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ORT1 protein (Saccharomyces cerevisiae) - STRING interaction network
"ORT1" - Ornithine transporter of the mitochondrial inner membrane, exports ornithine from mitochondria as part of arginine biosynthesis in Saccharomyces cerevisiae
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ORT1Ornithine transporter of the mitochondrial inner membrane, exports ornithine from mitochondria as part of arginine biosynthesis; human ortholog is associated with hyperammonaemia-hyperornithinaemia-homocitrullinuria (HHH) syndrome; Required for arginine biosynthesis. Transports ornithine synthesized from glutamate in the mitochondrial matrix to the cytosol, where it is converted to arginine (292 aa)    
Predicted Functional Partners:
ARG4
Argininosuccinate lyase, catalyzes the final step in the arginine biosynthesis pathway (463 aa)
     
   
  0.871
YGL117W
Putative protein of unknown function (265 aa)
     
        0.853
ARG7
Mitochondrial ornithine acetyltransferase, catalyzes the fifth step in arginine biosynthesis; also possesses acetylglutamate synthase activity, regenerates acetylglutamate while forming ornithine; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis- the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate (441 aa)
     
   
  0.763
RIB5
Riboflavin synthase; catalyzes the last step of the riboflavin biosynthesis pathway; Catalyzes the dismutation of two molecules of 6,7- dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil (238 aa)
     
   
  0.715
GGC1
Mitochondrial GTP/GDP transporter, essential for mitochondrial genome maintenance; has a role in mitochondrial iron transport; member of the mitochondrial carrier family; Mitochondrial GTP/GDP transporter required for GTP uptake and GDP exit from mitochondria. Involved in mitochondrial iron transport and essential for mitochondrial genome maintenance (300 aa)
     
   
  0.676
ARG1
Arginosuccinate synthetase, catalyzes the formation of L-argininosuccinate from citrulline and L-aspartate in the arginine biosynthesis pathway; potential Cdc28p substrate; Catalyzes the eighth step in arginine biosynthesis. Also has a catabolic function as the first enzyme of citrulline utilization as nitrogen source via arginine and the reactions involved in the arginase pathway (420 aa)
     
   
  0.664
TRP3
Indole-3-glycerol-phosphate synthase; forms bifunctional hetero-oligomeric anthranilate synthase-indole-3-glycerol phosphate synthase enzyme complex with Trp2p (484 aa)
     
   
  0.605
YHI9
Protein of unknown function; null mutant is defective in unfolded protein response; possibly involved in a membrane regulation metabolic pathway; member of the PhzF superfamily, though most likely not involved in phenazine production (294 aa)
     
   
  0.604
ADH5
Alcohol dehydrogenase isoenzyme V; involved in ethanol production (351 aa)
     
        0.557
ARG8
Acetylornithine aminotransferase, catalyzes the fourth step in the biosynthesis of the arginine precursor ornithine (423 aa)
     
   
  0.514
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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