node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FRE8 | YOL024W | YLR047C | YOL024W | Probable ferric reductase transmembrane component 8; Protein with sequence similarity to iron/copper reductases; involved in iron homeostasis; deletion mutant has iron deficiency/accumulation growth defects; expression increased in the absence of copper-responsive transcription factor Mac1p. | Putative protein of unknown function; predicted to have thiol-disulfide oxidoreductase active site; YOL024W has a paralog, IGD1, that arose from the whole genome duplication. | 0.471 |
GEX1 | YOL024W | YCL073C | YOL024W | Glutathione exchanger 1; Proton:glutathione antiporter; localized to the vacuolar and plasma membranes; imports glutathione from the vacuole and exports it through the plasma membrane; has a role in resistance to oxidative stress and modulation of the PKA pathway; GEX1 has a paralog, GEX2, that arose from a segmental duplication. | Putative protein of unknown function; predicted to have thiol-disulfide oxidoreductase active site; YOL024W has a paralog, IGD1, that arose from the whole genome duplication. | 0.487 |
GTO3 | YOL024W | YMR251W | YOL024W | Glutathione S-transferase omega-like 3; Omega class glutathione transferase; putative cytosolic localization. | Putative protein of unknown function; predicted to have thiol-disulfide oxidoreductase active site; YOL024W has a paralog, IGD1, that arose from the whole genome duplication. | 0.489 |
RCK1 | YOL024W | YGL158W | YOL024W | Serine/threonine-protein kinase RCK1; Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication. | Putative protein of unknown function; predicted to have thiol-disulfide oxidoreductase active site; YOL024W has a paralog, IGD1, that arose from the whole genome duplication. | 0.413 |
YIL134C-A | YJL197C-A | YIL134C-A | YJL197C-A | Uncharacterized protein YIL134C-A; Putative protein of unknown function; identified by fungal homology and RT-PCR. | Uncharacterized protein YJL197C-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the verified gene YJL197C/UBP12. | 0.830 |
YIL134C-A | YJR038C | YIL134C-A | YJR038C | Uncharacterized protein YIL134C-A; Putative protein of unknown function; identified by fungal homology and RT-PCR. | Putative uncharacterized protein YJR038C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | 0.811 |
YIL134C-A | YOL024W | YIL134C-A | YOL024W | Uncharacterized protein YIL134C-A; Putative protein of unknown function; identified by fungal homology and RT-PCR. | Putative protein of unknown function; predicted to have thiol-disulfide oxidoreductase active site; YOL024W has a paralog, IGD1, that arose from the whole genome duplication. | 0.405 |
YJL197C-A | YIL134C-A | YJL197C-A | YIL134C-A | Uncharacterized protein YJL197C-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the verified gene YJL197C/UBP12. | Uncharacterized protein YIL134C-A; Putative protein of unknown function; identified by fungal homology and RT-PCR. | 0.830 |
YJL197C-A | YJR038C | YJL197C-A | YJR038C | Uncharacterized protein YJL197C-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the verified gene YJL197C/UBP12. | Putative uncharacterized protein YJR038C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | 0.816 |
YJL197C-A | YOL024W | YJL197C-A | YOL024W | Uncharacterized protein YJL197C-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the verified gene YJL197C/UBP12. | Putative protein of unknown function; predicted to have thiol-disulfide oxidoreductase active site; YOL024W has a paralog, IGD1, that arose from the whole genome duplication. | 0.406 |
YJR038C | YIL134C-A | YJR038C | YIL134C-A | Putative uncharacterized protein YJR038C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | Uncharacterized protein YIL134C-A; Putative protein of unknown function; identified by fungal homology and RT-PCR. | 0.811 |
YJR038C | YJL197C-A | YJR038C | YJL197C-A | Putative uncharacterized protein YJR038C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | Uncharacterized protein YJL197C-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the verified gene YJL197C/UBP12. | 0.816 |
YJR038C | YOL024W | YJR038C | YOL024W | Putative uncharacterized protein YJR038C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | Putative protein of unknown function; predicted to have thiol-disulfide oxidoreductase active site; YOL024W has a paralog, IGD1, that arose from the whole genome duplication. | 0.409 |
YOL024W | FRE8 | YOL024W | YLR047C | Putative protein of unknown function; predicted to have thiol-disulfide oxidoreductase active site; YOL024W has a paralog, IGD1, that arose from the whole genome duplication. | Probable ferric reductase transmembrane component 8; Protein with sequence similarity to iron/copper reductases; involved in iron homeostasis; deletion mutant has iron deficiency/accumulation growth defects; expression increased in the absence of copper-responsive transcription factor Mac1p. | 0.471 |
YOL024W | GEX1 | YOL024W | YCL073C | Putative protein of unknown function; predicted to have thiol-disulfide oxidoreductase active site; YOL024W has a paralog, IGD1, that arose from the whole genome duplication. | Glutathione exchanger 1; Proton:glutathione antiporter; localized to the vacuolar and plasma membranes; imports glutathione from the vacuole and exports it through the plasma membrane; has a role in resistance to oxidative stress and modulation of the PKA pathway; GEX1 has a paralog, GEX2, that arose from a segmental duplication. | 0.487 |
YOL024W | GTO3 | YOL024W | YMR251W | Putative protein of unknown function; predicted to have thiol-disulfide oxidoreductase active site; YOL024W has a paralog, IGD1, that arose from the whole genome duplication. | Glutathione S-transferase omega-like 3; Omega class glutathione transferase; putative cytosolic localization. | 0.489 |
YOL024W | RCK1 | YOL024W | YGL158W | Putative protein of unknown function; predicted to have thiol-disulfide oxidoreductase active site; YOL024W has a paralog, IGD1, that arose from the whole genome duplication. | Serine/threonine-protein kinase RCK1; Protein kinase involved in oxidative stress response; promotes pseudohyphal growth via activation of Ubp3p phosphorylation; identified as suppressor of S. pombe cell cycle checkpoint mutations; RCK1 has a paralog, RCK2, that arose from the whole genome duplication. | 0.413 |
YOL024W | YIL134C-A | YOL024W | YIL134C-A | Putative protein of unknown function; predicted to have thiol-disulfide oxidoreductase active site; YOL024W has a paralog, IGD1, that arose from the whole genome duplication. | Uncharacterized protein YIL134C-A; Putative protein of unknown function; identified by fungal homology and RT-PCR. | 0.405 |
YOL024W | YJL197C-A | YOL024W | YJL197C-A | Putative protein of unknown function; predicted to have thiol-disulfide oxidoreductase active site; YOL024W has a paralog, IGD1, that arose from the whole genome duplication. | Uncharacterized protein YJL197C-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the verified gene YJL197C/UBP12. | 0.406 |
YOL024W | YJR038C | YOL024W | YJR038C | Putative protein of unknown function; predicted to have thiol-disulfide oxidoreductase active site; YOL024W has a paralog, IGD1, that arose from the whole genome duplication. | Putative uncharacterized protein YJR038C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | 0.409 |