node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AIM39 | COR1 | YOL053W | YBL045C | Protein of unknown function; null mutant displays elevated frequency of mitochondrial genome loss; Belongs to the AIM39 family. | Core subunit of the ubiquinol-cytochrome c reductase complex; the ubiquinol-cytochrome c reductase complex (bc1 complex) is a component of the mitochondrial inner membrane electron transport chain. | 0.609 |
AIM39 | COX11 | YOL053W | YPL132W | Protein of unknown function; null mutant displays elevated frequency of mitochondrial genome loss; Belongs to the AIM39 family. | Cytochrome c oxidase assembly protein COX11, mitochondrial; Protein required for delivery of copper to Cox1p; mitochondrial inner membrane protein; association with mitochondrial ribosomes suggests that copper delivery may occur during translation of Cox1p; Belongs to the COX11/CtaG family. | 0.557 |
AIM39 | FMP25 | YOL053W | YLR077W | Protein of unknown function; null mutant displays elevated frequency of mitochondrial genome loss; Belongs to the AIM39 family. | Protein FMP25, mitochondrial; Protein required for assembly of respiratory complex III; mitochondrial inner membrane protein; required for an early step in assembly of respiratory complex III (cytochrome bc1 complex); mRNA is targeted to mitochondria. | 0.813 |
AIM39 | PIF1 | YOL053W | YML061C | Protein of unknown function; null mutant displays elevated frequency of mitochondrial genome loss; Belongs to the AIM39 family. | DNA helicase, potent G-quadruplex DNA binder/unwinder; possesses strand annealing activity; promotes DNA synthesis during break-induced replication; important for crossover recombination; translation from different start sites produces mitochondrial and nuclear forms; nuclear form is a catalytic inhibitor of telomerase; mitochondrial form involved in DNA repair and recombination; mutations affect Zn, Fe homeostasis; regulated by Rad53p-dependent phosphorylation in rho0 cells. | 0.434 |
AIM39 | PMP2 | YOL053W | YEL017C-A | Protein of unknown function; null mutant displays elevated frequency of mitochondrial genome loss; Belongs to the AIM39 family. | Proteolipid associated with plasma membrane H(+)-ATPase (Pma1p); regulates plasma membrane H(+)-ATPase activity; protein abundance increases in response to DNA replication stress; PMP2 has a paralog, PMP1, that arose from the whole genome duplication. | 0.412 |
AIM39 | RML2 | YOL053W | YEL050C | Protein of unknown function; null mutant displays elevated frequency of mitochondrial genome loss; Belongs to the AIM39 family. | Mitochondrial ribosomal protein of the large subunit (L2); has similarity to E. coli L2 ribosomal protein; mutant allele (fat21) causes inability to utilize oleate, and induce oleic acid oxidation; may interfere with activity of the Adr1p transcription factor. | 0.715 |
AIM39 | TRM44 | YOL053W | YPL030W | Protein of unknown function; null mutant displays elevated frequency of mitochondrial genome loss; Belongs to the AIM39 family. | tRNA(Ser) Um(44) 2'-O-methyltransferase; involved in maintaining levels of the tRNA-Ser species tS(CGA) and tS(UGA); conserved among metazoans and fungi but there does not appear to be a homolog in plants; TRM44 is a non-essential gene. | 0.412 |
COR1 | AIM39 | YBL045C | YOL053W | Core subunit of the ubiquinol-cytochrome c reductase complex; the ubiquinol-cytochrome c reductase complex (bc1 complex) is a component of the mitochondrial inner membrane electron transport chain. | Protein of unknown function; null mutant displays elevated frequency of mitochondrial genome loss; Belongs to the AIM39 family. | 0.609 |
COR1 | COX11 | YBL045C | YPL132W | Core subunit of the ubiquinol-cytochrome c reductase complex; the ubiquinol-cytochrome c reductase complex (bc1 complex) is a component of the mitochondrial inner membrane electron transport chain. | Cytochrome c oxidase assembly protein COX11, mitochondrial; Protein required for delivery of copper to Cox1p; mitochondrial inner membrane protein; association with mitochondrial ribosomes suggests that copper delivery may occur during translation of Cox1p; Belongs to the COX11/CtaG family. | 0.827 |
COR1 | FMP25 | YBL045C | YLR077W | Core subunit of the ubiquinol-cytochrome c reductase complex; the ubiquinol-cytochrome c reductase complex (bc1 complex) is a component of the mitochondrial inner membrane electron transport chain. | Protein FMP25, mitochondrial; Protein required for assembly of respiratory complex III; mitochondrial inner membrane protein; required for an early step in assembly of respiratory complex III (cytochrome bc1 complex); mRNA is targeted to mitochondria. | 0.627 |
