node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HFA1 | SWT21 | YMR207C | YNL187W | Acetyl-CoA carboxylase, mitochondrial; Mitochondrial acetyl-coenzyme A carboxylase; catalyzes production of malonyl-CoA in mitochondrial fatty acid biosynthesis; relocalizes from mitochondrion to cytoplasm upon DNA replication stress; genetic and comparative analysis suggests that translation begins at a non-canonical (Ile) start codon at -372 relative to the annotated start codon. | Protein involved in mRNA splicing; contains a consensus nuclear export signal (NES) sequence similar to the consensus sequence recognized by Crm1p; interacts genetically with Prp40p and Tgs1p; contains WD40 repeats. | 0.421 |
HFA1 | YPL034W | YMR207C | YPL034W | Acetyl-CoA carboxylase, mitochondrial; Mitochondrial acetyl-coenzyme A carboxylase; catalyzes production of malonyl-CoA in mitochondrial fatty acid biosynthesis; relocalizes from mitochondrion to cytoplasm upon DNA replication stress; genetic and comparative analysis suggests that translation begins at a non-canonical (Ile) start codon at -372 relative to the annotated start codon. | Putative protein of unknown function; YPL034W is not essential gene. | 0.602 |
LAP3 | YLR126C | YNL239W | YLR126C | Cysteine proteinase 1, mitochondrial; Cysteine aminopeptidase with homocysteine-thiolactonase activity; protects cells against homocysteine toxicity; has bleomycin hydrolase activity in vitro; transcription is regulated by galactose via Gal4p; orthologous to human BLMH; Belongs to the peptidase C1 family. | Putative glutamine amidotransferase; has Aft1p-binding motif in the promoter; may be involved in copper and iron homeostasis; YLR126C is not an essential protein; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress. | 0.428 |
LAP3 | YPL034W | YNL239W | YPL034W | Cysteine proteinase 1, mitochondrial; Cysteine aminopeptidase with homocysteine-thiolactonase activity; protects cells against homocysteine toxicity; has bleomycin hydrolase activity in vitro; transcription is regulated by galactose via Gal4p; orthologous to human BLMH; Belongs to the peptidase C1 family. | Putative protein of unknown function; YPL034W is not essential gene. | 0.554 |
RDS1 | YPL034W | YCR106W | YPL034W | Regulator of drug sensitivity 1; Putative zinc cluster transcription factor; involved in conferring resistance to cycloheximide. | Putative protein of unknown function; YPL034W is not essential gene. | 0.420 |
SWT21 | HFA1 | YNL187W | YMR207C | Protein involved in mRNA splicing; contains a consensus nuclear export signal (NES) sequence similar to the consensus sequence recognized by Crm1p; interacts genetically with Prp40p and Tgs1p; contains WD40 repeats. | Acetyl-CoA carboxylase, mitochondrial; Mitochondrial acetyl-coenzyme A carboxylase; catalyzes production of malonyl-CoA in mitochondrial fatty acid biosynthesis; relocalizes from mitochondrion to cytoplasm upon DNA replication stress; genetic and comparative analysis suggests that translation begins at a non-canonical (Ile) start codon at -372 relative to the annotated start codon. | 0.421 |
SWT21 | YBR012C | YNL187W | YBR012C | Protein involved in mRNA splicing; contains a consensus nuclear export signal (NES) sequence similar to the consensus sequence recognized by Crm1p; interacts genetically with Prp40p and Tgs1p; contains WD40 repeats. | Putative uncharacterized protein YBR012C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; expression induced by iron-regulated transcriptional activator Aft2p. | 0.555 |
SWT21 | YML020W | YNL187W | YML020W | Protein involved in mRNA splicing; contains a consensus nuclear export signal (NES) sequence similar to the consensus sequence recognized by Crm1p; interacts genetically with Prp40p and Tgs1p; contains WD40 repeats. | Uncharacterized protein YML020W; Putative protein of unknown function. | 0.423 |
SWT21 | YPL034W | YNL187W | YPL034W | Protein involved in mRNA splicing; contains a consensus nuclear export signal (NES) sequence similar to the consensus sequence recognized by Crm1p; interacts genetically with Prp40p and Tgs1p; contains WD40 repeats. | Putative protein of unknown function; YPL034W is not essential gene. | 0.831 |
