STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YOR292CVacuolar membrane protein YOR292C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YOR292C is not an essential gene; Belongs to the peroxisomal membrane protein PXMP2/4 family. (309 aa)    
Predicted Functional Partners:
YIL067C
Uncharacterized protein of unknown function.
      
 0.840
UIP5
Protein of unknown function that interacts with Ulp1p; a Ubl (ubiquitin-like protein)-specific protease for Smt3p protein conjugates.
   
  
 0.832
YNL115C
Uncharacterized vacuolar membrane protein YNL115C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YNL115C is not an essential gene.
   
 
 0.803
YER134C
Magnesium-dependent acid phosphatase; member of the haloacid dehalogenase superfamily; non-essential gene; Belongs to the HAD-like hydrolase superfamily.
      
 0.758
YKL077W
PMA1 stabilization in the Golgi protein 1; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole.
   
  
 0.700
YNR063W
Uncharacterized transcriptional regulatory protein YNR063W; Putative zinc-cluster protein of unknown function.
      
 0.700
DOS2
Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm.
      
 0.692
MRPL24
Mitochondrial ribosomal protein of the large subunit; two mitochondrial ribosomal proteins, YmL14 and YmL24, have been assigned to the same gene.
      
 0.609
LCL1
Long chronological lifespan protein 1; Putative protein of unknown function; deletion mutant is fluconazole resistant and has long chronological lifespan.
   
  
 0.609
GDT1
GCR1-dependent translation factor 1; Calcium transporter localized to the cis- and medial-Golgi apparatus; required for protein glycosylation; GFP-fusion protein localizes to the vacuole; TMEM165, a human gene which causes Congenital Disorders of Glycosylation is orthologous and functionally complements the null allele; expression pattern and physical interactions suggest a possible role in ribosome biogenesis; expression reduced in a gcr1 null mutant; Belongs to the GDT1 family.
   
  
 0.603
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: ATCC 18824, Candida robusta, Mycoderma cerevisiae, NRRL Y-12632, S. cerevisiae, Saccharomyces capensis, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, yeast
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.