COR1 | RML2 | YBL045C | YEL050C | Core subunit of the ubiquinol-cytochrome c reductase complex; the ubiquinol-cytochrome c reductase complex (bc1 complex) is a component of the mitochondrial inner membrane electron transport chain. | Mitochondrial ribosomal protein of the large subunit (L2); has similarity to E. coli L2 ribosomal protein; mutant allele (fat21) causes inability to utilize oleate, and induce oleic acid oxidation; may interfere with activity of the Adr1p transcription factor. | 0.728 |
COX11 | AIM39 | YPL132W | YOL053W | Cytochrome c oxidase assembly protein COX11, mitochondrial; Protein required for delivery of copper to Cox1p; mitochondrial inner membrane protein; association with mitochondrial ribosomes suggests that copper delivery may occur during translation of Cox1p; Belongs to the COX11/CtaG family. | Protein of unknown function; null mutant displays elevated frequency of mitochondrial genome loss; Belongs to the AIM39 family. | 0.557 |
COX11 | COR1 | YPL132W | YBL045C | Cytochrome c oxidase assembly protein COX11, mitochondrial; Protein required for delivery of copper to Cox1p; mitochondrial inner membrane protein; association with mitochondrial ribosomes suggests that copper delivery may occur during translation of Cox1p; Belongs to the COX11/CtaG family. | Core subunit of the ubiquinol-cytochrome c reductase complex; the ubiquinol-cytochrome c reductase complex (bc1 complex) is a component of the mitochondrial inner membrane electron transport chain. | 0.827 |
COX11 | RML2 | YPL132W | YEL050C | Cytochrome c oxidase assembly protein COX11, mitochondrial; Protein required for delivery of copper to Cox1p; mitochondrial inner membrane protein; association with mitochondrial ribosomes suggests that copper delivery may occur during translation of Cox1p; Belongs to the COX11/CtaG family. | Mitochondrial ribosomal protein of the large subunit (L2); has similarity to E. coli L2 ribosomal protein; mutant allele (fat21) causes inability to utilize oleate, and induce oleic acid oxidation; may interfere with activity of the Adr1p transcription factor. | 0.428 |
FMP25 | AIM39 | YLR077W | YOL053W | Protein FMP25, mitochondrial; Protein required for assembly of respiratory complex III; mitochondrial inner membrane protein; required for an early step in assembly of respiratory complex III (cytochrome bc1 complex); mRNA is targeted to mitochondria. | Protein of unknown function; null mutant displays elevated frequency of mitochondrial genome loss; Belongs to the AIM39 family. | 0.813 |
FMP25 | COR1 | YLR077W | YBL045C | Protein FMP25, mitochondrial; Protein required for assembly of respiratory complex III; mitochondrial inner membrane protein; required for an early step in assembly of respiratory complex III (cytochrome bc1 complex); mRNA is targeted to mitochondria. | Core subunit of the ubiquinol-cytochrome c reductase complex; the ubiquinol-cytochrome c reductase complex (bc1 complex) is a component of the mitochondrial inner membrane electron transport chain. | 0.627 |
FMP25 | RML2 | YLR077W | YEL050C | Protein FMP25, mitochondrial; Protein required for assembly of respiratory complex III; mitochondrial inner membrane protein; required for an early step in assembly of respiratory complex III (cytochrome bc1 complex); mRNA is targeted to mitochondria. | Mitochondrial ribosomal protein of the large subunit (L2); has similarity to E. coli L2 ribosomal protein; mutant allele (fat21) causes inability to utilize oleate, and induce oleic acid oxidation; may interfere with activity of the Adr1p transcription factor. | 0.424 |
PIF1 | AIM39 | YML061C | YOL053W | DNA helicase, potent G-quadruplex DNA binder/unwinder; possesses strand annealing activity; promotes DNA synthesis during break-induced replication; important for crossover recombination; translation from different start sites produces mitochondrial and nuclear forms; nuclear form is a catalytic inhibitor of telomerase; mitochondrial form involved in DNA repair and recombination; mutations affect Zn, Fe homeostasis; regulated by Rad53p-dependent phosphorylation in rho0 cells. | Protein of unknown function; null mutant displays elevated frequency of mitochondrial genome loss; Belongs to the AIM39 family. | 0.434 |
PMP2 | AIM39 | YEL017C-A | YOL053W | Proteolipid associated with plasma membrane H(+)-ATPase (Pma1p); regulates plasma membrane H(+)-ATPase activity; protein abundance increases in response to DNA replication stress; PMP2 has a paralog, PMP1, that arose from the whole genome duplication. | Protein of unknown function; null mutant displays elevated frequency of mitochondrial genome loss; Belongs to the AIM39 family. | 0.412 |
RML2 | AIM39 | YEL050C | YOL053W | Mitochondrial ribosomal protein of the large subunit (L2); has similarity to E. coli L2 ribosomal protein; mutant allele (fat21) causes inability to utilize oleate, and induce oleic acid oxidation; may interfere with activity of the Adr1p transcription factor. | Protein of unknown function; null mutant displays elevated frequency of mitochondrial genome loss; Belongs to the AIM39 family. | 0.715 |