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VPS68 protein (Saccharomyces cerevisiae) - STRING interaction network
"VPS68" - Vacuolar membrane protein of unknown function involved in vacuolar protein sorting in Saccharomyces cerevisiae
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proteins of unknown 3D structure
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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VPS68Vacuolar membrane protein of unknown function involved in vacuolar protein sorting; also detected in the mitochondria; Involved in vacuolar protein sorting (184 aa)    
Predicted Functional Partners:
VPS55
Late endosomal protein involved in late endosome to vacuole transport; functional homolog of human obesity receptor gene-related protein (OB-RGRP); Involved in protein transport from endosomes to the vacuole (140 aa)
     
  0.996
YPR076W
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data (124 aa)
           
  0.748
YMR226C
NADP(+)-dependent dehydrogenase; acts on serine, L-allo-threonine, and other 3-hydroxy acids; green fluorescent protein fusion protein localizes to the cytoplasm and nucleus; may interact with ribosomes, based on co-purification experiments; NADP-dependent dehydrogenase with broad substrate specificity acting on 3-hydroxy acids. Catalyzes the NADP- dependent oxidation of L-allo-threonine to L-2-amino-3-keto- butyrate, which is spontaneously decarboxylated into aminoacetone. Also acts on D-threonine, L-serine, D-serine, D-3- hydroxyisobutyrate, L-3-hydroxyisobutyrate, D-glycerate and L- [...] (267 aa)
           
  0.576
VTA1
Multivesicular body (MVB) protein involved in endosomal protein sorting; regulates Vps4p activity by promoting its oligomerization; has an N-terminal Vps60- and Did2- binding domain, a linker region, and a C-terminal Vps4p binding domain; Has a role in the formation of the multivesicular body (MVB). Required for the sorting of lipids to form intralumenal vesicles and for fluid-phase transport to the vacuole. Required for sorting the plasma membrane proteins STE2 and STE3 into the MVB. Acts a cofactor of VSP4, promotes the oligomerization of VPS4 and stimulates its ATPase activity by 6- [...] (330 aa)
       
 
  0.503
ERR1
Putative phosphopyruvate hydratase (437 aa)
           
  0.489
UBP11
Ubiquitin-specific protease that cleaves ubiquitin from ubiquitinated proteins (717 aa)
           
  0.485
ECM25
Non-essential protein of unknown function; promoter contains a consensus binding sequence for factor Abf1p; May be involved in cell wall organization and biogenesis (599 aa)
           
  0.483
FLC3
Putative FAD transporter, similar to Flc1p and Flc2p; localized to the ER; May be responsible for the transport of FAD into the endoplasmic reticulum lumen, where it is required for oxidative protein folding (802 aa)
           
  0.452
NHX1
Na+/H+ and K+/H+ exchanger, required for intracellular sequestration of Na+ and K+; located in the vacuole and late endosome compartments; required for osmotolerance to acute hypertonic shock and for vacuolar fusion; Endosomal/prevacuolar electroneutral Na(+)/H(+) exchanger which mediates intracellular sequestration of Na(+) cations, regulates vacuolar pH and contributes to osmotolerance following sudden exposure to hyperosmotic media. Contributes also to the postdiauxic/stationary phase resistance to osmotic stress and allows for the continued growth of cells until the acquired osmoto [...] (633 aa)
       
 
  0.440
SFT2
Non-essential tetra-spanning membrane protein found mostly in the late Golgi, can suppress some sed5 alleles; may be part of the transport machinery, but precise function is unknown; similar to mammalian syntaxin 5; Nonessential protein required for the fusion of transport vesicles derived from the endocytic pathway with the Golgi complex. Can be partially replaced by GOT1 (215 aa)
     
   
  0.420
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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