STRINGSTRING
LDS2 protein (Saccharomyces cerevisiae) - STRING interaction network
"LDS2" - Protein of unknown function in Saccharomyces cerevisiae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
Coexpression
Experiments
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[Homology]
Score
LDS2Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; Involved in spore wall assembly (356 aa)    
Predicted Functional Partners:
YDR445C
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data (135 aa)
           
  0.579
KEI1
Component of inositol phosphorylceramide (IPC) synthase; forms a complex with Aur1p and regulates its activity; required for IPC synthase complex localization to the Golgi; post-translationally processed by Kex2p; KEI1 is an essential gene; Regulatory component of the inositol phosphorylceramide (ICP) synthase which catalyzes the addition of a phosphorylinositol group onto ceramide to form inositol phosphorylceramide, an essential step in sphingolipid biosynthesis. Helps the medial Golgi localization of IPC synthase in a COPI vesicle-dependent manner (221 aa)
           
  0.540
YOL079W
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data (132 aa)
           
  0.487
TDA5
Putative protein of unknown function; detected in highly purified mitochondria in high-throughput studies; proposed to be involved in resistance to mechlorethamine and streptozotocin; null mutant sensitive to expression of top1-T722A allele; Involved in the resistance to DNA-damaging agents (326 aa)
           
  0.487
SHE10
Putative glycosylphosphatidylinositol (GPI)-anchored protein of unknown function; overexpression causes growth arrest; Involved in spore wall assembly (PubMed-23966878). May be a component of the mitochondrial RNase MRP (MtMRP), a ribonucleoprotein endoribonuclease involved in the cleaving RNA transcripts to generate primers for DNA replication in mitochondria (PubMed-20086051). Causes growth arrest when highly overexpressed (PubMed-7762298) (577 aa)
           
  0.483
YHR078W
High osmolarity-regulated gene of unknown function (552 aa)
           
  0.483
YPR202W
Putative protein of unknown function with similarity to telomere-encoded helicases; YPR202W is not an essential gene; transcript is predicted to be spliced but there is no evidence that it is spliced in vivo (238 aa)
           
  0.449
YGR226C
Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; overlaps significantly with a verified ORF, AMA1/YGR225W (69 aa)
           
  0.449
YNL050C
Putative protein of unknown function; YNL050c is not an essential gene (270 aa)
           
  0.447
IRC23
Putative protein of unknown function; green fluorescent protein (GFP)-fusion localizes to the ER; null mutant displays increased levels of spontaneous Rad52p foci; Is probably involved in a pathway contributing to genomic integrity (157 aa)
           
  0.441
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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