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KTR1 protein (Saccharomyces cerevisiae) - STRING interaction network
"KTR1" - Alpha-1,2-mannosyltransferase involved in O- and N-linked protein glycosylation in Saccharomyces cerevisiae
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Predicted Interactions
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KTR1Alpha-1,2-mannosyltransferase involved in O- and N-linked protein glycosylation; type II membrane protein; member of the KRE2/MNT1 mannosyltransferase family; Mannosyltransferase that transfers a mannose residue from GDP-mannose to a range of acceptors in vitro (393 aa)    
Predicted Functional Partners:
KRE2
Alpha1,2-mannosyltransferase of the Golgi involved in protein mannosylation; Required for the attachment of the third mannose residue of O-linked saccharides (442 aa)
     
 
0.817
KTR3
Putative alpha-1,2-mannosyltransferase involved in O- and N-linked protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family; Svp26p mediates uptake of Ktr3p into COPII vesicles; Possible glycosyltransferase (404 aa)
         
0.807
MNT3
Alpha-1,3-mannosyltransferase, adds the fourth and fifth alpha-1,3-linked mannose residues to O-linked glycans during protein O-glycosylation; Mannosyltransferase involved in adding the 4th and 5th mannose residues of O-linked glycans (630 aa)
           
  0.697
MNN4
Putative positive regulator of mannosylphosphate transferase (Mnn6p), involved in mannosylphosphorylation of N-linked oligosaccharides; expression increases in late-logarithmic and stationary growth phases; May function as a positive regulator for mannosylphosphate transferase. Is required to mediate mannosylphosphate transfer in both the core and outer chain portions of N-linked oligosaccharides (1178 aa)
           
  0.653
MNN2
Alpha-1,2-mannosyltransferase, responsible for addition of the first alpha-1,2-linked mannose to form the branches on the mannan backbone of oligosaccharides, localizes to an early Golgi compartment; Alpha-1,2-mannosyltransferase, responsible for addition of the first alpha-1,2-linked mannose to form the branches on the mannan backbone of oligosaccharides (597 aa)
     
   
  0.643
MNN5
Alpha-1,2-mannosyltransferase, responsible for addition of the second alpha-1,2-linked mannose of the branches on the mannan backbone of oligosaccharides, localizes to an early Golgi compartment; Responsible for addition of first and second mannose residues to the outer chain of core N-linked polysaccharides and to O-linked mannotriose. Implicated in late Golgi modifications (586 aa)
           
  0.642
MNT2
Mannosyltransferase involved in adding the 4th and 5th mannose residues of O-linked glycans; Mannosyltransferase involved in adding the 4th and 5th mannose residues of O-linked glycans (558 aa)
           
  0.640
MNN1
Alpha-1,3-mannosyltransferase, integral membrane glycoprotein of the Golgi complex, required for addition of alpha1,3-mannose linkages to N-linked and O-linked oligosaccharides, one of five S. cerevisiae proteins of the MNN1 family; Responsible for addition of the terminal mannose residues to the outer chain of core N-linked polysaccharides and to O-linked mannotriose. Implicated in late Golgi modifications (762 aa)
           
  0.638
MNT4
Putative alpha-1,3-mannosyltransferase, not required for protein O-glycosylation (580 aa)
           
  0.626
MNN9
Subunit of Golgi mannosyltransferase complex also containing Anp1p, Mnn10p, Mnn11p, and Hoc1p that mediates elongation of the polysaccharide mannan backbone; forms a separate complex with Van1p that is also involved in backbone elongation; The M-Pol I and M-Pol II complexes possess alpha-1,6- mannosyltransferase activity and are probably involved in the elongation of the mannan backbone of N-linked glycans on cell wall and periplasmic proteins. May also provide alpha-1,2- mannosyltransferase activity to the M-Pol I complex (395 aa)
           
  0.517
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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