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SRL4 protein (Saccharomyces cerevisiae) - STRING interaction network
"SRL4" - Protein of unknown function in Saccharomyces cerevisiae
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
SRL4Protein of unknown function; involved in regulation of dNTP production; null mutant suppresses the lethality of lcd1 and rad53 mutations; expression is induced by Kar4p; May be involved in the regulation of dNTP production. Induces the SOS system when expressed in E.coli, therefore, it may play a role in DNA metabolism and/or in genome stability (281 aa)    
Predicted Functional Partners:
YAL065C
Putative protein of unknown function; has homology to FLO1; possible pseudogene (128 aa)
           
  0.743
CPD1
Cyclic nucleotide phosphodiesterase, hydrolyzes ADP-ribose 1’’, 2’’-cyclic phosphate to ADP-ribose 1’’-phosphate; may have a role in tRNA splicing; no detectable phenotype is conferred by null mutation or by overexpression; Involved in the metabolism of ADP-ribose 1’,2’-cyclic phosphate which is produced as a consequence of tRNA splicing (239 aa)
           
  0.742
YOL118C
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data (102 aa)
           
  0.699
YPR078C
Putative protein of unknown function; possible role in DNA metabolism and/or in genome stability; expression is heat-inducible; Induces the SOS system when expressed in E.coli, therefore, it may play a role in DNA metabolism and/or in genome stability (372 aa)
           
  0.680
GEP5
Protein of unknown function, required for mitochondrial genome maintenance; detected in highly purified mitochondria in high-throughput studies; null mutant has decreased levels of cardiolipin and phosphatidylethanolamine; Essential for respiratory growth and required for maintenance of mtDNA. Required for cell survival in the absence of prohibitins (293 aa)
           
  0.625
YER158C
Protein of unknown function, has similarity to Afr1p; potentially phosphorylated by Cdc28p (573 aa)
           
  0.578
BOP2
Protein of unknown function (570 aa)
           
  0.541
APA1
Diadenosine 5’,5’’-P1,P4-tetraphosphate phosphorylase I (AP4A phosphorylase), involved in catabolism of bis(5’-nucleosidyl) tetraphosphates; has similarity to Apa2p; Ap4A phosphorylase catalyzes the phosphorolytic degradation of bis(5’-adenosyl) tetraphosphate (Ap4A) into ADP and ATP. Can also use other Np4N’ nucleotides (where N and N’ stand for A,C,G or U) as substrates with equal efficiency. Cannot catalyze the reverse reaction. Additionally, this enzyme can also catalyze the phosphorolytic degradation of adenosine 5’- phosphosulfate (AMPS) into ADP and sulfate, the reversible excha [...] (321 aa)
           
  0.540
YHI9
Protein of unknown function; null mutant is defective in unfolded protein response; possibly involved in a membrane regulation metabolic pathway; member of the PhzF superfamily, though most likely not involved in phenazine production (294 aa)
           
  0.517
MTC4
Protein of unknown function, required for normal growth rate at 15 degrees C; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; mtc4 is synthetically sick with cdc13-1 (694 aa)
           
  0.485
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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