node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMF1 | AZR1 | YOR378W | YGR224W | Low affinity NH4+ transporter; member of the DHA2 family of drug:H+ anti porters; putative paralog of ATR1; but not required for boron tolerance; non-essential gene; Belongs to the major facilitator superfamily. | Azole resistance protein 1; Plasma membrane transporter of the major facilitator superfamily; involved in resistance to azole drugs such as ketoconazole and fluconazole. | 0.648 |
AMF1 | HOL1 | YOR378W | YNR055C | Low affinity NH4+ transporter; member of the DHA2 family of drug:H+ anti porters; putative paralog of ATR1; but not required for boron tolerance; non-essential gene; Belongs to the major facilitator superfamily. | Protein HOL1; Putative transporter in the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; mutations in membrane-spanning domains permit cation and histidinol uptake. | 0.624 |
AMF1 | SGE1 | YOR378W | YPR198W | Low affinity NH4+ transporter; member of the DHA2 family of drug:H+ anti porters; putative paralog of ATR1; but not required for boron tolerance; non-essential gene; Belongs to the major facilitator superfamily. | Protein SGE1; Plasma membrane multidrug transporter; member of the major facilitator superfamily; acts as an extrusion permease; partial multicopy suppressor of gal11 mutations. | 0.638 |
AMF1 | VBA2 | YOR378W | YBR293W | Low affinity NH4+ transporter; member of the DHA2 family of drug:H+ anti porters; putative paralog of ATR1; but not required for boron tolerance; non-essential gene; Belongs to the major facilitator superfamily. | Permease of basic amino acids in the vacuolar membrane; Belongs to the major facilitator superfamily. | 0.749 |
AMF1 | VBA3 | YOR378W | YCL069W | Low affinity NH4+ transporter; member of the DHA2 family of drug:H+ anti porters; putative paralog of ATR1; but not required for boron tolerance; non-essential gene; Belongs to the major facilitator superfamily. | Permease of basic amino acids in the vacuolar membrane; VBA3 has a paralog, VBA5, that arose from a segmental duplication; Belongs to the major facilitator superfamily. | 0.689 |
AMF1 | VBA4 | YOR378W | YDR119W | Low affinity NH4+ transporter; member of the DHA2 family of drug:H+ anti porters; putative paralog of ATR1; but not required for boron tolerance; non-essential gene; Belongs to the major facilitator superfamily. | Protein of unknown function; proposed role as a basic amino acid permease based on phylogeny; GFP-fusion protein localizes to vacuolar membrane; physical interaction with Atg27p suggests a possible role in autophagy; non-essential gene; Belongs to the major facilitator superfamily. | 0.702 |
AMF1 | VBA5 | YOR378W | YKR105C | Low affinity NH4+ transporter; member of the DHA2 family of drug:H+ anti porters; putative paralog of ATR1; but not required for boron tolerance; non-essential gene; Belongs to the major facilitator superfamily. | Vacuolar basic amino acid transporter 5; Plasma membrane protein of the Major Facilitator Superfamily (MFS); involved in amino acid uptake and drug sensitivity; VBA5 has a paralog, VBA3, that arose from a segmental duplication. | 0.698 |
AMF1 | YOL097W-A | YOR378W | YOL097W-A | Low affinity NH4+ transporter; member of the DHA2 family of drug:H+ anti porters; putative paralog of ATR1; but not required for boron tolerance; non-essential gene; Belongs to the major facilitator superfamily. | Uncharacterized protein YOL097W-A; Putative protein of unknown function; identified by expression profiling and mass spectrometry. | 0.807 |
AMF1 | YOR365C | YOR378W | YOR365C | Low affinity NH4+ transporter; member of the DHA2 family of drug:H+ anti porters; putative paralog of ATR1; but not required for boron tolerance; non-essential gene; Belongs to the major facilitator superfamily. | Putative protein of unknown function; not an essential protein; YOR365C has a paralog, FLC2, that arose from the whole genome duplication. | 0.780 |
AMF1 | YOR392W | YOR378W | YOR392W | Low affinity NH4+ transporter; member of the DHA2 family of drug:H+ anti porters; putative paralog of ATR1; but not required for boron tolerance; non-essential gene; Belongs to the major facilitator superfamily. | Putative uncharacterized protein YOR392W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; gene expression induced by heat. | 0.804 |
