node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NAB6 | YOL159C-A | YML117W | YOL159C-A | Putative RNA-binding protein; associates with mRNAs encoding cell wall proteins in high-throughput studies; deletion mutants display increased sensitivity to some cell wall disrupting agents; expression negatively regulated by cAMP. | Uncharacterized protein YOL159C-A; Protein of unknown function; overexpression affects endocytic protein trafficking; identified by sequence comparison with hemiascomycetous yeast species. | 0.631 |
NAB6 | YPL261C | YML117W | YPL261C | Putative RNA-binding protein; associates with mRNAs encoding cell wall proteins in high-throughput studies; deletion mutants display increased sensitivity to some cell wall disrupting agents; expression negatively regulated by cAMP. | Uncharacterized protein YPL261C; Putative protein of unknown function; conserved among S. cerevisiae strains; YPL261C is not an essential gene; partially overlaps verified ORF YPL260W. | 0.471 |
RBD2 | YHR086W-A | YPL246C | YHR086W-A | Rhomboid protein 2; Possible rhomboid protease; has similarity to eukaryotic rhomboid proteases including Pcp1p. | Uncharacterized protein YHR086W-A; Putative protein of unknown function; identified by fungal homology and RT-PCR; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum and vacuole respectively. | 0.756 |
RBD2 | YOL159C-A | YPL246C | YOL159C-A | Rhomboid protein 2; Possible rhomboid protease; has similarity to eukaryotic rhomboid proteases including Pcp1p. | Uncharacterized protein YOL159C-A; Protein of unknown function; overexpression affects endocytic protein trafficking; identified by sequence comparison with hemiascomycetous yeast species. | 0.691 |
RBD2 | YPL102C | YPL246C | YPL102C | Rhomboid protein 2; Possible rhomboid protease; has similarity to eukaryotic rhomboid proteases including Pcp1p. | Putative uncharacterized protein YPL102C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; not conserved in closely related Saccharomyces species; deletion mutation enhances replication of Brome mosaic virus in S. cerevisiae, but this is likely due to effects on the overlapping gene ELP4. | 0.607 |
RBD2 | YPL261C | YPL246C | YPL261C | Rhomboid protein 2; Possible rhomboid protease; has similarity to eukaryotic rhomboid proteases including Pcp1p. | Uncharacterized protein YPL261C; Putative protein of unknown function; conserved among S. cerevisiae strains; YPL261C is not an essential gene; partially overlaps verified ORF YPL260W. | 0.510 |
SEC59 | YOL159C-A | YMR013C | YOL159C-A | Dolichol kinase; catalyzes the terminal step in dolichyl monophosphate (Dol-P) biosynthesis; required for viability and for normal rates of lipid intermediate synthesis and protein N-glycosylation; Belongs to the polyprenol kinase family. | Uncharacterized protein YOL159C-A; Protein of unknown function; overexpression affects endocytic protein trafficking; identified by sequence comparison with hemiascomycetous yeast species. | 0.612 |
SEC59 | YPL261C | YMR013C | YPL261C | Dolichol kinase; catalyzes the terminal step in dolichyl monophosphate (Dol-P) biosynthesis; required for viability and for normal rates of lipid intermediate synthesis and protein N-glycosylation; Belongs to the polyprenol kinase family. | Uncharacterized protein YPL261C; Putative protein of unknown function; conserved among S. cerevisiae strains; YPL261C is not an essential gene; partially overlaps verified ORF YPL260W. | 0.444 |
SUI3 | YOL159C-A | YPL237W | YOL159C-A | Beta subunit of the translation initiation factor eIF2; involved in the identification of the start codon; proposed to be involved in mRNA binding. | Uncharacterized protein YOL159C-A; Protein of unknown function; overexpression affects endocytic protein trafficking; identified by sequence comparison with hemiascomycetous yeast species. | 0.510 |
YHR086W-A | RBD2 | YHR086W-A | YPL246C | Uncharacterized protein YHR086W-A; Putative protein of unknown function; identified by fungal homology and RT-PCR; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum and vacuole respectively. | Rhomboid protein 2; Possible rhomboid protease; has similarity to eukaryotic rhomboid proteases including Pcp1p. | 0.756 |
