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YPL088W protein (Saccharomyces cerevisiae) - STRING interaction network
"YPL088W" - Putative aryl alcohol dehydrogenase in Saccharomyces cerevisiae
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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YPL088WPutative aryl alcohol dehydrogenase; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance; Putative aryl-alcohol dehydrogenase (342 aa)    
Predicted Functional Partners:
AAD16
Putative aryl-alcohol dehydrogenase; similar to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role; Putative aryl-alcohol dehydrogenase (152 aa)
       
      0.800
AAD15
Putative aryl-alcohol dehydrogenase; similar to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role; Putative aryl-alcohol dehydrogenase (143 aa)
           
  0.638
YJR096W
Xylose and arabinose reductase; member of the aldo-keto reductase (AKR) family; GFP-fusion protein is induced in response to the DNA-damaging agent MMS (282 aa)
   
   
  0.606
YRR1
Zn2-Cys6 zinc-finger transcription factor that activates genes involved in multidrug resistance; paralog of Yrm1p, acting on an overlapping set of target genes; Transcription factor involved in the regulation of multidrug resistance genes. Acts in concert with YRR1 (810 aa)
           
  0.585
GRE3
Aldose reductase involved in methylglyoxal, d-xylose, arabinose, and galactose metabolism; stress induced (osmotic, ionic, oxidative, heat shock, starvation and heavy metals); regulated by the HOG pathway; Aldose reductase with a broad substrate specificity. Reduces the cytotoxic compound methylglyoxal (MG) to acetol and (R)-lactaldehyde under stress conditions. MG is synthesized via a bypath of glycolysis from dihydroxyacetone phosphate and is believed to play a role in cell cycle regulation and stress adaptation (PubMed-11525399). In pentose-fermenting yeasts, aldose reductase cataly [...] (327 aa)
   
   
  0.528
YLL056C
Putative protein of unknown function, transcription is activated by paralogous transcription factors Yrm1p and Yrr1p and genes involved in pleiotropic drug resistance (PDR); expression is induced in cells treated with the mycotoxin patulin (298 aa)
           
  0.520
CYB2
Cytochrome b2 (L-lactate cytochrome-c oxidoreductase), component of the mitochondrial intermembrane space, required for lactate utilization; expression is repressed by glucose and anaerobic conditions (591 aa)
     
 
  0.503
TOK1
Outward-rectifier potassium channel of the plasma membrane with two pore domains in tandem, each of which forms a functional channel permeable to potassium; carboxy tail functions to prevent inner gate closures; target of K1 toxin; Outwardly rectifying potassium channel (691 aa)
       
 
  0.498
ARA1
NADP+ dependent arabinose dehydrogenase, involved in carbohydrate metabolism; purified as homodimer; naturally occurs with a N-terminus degradation product; Catalyzes the oxidation of D-arabinose, L-xylose, L- fucose and L-galactose in the presence of NADP(+) (344 aa)
   
   
  0.490
YLR179C
Protein of unknown function with similarity to Tfs1p; transcription is activated by paralogous proteins Yrm1p and Yrr1p along with proteins involved in multidrug resistance; GFP-tagged protein localizes to the cytoplasm and nucleus (201 aa)
           
  0.483
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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