YBR012C | SWT21 | YBR012C | YNL187W | Putative uncharacterized protein YBR012C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; expression induced by iron-regulated transcriptional activator Aft2p. | Protein involved in mRNA splicing; contains a consensus nuclear export signal (NES) sequence similar to the consensus sequence recognized by Crm1p; interacts genetically with Prp40p and Tgs1p; contains WD40 repeats. | 0.555 |
YBR012C | YML020W | YBR012C | YML020W | Putative uncharacterized protein YBR012C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; expression induced by iron-regulated transcriptional activator Aft2p. | Uncharacterized protein YML020W; Putative protein of unknown function. | 0.699 |
YBR012C | YPL034W | YBR012C | YPL034W | Putative uncharacterized protein YBR012C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; expression induced by iron-regulated transcriptional activator Aft2p. | Putative protein of unknown function; YPL034W is not essential gene. | 0.790 |
YLR126C | LAP3 | YLR126C | YNL239W | Putative glutamine amidotransferase; has Aft1p-binding motif in the promoter; may be involved in copper and iron homeostasis; YLR126C is not an essential protein; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress. | Cysteine proteinase 1, mitochondrial; Cysteine aminopeptidase with homocysteine-thiolactonase activity; protects cells against homocysteine toxicity; has bleomycin hydrolase activity in vitro; transcription is regulated by galactose via Gal4p; orthologous to human BLMH; Belongs to the peptidase C1 family. | 0.428 |
YLR126C | YPL034W | YLR126C | YPL034W | Putative glutamine amidotransferase; has Aft1p-binding motif in the promoter; may be involved in copper and iron homeostasis; YLR126C is not an essential protein; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress. | Putative protein of unknown function; YPL034W is not essential gene. | 0.834 |
YML020W | SWT21 | YML020W | YNL187W | Uncharacterized protein YML020W; Putative protein of unknown function. | Protein involved in mRNA splicing; contains a consensus nuclear export signal (NES) sequence similar to the consensus sequence recognized by Crm1p; interacts genetically with Prp40p and Tgs1p; contains WD40 repeats. | 0.423 |
YML020W | YBR012C | YML020W | YBR012C | Uncharacterized protein YML020W; Putative protein of unknown function. | Putative uncharacterized protein YBR012C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; expression induced by iron-regulated transcriptional activator Aft2p. | 0.699 |
YML020W | YPL034W | YML020W | YPL034W | Uncharacterized protein YML020W; Putative protein of unknown function. | Putative protein of unknown function; YPL034W is not essential gene. | 0.609 |
YPL034W | HFA1 | YPL034W | YMR207C | Putative protein of unknown function; YPL034W is not essential gene. | Acetyl-CoA carboxylase, mitochondrial; Mitochondrial acetyl-coenzyme A carboxylase; catalyzes production of malonyl-CoA in mitochondrial fatty acid biosynthesis; relocalizes from mitochondrion to cytoplasm upon DNA replication stress; genetic and comparative analysis suggests that translation begins at a non-canonical (Ile) start codon at -372 relative to the annotated start codon. | 0.602 |
YPL034W | LAP3 | YPL034W | YNL239W | Putative protein of unknown function; YPL034W is not essential gene. | Cysteine proteinase 1, mitochondrial; Cysteine aminopeptidase with homocysteine-thiolactonase activity; protects cells against homocysteine toxicity; has bleomycin hydrolase activity in vitro; transcription is regulated by galactose via Gal4p; orthologous to human BLMH; Belongs to the peptidase C1 family. | 0.554 |
YPL034W | RDS1 | YPL034W | YCR106W | Putative protein of unknown function; YPL034W is not essential gene. | Regulator of drug sensitivity 1; Putative zinc cluster transcription factor; involved in conferring resistance to cycloheximide. | 0.420 |