node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACT1 | ARP4 | YFL039C | YJL081C | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | Nuclear actin-related protein involved in chromatin remodeling; component of chromatin-remodeling enzyme complexes. | 0.999 |
ACT1 | ARP5 | YFL039C | YNL059C | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | Nuclear actin-related protein involved in chromatin remodeling; component of chromatin-remodeling enzyme complexes; promotes nucleosome shifts in the 3 prime direction; Belongs to the actin family. | 0.988 |
ACT1 | ARP8 | YFL039C | YOR141C | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | Actin-like protein ARP8; Nuclear actin-related protein involved in chromatin remodeling; component of chromatin-remodeling enzyme complexes; has mRNA binding activity. | 0.999 |
ACT1 | IES3 | YFL039C | YLR052W | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | Subunit of the INO80 chromatin remodeling complex. | 0.988 |
ACT1 | IES4 | YFL039C | YOR189W | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | Ino eighty subunit 4; Component of the INO80 chromatiin remodeling complex; target of the Mec1p/Tel1p DNA damage signaling pathway; proposed to link chromatin remodeling to replication checkpoint responses. | 0.999 |
ACT1 | IES6 | YFL039C | YEL044W | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | Chromatin-remodeling complex subunit IES6; Component of the INO80 chromatin remodeling complex; critical for INO80 function; involved in regulation of chromosome segregation and maintenance of normal centromeric chromatin structure; human ortholog INO80C is a member of the human INO80 complex; implicated in DNA repair based on genetic interactions with RAD52 epistasis genes; Belongs to the IES6 family. | 0.972 |
ACT1 | INO80 | YFL039C | YGL150C | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | Chromatin-remodeling ATPase INO80; ATPase and nucleosome spacing factor; subunit of complex containing actin and actin-related proteins that has chromatin remodeling activity and 3' to 5' DNA helicase activity in vitro; promotes nucleosome shifts in the 3 prime direction; has a role in modulating stress gene transcription. | 0.999 |
ACT1 | NHP10 | YFL039C | YDL002C | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | Non-histone protein 10; Non-essential INO80 chromatin remodeling complex subunit; preferentially binds DNA ends, protecting them from exonucleatic cleavage; deletion affects telomere maintenance via recombination; related to mammalian high mobility group proteins. | 0.991 |
ACT1 | RVB1 | YFL039C | YDR190C | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | RuvB-like protein 1; ATP-dependent DNA helicase, also known as pontin; member of the AAA+ and RuvB-like protein families; similar to Rvb2p; conserved component of multiple complexes including the INO80 complex, the Swr1 complex, and the R2TP complex (Rvb1-Rvb2-Tah1-Pih1); involved in multiple processes such as chromatin remodeling, box C/D snoRNP assembly, and RNA polymerase II assembly. | 0.999 |
ACT1 | RVB2 | YFL039C | YPL235W | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | RuvB-like protein 2; ATP-dependent DNA helicase, also known as reptin; member of the AAA+ and RuvB protein families, similar to Rvb1p; conserved component of multiple complexes including the INO80 complex, the Swr1 complex, and the R2TP complex (Rvb1-Rvb2-Tah1-Pih1); involved in multiple processes such as chromatin remodeling, box C/D snoRNP assembly, and RNA polymerase II assembly. | 0.999 |
ARP4 | ACT1 | YJL081C | YFL039C | Nuclear actin-related protein involved in chromatin remodeling; component of chromatin-remodeling enzyme complexes. | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | 0.999 |
ARP4 | ARP5 | YJL081C | YNL059C | Nuclear actin-related protein involved in chromatin remodeling; component of chromatin-remodeling enzyme complexes. | Nuclear actin-related protein involved in chromatin remodeling; component of chromatin-remodeling enzyme complexes; promotes nucleosome shifts in the 3 prime direction; Belongs to the actin family. | 0.997 |
ARP4 | ARP8 | YJL081C | YOR141C | Nuclear actin-related protein involved in chromatin remodeling; component of chromatin-remodeling enzyme complexes. | Actin-like protein ARP8; Nuclear actin-related protein involved in chromatin remodeling; component of chromatin-remodeling enzyme complexes; has mRNA binding activity. | 0.999 |
ARP4 | IES3 | YJL081C | YLR052W | Nuclear actin-related protein involved in chromatin remodeling; component of chromatin-remodeling enzyme complexes. | Subunit of the INO80 chromatin remodeling complex. | 0.991 |
ARP4 | IES4 | YJL081C | YOR189W | Nuclear actin-related protein involved in chromatin remodeling; component of chromatin-remodeling enzyme complexes. | Ino eighty subunit 4; Component of the INO80 chromatiin remodeling complex; target of the Mec1p/Tel1p DNA damage signaling pathway; proposed to link chromatin remodeling to replication checkpoint responses. | 0.999 |
ARP4 | IES6 | YJL081C | YEL044W | Nuclear actin-related protein involved in chromatin remodeling; component of chromatin-remodeling enzyme complexes. | Chromatin-remodeling complex subunit IES6; Component of the INO80 chromatin remodeling complex; critical for INO80 function; involved in regulation of chromosome segregation and maintenance of normal centromeric chromatin structure; human ortholog INO80C is a member of the human INO80 complex; implicated in DNA repair based on genetic interactions with RAD52 epistasis genes; Belongs to the IES6 family. | 0.990 |
ARP4 | INO80 | YJL081C | YGL150C | Nuclear actin-related protein involved in chromatin remodeling; component of chromatin-remodeling enzyme complexes. | Chromatin-remodeling ATPase INO80; ATPase and nucleosome spacing factor; subunit of complex containing actin and actin-related proteins that has chromatin remodeling activity and 3' to 5' DNA helicase activity in vitro; promotes nucleosome shifts in the 3 prime direction; has a role in modulating stress gene transcription. | 0.999 |
ARP4 | NHP10 | YJL081C | YDL002C | Nuclear actin-related protein involved in chromatin remodeling; component of chromatin-remodeling enzyme complexes. | Non-histone protein 10; Non-essential INO80 chromatin remodeling complex subunit; preferentially binds DNA ends, protecting them from exonucleatic cleavage; deletion affects telomere maintenance via recombination; related to mammalian high mobility group proteins. | 0.997 |
ARP4 | RVB1 | YJL081C | YDR190C | Nuclear actin-related protein involved in chromatin remodeling; component of chromatin-remodeling enzyme complexes. | RuvB-like protein 1; ATP-dependent DNA helicase, also known as pontin; member of the AAA+ and RuvB-like protein families; similar to Rvb2p; conserved component of multiple complexes including the INO80 complex, the Swr1 complex, and the R2TP complex (Rvb1-Rvb2-Tah1-Pih1); involved in multiple processes such as chromatin remodeling, box C/D snoRNP assembly, and RNA polymerase II assembly. | 0.999 |
ARP4 | RVB2 | YJL081C | YPL235W | Nuclear actin-related protein involved in chromatin remodeling; component of chromatin-remodeling enzyme complexes. | RuvB-like protein 2; ATP-dependent DNA helicase, also known as reptin; member of the AAA+ and RuvB protein families, similar to Rvb1p; conserved component of multiple complexes including the INO80 complex, the Swr1 complex, and the R2TP complex (Rvb1-Rvb2-Tah1-Pih1); involved in multiple processes such as chromatin remodeling, box C/D snoRNP assembly, and RNA polymerase II assembly. | 0.999 |