AZR1 | AMF1 | YGR224W | YOR378W | Azole resistance protein 1; Plasma membrane transporter of the major facilitator superfamily; involved in resistance to azole drugs such as ketoconazole and fluconazole. | Low affinity NH4+ transporter; member of the DHA2 family of drug:H+ anti porters; putative paralog of ATR1; but not required for boron tolerance; non-essential gene; Belongs to the major facilitator superfamily. | 0.648 |
AZR1 | HOL1 | YGR224W | YNR055C | Azole resistance protein 1; Plasma membrane transporter of the major facilitator superfamily; involved in resistance to azole drugs such as ketoconazole and fluconazole. | Protein HOL1; Putative transporter in the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; mutations in membrane-spanning domains permit cation and histidinol uptake. | 0.539 |
AZR1 | VBA2 | YGR224W | YBR293W | Azole resistance protein 1; Plasma membrane transporter of the major facilitator superfamily; involved in resistance to azole drugs such as ketoconazole and fluconazole. | Permease of basic amino acids in the vacuolar membrane; Belongs to the major facilitator superfamily. | 0.401 |
HOL1 | AMF1 | YNR055C | YOR378W | Protein HOL1; Putative transporter in the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; mutations in membrane-spanning domains permit cation and histidinol uptake. | Low affinity NH4+ transporter; member of the DHA2 family of drug:H+ anti porters; putative paralog of ATR1; but not required for boron tolerance; non-essential gene; Belongs to the major facilitator superfamily. | 0.624 |
HOL1 | AZR1 | YNR055C | YGR224W | Protein HOL1; Putative transporter in the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; mutations in membrane-spanning domains permit cation and histidinol uptake. | Azole resistance protein 1; Plasma membrane transporter of the major facilitator superfamily; involved in resistance to azole drugs such as ketoconazole and fluconazole. | 0.539 |
HOL1 | VBA3 | YNR055C | YCL069W | Protein HOL1; Putative transporter in the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; mutations in membrane-spanning domains permit cation and histidinol uptake. | Permease of basic amino acids in the vacuolar membrane; VBA3 has a paralog, VBA5, that arose from a segmental duplication; Belongs to the major facilitator superfamily. | 0.411 |
HOL1 | VBA4 | YNR055C | YDR119W | Protein HOL1; Putative transporter in the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; mutations in membrane-spanning domains permit cation and histidinol uptake. | Protein of unknown function; proposed role as a basic amino acid permease based on phylogeny; GFP-fusion protein localizes to vacuolar membrane; physical interaction with Atg27p suggests a possible role in autophagy; non-essential gene; Belongs to the major facilitator superfamily. | 0.514 |
HOL1 | VBA5 | YNR055C | YKR105C | Protein HOL1; Putative transporter in the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; mutations in membrane-spanning domains permit cation and histidinol uptake. | Vacuolar basic amino acid transporter 5; Plasma membrane protein of the Major Facilitator Superfamily (MFS); involved in amino acid uptake and drug sensitivity; VBA5 has a paralog, VBA3, that arose from a segmental duplication. | 0.412 |
SGE1 | AMF1 | YPR198W | YOR378W | Protein SGE1; Plasma membrane multidrug transporter; member of the major facilitator superfamily; acts as an extrusion permease; partial multicopy suppressor of gal11 mutations. | Low affinity NH4+ transporter; member of the DHA2 family of drug:H+ anti porters; putative paralog of ATR1; but not required for boron tolerance; non-essential gene; Belongs to the major facilitator superfamily. | 0.638 |
SGE1 | VBA2 | YPR198W | YBR293W | Protein SGE1; Plasma membrane multidrug transporter; member of the major facilitator superfamily; acts as an extrusion permease; partial multicopy suppressor of gal11 mutations. | Permease of basic amino acids in the vacuolar membrane; Belongs to the major facilitator superfamily. | 0.414 |