node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CSM1 | DSE3 | YCR086W | YOR264W | Monopolin complex subunit CSM1; Nucleolar protein that mediates homolog segregation during meiosis I; forms a complex with Lrs4p and then Mam1p at kinetochores; required for condensin recruitment to the replication fork barrier site and rDNA repeat segregation. | Protein DSE3; Daughter cell-specific protein, may help establish daughter fate; relocalizes from bud neck to cytoplasm upon DNA replication stress. | 0.999 |
CSM1 | MAM1 | YCR086W | YER106W | Monopolin complex subunit CSM1; Nucleolar protein that mediates homolog segregation during meiosis I; forms a complex with Lrs4p and then Mam1p at kinetochores; required for condensin recruitment to the replication fork barrier site and rDNA repeat segregation. | Monopolin complex subunit MAM1; Monopolin; meiosis-specific kinetochore-associated protein involved in monopolar attachment of sister kinetochores to the meiotic spindle; subunit of monopolin, a complex that prevents biorientation of sister kinetochores to ensure homolog biorientation during meiosis I; regulates the conformation, enzyme kinetics and substrate specificity of the Dsn1p kinase, Hrr1p; expressed only during the first meiotic division. | 0.999 |
CTS1 | DSE1 | YLR286C | YER124C | Endochitinase; required for cell separation after mitosis; transcriptional activation during the G1 phase of the cell cycle is mediated by transcription factor Ace2p. | Protein DSE1; Daughter cell-specific protein; may regulate cross-talk between the mating and filamentation pathways; deletion affects cell separation after division and sensitivity to alpha-factor and drugs affecting the cell wall; relocalizes from bud neck to cytoplasm upon DNA replication stress; Belongs to the WD repeat DSE1 family. | 0.930 |
CTS1 | DSE2 | YLR286C | YHR143W | Endochitinase; required for cell separation after mitosis; transcriptional activation during the G1 phase of the cell cycle is mediated by transcription factor Ace2p. | Protein DSE2; Daughter cell-specific secreted protein with similarity to glucanases; degrades cell wall from the daughter side causing daughter to separate from mother; expression is repressed by cAMP. | 0.994 |
CTS1 | DSE3 | YLR286C | YOR264W | Endochitinase; required for cell separation after mitosis; transcriptional activation during the G1 phase of the cell cycle is mediated by transcription factor Ace2p. | Protein DSE3; Daughter cell-specific protein, may help establish daughter fate; relocalizes from bud neck to cytoplasm upon DNA replication stress. | 0.592 |
CTS1 | DSE4 | YLR286C | YNR067C | Endochitinase; required for cell separation after mitosis; transcriptional activation during the G1 phase of the cell cycle is mediated by transcription factor Ace2p. | Endo-1,3(4)-beta-glucanase 1; Daughter cell-specific secreted protein with similarity to glucanases; degrades cell wall from the daughter side causing daughter to separate from mother. | 0.929 |
CTS1 | EGT2 | YLR286C | YNL327W | Endochitinase; required for cell separation after mitosis; transcriptional activation during the G1 phase of the cell cycle is mediated by transcription factor Ace2p. | Protein EGT2; Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase; required for proper cell separation after cytokinesis; expression is activated by Swi5p and tightly regulated in a cell cycle-dependent manner. | 0.967 |
CTS1 | SCW11 | YLR286C | YGL028C | Endochitinase; required for cell separation after mitosis; transcriptional activation during the G1 phase of the cell cycle is mediated by transcription factor Ace2p. | Probable family 17 glucosidase SCW11; Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on its regulation by Ste12p. | 0.955 |
DSE1 | CTS1 | YER124C | YLR286C | Protein DSE1; Daughter cell-specific protein; may regulate cross-talk between the mating and filamentation pathways; deletion affects cell separation after division and sensitivity to alpha-factor and drugs affecting the cell wall; relocalizes from bud neck to cytoplasm upon DNA replication stress; Belongs to the WD repeat DSE1 family. | Endochitinase; required for cell separation after mitosis; transcriptional activation during the G1 phase of the cell cycle is mediated by transcription factor Ace2p. | 0.930 |
DSE1 | DSE2 | YER124C | YHR143W | Protein DSE1; Daughter cell-specific protein; may regulate cross-talk between the mating and filamentation pathways; deletion affects cell separation after division and sensitivity to alpha-factor and drugs affecting the cell wall; relocalizes from bud neck to cytoplasm upon DNA replication stress; Belongs to the WD repeat DSE1 family. | Protein DSE2; Daughter cell-specific secreted protein with similarity to glucanases; degrades cell wall from the daughter side causing daughter to separate from mother; expression is repressed by cAMP. | 0.980 |
