degradation of cryptic non-coding RNAs (ncRNA); copurifies with ribosomes; Involved in surveillance of pre-rRNAs and pre-mRNAs, and the degradation of cryptic non-coding RNAs (ncRNA) derived from intergenic regions and the ribosomal DNA spacer heterochromatin. Binds RNA (186 aa)
     
   
  0.656
YNL140C
Protein of unknown function; expressed at both mRNA and protein levels; partially overlaps THO2/YNL139C (189 aa)
           
  0.580
SSF2
Protein required for ribosomal large subunit maturation, functionally redundant with Ssf1p; member of the Brix family; Required for biogenesis of the 60S ribosomal subunit (453 aa)
           
  0.576
REX3
RNA exonuclease; required for maturation of the RNA component of RNase MRP; functions redundantly with Rnh70p and Rex2p in processing of U5 snRNA and RNase P RNA; member of RNase D family of exonucleases; 3’ to 5’ exoribonuclease required for proper 3’ end maturation of MRP RNA and of the U5L snRNA (404 aa)
           
  0.518
ALB1
Shuttling pre-60S factor; involved in the biogenesis of ribosomal large subunit; interacts directly with Arx1p; responsible for Tif6p recycling defects in absence of Rei1p; With ARX1, involved in proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit. Accompanies the pre-60S particles to the cytoplasm (175 aa)
           
  0.469
SQS1
Stimulates the ATPase and helicase activities of Prp43p; acts with Prp43p to stimulate 18s rRNA maturation by Nob1p; overexpression antagonizes the suppression of splicing defects by spp382 mutants; component of pre-ribosomal particles; May be involved in splicing since overexpression antagonizes the suppression of splicing defects by SPP382 mutants (767 aa)
           
  0.468
ATP23
Putative metalloprotease of the mitochondrial inner membrane, required for processing of Atp6p; has an additional role in assembly of the F0 sector of the F1F0 ATP synthase complex; Has a dual role in the assembly of mitochondrial ATPase. Acts as a protease that removes the N-terminal 10 residues of mitochondrial ATPase CF(0) subunit 6 (ATP6) at the intermembrane space side. Also involved in the correct assembly of the membrane- embedded ATPase CF(0) particle, probably mediating association of ATP6 with the subunit 9 ring (270 aa)
           
  0.418
NOP13
Nucleolar protein found in preribosomal complexes; contains an RNA recognition motif (RRM) (403 aa)
           
  0.418
RNH70
3’-5’ exoribonuclease; required for maturation of 3’ ends of 5S rRNA and tRNA-Arg3 from dicistronic transcripts; 3’ exoribonuclease required for 5S rRNA maturation and for the proper maturation of the 5’ cistron of the tRNA-Arg3 dicistronic gene. Involved with REX2 in the maturation of the 5.8S rRNA, and with REX2 and REX3, in the 3’ processing of the U5L snRNA (553 aa)
           
  0.418
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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