YHR086W-A | YOL159C-A | YHR086W-A | YOL159C-A | Uncharacterized protein YHR086W-A; Putative protein of unknown function; identified by fungal homology and RT-PCR; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum and vacuole respectively. | Uncharacterized protein YOL159C-A; Protein of unknown function; overexpression affects endocytic protein trafficking; identified by sequence comparison with hemiascomycetous yeast species. | 0.704 |
YHR086W-A | YPL102C | YHR086W-A | YPL102C | Uncharacterized protein YHR086W-A; Putative protein of unknown function; identified by fungal homology and RT-PCR; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum and vacuole respectively. | Putative uncharacterized protein YPL102C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; not conserved in closely related Saccharomyces species; deletion mutation enhances replication of Brome mosaic virus in S. cerevisiae, but this is likely due to effects on the overlapping gene ELP4. | 0.917 |
YHR086W-A | YPL261C | YHR086W-A | YPL261C | Uncharacterized protein YHR086W-A; Putative protein of unknown function; identified by fungal homology and RT-PCR; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum and vacuole respectively. | Uncharacterized protein YPL261C; Putative protein of unknown function; conserved among S. cerevisiae strains; YPL261C is not an essential gene; partially overlaps verified ORF YPL260W. | 0.561 |
YOL159C-A | NAB6 | YOL159C-A | YML117W | Uncharacterized protein YOL159C-A; Protein of unknown function; overexpression affects endocytic protein trafficking; identified by sequence comparison with hemiascomycetous yeast species. | Putative RNA-binding protein; associates with mRNAs encoding cell wall proteins in high-throughput studies; deletion mutants display increased sensitivity to some cell wall disrupting agents; expression negatively regulated by cAMP. | 0.631 |
YOL159C-A | RBD2 | YOL159C-A | YPL246C | Uncharacterized protein YOL159C-A; Protein of unknown function; overexpression affects endocytic protein trafficking; identified by sequence comparison with hemiascomycetous yeast species. | Rhomboid protein 2; Possible rhomboid protease; has similarity to eukaryotic rhomboid proteases including Pcp1p. | 0.691 |
YOL159C-A | SEC59 | YOL159C-A | YMR013C | Uncharacterized protein YOL159C-A; Protein of unknown function; overexpression affects endocytic protein trafficking; identified by sequence comparison with hemiascomycetous yeast species. | Dolichol kinase; catalyzes the terminal step in dolichyl monophosphate (Dol-P) biosynthesis; required for viability and for normal rates of lipid intermediate synthesis and protein N-glycosylation; Belongs to the polyprenol kinase family. | 0.612 |
YOL159C-A | SUI3 | YOL159C-A | YPL237W | Uncharacterized protein YOL159C-A; Protein of unknown function; overexpression affects endocytic protein trafficking; identified by sequence comparison with hemiascomycetous yeast species. | Beta subunit of the translation initiation factor eIF2; involved in the identification of the start codon; proposed to be involved in mRNA binding. | 0.510 |
YOL159C-A | YHR086W-A | YOL159C-A | YHR086W-A | Uncharacterized protein YOL159C-A; Protein of unknown function; overexpression affects endocytic protein trafficking; identified by sequence comparison with hemiascomycetous yeast species. | Uncharacterized protein YHR086W-A; Putative protein of unknown function; identified by fungal homology and RT-PCR; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum and vacuole respectively. | 0.704 |
YOL159C-A | YPL102C | YOL159C-A | YPL102C | Uncharacterized protein YOL159C-A; Protein of unknown function; overexpression affects endocytic protein trafficking; identified by sequence comparison with hemiascomycetous yeast species. | Putative uncharacterized protein YPL102C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; not conserved in closely related Saccharomyces species; deletion mutation enhances replication of Brome mosaic virus in S. cerevisiae, but this is likely due to effects on the overlapping gene ELP4. | 0.602 |
YOL159C-A | YPL261C | YOL159C-A | YPL261C | Uncharacterized protein YOL159C-A; Protein of unknown function; overexpression affects endocytic protein trafficking; identified by sequence comparison with hemiascomycetous yeast species. | Uncharacterized protein YPL261C; Putative protein of unknown function; conserved among S. cerevisiae strains; YPL261C is not an essential gene; partially overlaps verified ORF YPL260W. | 0.832 |