STRINGSTRING
LCL1 protein (Saccharomyces cerevisiae) - STRING interaction network
"LCL1" - Putative protein of unknown function in Saccharomyces cerevisiae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LCL1Putative protein of unknown function; deletion mutant is fluconazole resistant and has long chronological lifespan (101 aa)    
Predicted Functional Partners:
LCL2
Putative protein of unknown function; mutant is deficient in amounts of cell wall mannosylphosphate and has long chronological lifespan; genetic interactions suggest a role in ER-associated protein degradation (ERAD); Probable component of the endoplasmic reticulum- associated degradation (ERAD) pathway that acts upstream of HRD3 and USA1 (131 aa)
           
  0.642
YLR407W
Putative protein of unknown function; null mutant displays elongated buds and a large fraction of budded cells have only one nucleus; Deletion results in antifungal drug fluconazole- resistant phenotype (228 aa)
           
  0.579
YLR257W
Putative protein of unknown function (321 aa)
           
  0.520
YOR343C
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data (108 aa)
     
   
  0.517
YDR222W
Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern (415 aa)
           
  0.511
SDD4
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus and is induced in response to the DNA-damaging agent MMS (1133 aa)
           
  0.470
YOL014W
Putative protein of unknown function (124 aa)
           
  0.455
YGR283C
Putative S-adenosylmethionine-dependent methyltransferase; may interact with ribosomes, based on co-purification experiments; predicted to be involved in ribosome biogenesis; null mutant is resistant to fluconazole; GFP-fusion protein localizes to t /.../leolus (341 aa)
           
  0.453
IRC10
Protein of unknown function; null mutant displays increased levels of spontaneous Rad52p foci (586 aa)
           
  0.449
YKR011C
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus (353 aa)
           
  0.416
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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