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SSU1 protein (Saccharomyces cerevisiae) - STRING interaction network
"SSU1" - Plasma membrane sulfite pump involved in sulfite metabolism in Saccharomyces cerevisiae
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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SSU1Plasma membrane sulfite pump involved in sulfite metabolism; required for efficient sulfite efflux; major facilitator superfamily protein; Involved in efflux of free sulfite. Mutations in the SSU1 gene cause sensitivity to sulfite (458 aa)    
Predicted Functional Partners:
FZF1
Transcription factor involved in sulfite metabolism, sole identified regulatory target is SSU1, overexpression suppresses sulfite-sensitivity of many unrelated mutants due to hyperactivation of SSU1, contains five zinc fingers; May function as a transcription factor (299 aa)
       
 
  0.976
GRR1
F-box protein component of the SCF ubiquitin-ligase complex; involved in carbon catabolite repression, glucose-dependent divalent cation transport, high-affinity glucose transport, morphogenesis, and sulfite detoxification; Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes and directs ubiquitination of phosphorylated CLN1, CLN2 and GIC2. Probably constitutes the primary response element required for the generation or interpretatio [...] (1151 aa)
       
 
  0.912
MET1
S-adenosyl-L-methionine uroporphyrinogen III transmethylase, involved in the biosynthesis of siroheme, a prosthetic group used by sulfite reductase; required for sulfate assimilation and methionine biosynthesis; Siroheme synthase involved in methionine biosynthesis (593 aa)
     
   
  0.837
MET14
Adenylylsulfate kinase, required for sulfate assimilation and involved in methionine metabolism; Catalyzes the synthesis of activated sulfate (202 aa)
       
 
  0.619
YDL186W
Putative protein of unknown function; YDL186W is not an essential gene (277 aa)
           
  0.513
YDR338C
Putative protein of unknown function, member of the multi-drug and toxin extrusion (MATE) family of the multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) exporter superfamily (695 aa)
     
   
  0.508
ECM34
Putative protein of unknown function; member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins; May be involved in cell wall organization and biogenesis (170 aa)
           
  0.485
MET16
3’-phosphoadenylsulfate reductase, reduces 3’-phosphoadenylyl sulfate to adenosine-3’,5’-bisphosphate and free sulfite using reduced thioredoxin as cosubstrate, involved in sulfate assimilation and methionine metabolism; The NADP dependent reduction of PAPS into sulfite involves thioredoxin which probably plays the role of a thiol carrier (261 aa)
           
  0.470
YHB1
Nitric oxide oxidoreductase, flavohemoglobin involved in nitric oxide detoxification; plays a role in the oxidative and nitrosative stress responses; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the fungus from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (399 aa)
   
   
  0.465
MUP1
High affinity methionine permease, integral membrane protein with 13 putative membrane-spanning regions; also involved in cysteine uptake; High affinity permease for methionine (574 aa)
     
   
  0.425
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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