DSE1 | DSE3 | YER124C | YOR264W | Protein DSE1; Daughter cell-specific protein; may regulate cross-talk between the mating and filamentation pathways; deletion affects cell separation after division and sensitivity to alpha-factor and drugs affecting the cell wall; relocalizes from bud neck to cytoplasm upon DNA replication stress; Belongs to the WD repeat DSE1 family. | Protein DSE3; Daughter cell-specific protein, may help establish daughter fate; relocalizes from bud neck to cytoplasm upon DNA replication stress. | 0.821 |
DSE1 | DSE4 | YER124C | YNR067C | Protein DSE1; Daughter cell-specific protein; may regulate cross-talk between the mating and filamentation pathways; deletion affects cell separation after division and sensitivity to alpha-factor and drugs affecting the cell wall; relocalizes from bud neck to cytoplasm upon DNA replication stress; Belongs to the WD repeat DSE1 family. | Endo-1,3(4)-beta-glucanase 1; Daughter cell-specific secreted protein with similarity to glucanases; degrades cell wall from the daughter side causing daughter to separate from mother. | 0.918 |
DSE1 | EGT2 | YER124C | YNL327W | Protein DSE1; Daughter cell-specific protein; may regulate cross-talk between the mating and filamentation pathways; deletion affects cell separation after division and sensitivity to alpha-factor and drugs affecting the cell wall; relocalizes from bud neck to cytoplasm upon DNA replication stress; Belongs to the WD repeat DSE1 family. | Protein EGT2; Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase; required for proper cell separation after cytokinesis; expression is activated by Swi5p and tightly regulated in a cell cycle-dependent manner. | 0.925 |
DSE1 | SCW11 | YER124C | YGL028C | Protein DSE1; Daughter cell-specific protein; may regulate cross-talk between the mating and filamentation pathways; deletion affects cell separation after division and sensitivity to alpha-factor and drugs affecting the cell wall; relocalizes from bud neck to cytoplasm upon DNA replication stress; Belongs to the WD repeat DSE1 family. | Probable family 17 glucosidase SCW11; Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on its regulation by Ste12p. | 0.979 |
DSE2 | CTS1 | YHR143W | YLR286C | Protein DSE2; Daughter cell-specific secreted protein with similarity to glucanases; degrades cell wall from the daughter side causing daughter to separate from mother; expression is repressed by cAMP. | Endochitinase; required for cell separation after mitosis; transcriptional activation during the G1 phase of the cell cycle is mediated by transcription factor Ace2p. | 0.994 |
DSE2 | DSE1 | YHR143W | YER124C | Protein DSE2; Daughter cell-specific secreted protein with similarity to glucanases; degrades cell wall from the daughter side causing daughter to separate from mother; expression is repressed by cAMP. | Protein DSE1; Daughter cell-specific protein; may regulate cross-talk between the mating and filamentation pathways; deletion affects cell separation after division and sensitivity to alpha-factor and drugs affecting the cell wall; relocalizes from bud neck to cytoplasm upon DNA replication stress; Belongs to the WD repeat DSE1 family. | 0.980 |
DSE2 | DSE3 | YHR143W | YOR264W | Protein DSE2; Daughter cell-specific secreted protein with similarity to glucanases; degrades cell wall from the daughter side causing daughter to separate from mother; expression is repressed by cAMP. | Protein DSE3; Daughter cell-specific protein, may help establish daughter fate; relocalizes from bud neck to cytoplasm upon DNA replication stress. | 0.790 |
DSE2 | DSE4 | YHR143W | YNR067C | Protein DSE2; Daughter cell-specific secreted protein with similarity to glucanases; degrades cell wall from the daughter side causing daughter to separate from mother; expression is repressed by cAMP. | Endo-1,3(4)-beta-glucanase 1; Daughter cell-specific secreted protein with similarity to glucanases; degrades cell wall from the daughter side causing daughter to separate from mother. | 0.926 |
DSE2 | EGT2 | YHR143W | YNL327W | Protein DSE2; Daughter cell-specific secreted protein with similarity to glucanases; degrades cell wall from the daughter side causing daughter to separate from mother; expression is repressed by cAMP. | Protein EGT2; Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase; required for proper cell separation after cytokinesis; expression is activated by Swi5p and tightly regulated in a cell cycle-dependent manner. | 0.970 |
DSE2 | SCW11 | YHR143W | YGL028C | Protein DSE2; Daughter cell-specific secreted protein with similarity to glucanases; degrades cell wall from the daughter side causing daughter to separate from mother; expression is repressed by cAMP. | Probable family 17 glucosidase SCW11; Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on its regulation by Ste12p. | 0.987 |