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KTR6 protein (Saccharomyces cerevisiae) - STRING interaction network
"KTR6" - Probable mannosylphosphate transferase involved in the synthesis of core oligosaccharides in protein glycosylation pathway in Saccharomyces cerevisiae
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KTR6Probable mannosylphosphate transferase involved in the synthesis of core oligosaccharides in protein glycosylation pathway; member of the KRE2/MNT1 mannosyltransferase family; Glycosyltransferase. Required for addition of mannosylphosphate in yeast mannan. Recognizes any oligosaccharides with at least one alpha-1,2-linked mannobiose unit (446 aa)    
Predicted Functional Partners:
MNN1
Alpha-1,3-mannosyltransferase, integral membrane glycoprotein of the Golgi complex, required for addition of alpha1,3-mannose linkages to N-linked and O-linked oligosaccharides, one of five S. cerevisiae proteins of the MNN1 family; Responsible for addition of the terminal mannose residues to the outer chain of core N-linked polysaccharides and to O-linked mannotriose. Implicated in late Golgi modifications (762 aa)
         
  0.983
MNN5
Alpha-1,2-mannosyltransferase, responsible for addition of the second alpha-1,2-linked mannose of the branches on the mannan backbone of oligosaccharides, localizes to an early Golgi compartment; Responsible for addition of first and second mannose residues to the outer chain of core N-linked polysaccharides and to O-linked mannotriose. Implicated in late Golgi modifications (586 aa)
         
  0.974
MNN4
Putative positive regulator of mannosylphosphate transferase (Mnn6p), involved in mannosylphosphorylation of N-linked oligosaccharides; expression increases in late-logarithmic and stationary growth phases; May function as a positive regulator for mannosylphosphate transferase. Is required to mediate mannosylphosphate transfer in both the core and outer chain portions of N-linked oligosaccharides (1178 aa)
           
  0.898
KRE2
Alpha1,2-mannosyltransferase of the Golgi involved in protein mannosylation; Required for the attachment of the third mannose residue of O-linked saccharides (442 aa)
       
 
0.878
MNN2
Alpha-1,2-mannosyltransferase, responsible for addition of the first alpha-1,2-linked mannose to form the branches on the mannan backbone of oligosaccharides, localizes to an early Golgi compartment; Alpha-1,2-mannosyltransferase, responsible for addition of the first alpha-1,2-linked mannose to form the branches on the mannan backbone of oligosaccharides (597 aa)
     
   
  0.764
TOS2
Protein involved in localization of Cdc24p to the site of bud growth; may act as a membrane anchor; localizes to the bud neck and bud tip; potentially phosphorylated by Cdc28p; Seems to be involved in the anchoring of CDC24 to the membrane of polarized growth sites (622 aa)
       
      0.701
MNN9
Subunit of Golgi mannosyltransferase complex also containing Anp1p, Mnn10p, Mnn11p, and Hoc1p that mediates elongation of the polysaccharide mannan backbone; forms a separate complex with Van1p that is also involved in backbone elongation; The M-Pol I and M-Pol II complexes possess alpha-1,6- mannosyltransferase activity and are probably involved in the elongation of the mannan backbone of N-linked glycans on cell wall and periplasmic proteins. May also provide alpha-1,2- mannosyltransferase activity to the M-Pol I complex (395 aa)
           
  0.697
ALG6
Alpha 1,3 glucosyltransferase, involved in transfer of oligosaccharides from dolichyl pyrophosphate to asparagine residues of proteins during N-linked protein glycosylation; mutations in human ortholog are associated with disease; Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol (544 aa)
           
  0.697
HPF1
Haze-protective mannoprotein; reduces the particle size of aggregated proteins in white wines; Involved in cell wall organization and biosynthesis (967 aa)
           
  0.677
VAN1
Component of the mannan polymerase I, which contains Van1p and Mnn9p and is involved in the first steps of mannan synthesis; mutants are vanadate-resistant; Involved in regulation of the phosphorylation of a number of proteins, some of which appear to be important in cell growth control (535 aa)
           
  0.637
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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