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ENV7 protein (Saccharomyces cerevisiae) - STRING interaction network
"ENV7" - Protein proposed to be involved in vacuolar functions in Saccharomyces cerevisiae
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ENV7Protein proposed to be involved in vacuolar functions; mutant shows defect in CPY processing; has sequence similarity with the human serine/threonine protein kinase STK16; Serine/threonine-protein kinase involved in vacuolar processing and morphology (364 aa)    
Predicted Functional Partners:
YFR006W
Putative X-Pro aminopeptidase; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YFR006W is not an essential gene (535 aa)
       
      0.923
AMD2
Putative amidase (549 aa)
       
      0.753
YCK3
Palmitoylated vacuolar membrane-localized casein kinase I isoform; negatively regulates vacuole fusion during hypertonic stress via phosphorylation of Vps41p; shares essential functions with Hrr25p; regulates vesicle fusion in AP-3 pathway; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates (524 aa)
       
 
  0.699
FRA1
Protein involved in negative regulation of iron regulon transcription; forms an iron independent complex with Fra2p, Grx3p, and Grx4p; cytosolic; mutant fails to repress transcription of iron regulon and is defective in spore formation; Involved in the regulation of the iron regulon in responss to decreased mitochondrial iron-sulfur cluster synthesis (749 aa)
       
      0.691
ICP55
Mitochondrial aminopeptidase; cleaves the N termini of at least 38 imported proteins after cleavage by the mitochondrial processing peptidase (MPP), thereby increasing their stability; member of the aminopeptidase P family; Aminopeptidase which cleaves preprotein intermediates that carry destabilizing N-ter amino acid residues after the mitochondrial processing peptidase (MPP) cleavage site and is thus critical for stabilization of the mitochondrial proteome (511 aa)
       
      0.691
HER2
Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex; involved in the formation of Q-tRNAQ; required for remodeling of ER caused by Hmg2p overexpression; similar to bacterial GatA glutamyl-tRNA amidotransferase; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). Required for HMG2-induced ER-remodeling (464 aa)
       
      0.639
DUR1,2
Urea amidolyase, contains both urea carboxylase and allophanate hydrolase activities, degrades urea to CO2 and NH3; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation; Hydrolysis of urea to ammonia and CO(2) (1835 aa)
       
      0.639
ENV10
Protein proposed to be involved in vacuolar functions; mutant shows defect in CPY processing; YLR065C is not an essential gene; Involved in vacuolar processing and morphology (181 aa)
           
  0.626
PRC1
Vacuolar carboxypeptidase Y (proteinase C, CPY); broad-specificity C-terminal exopeptidase involved in non-specific protein degradation in the vacuole; member of the serine carboxypeptidase family; Involved in degradation of small peptides. Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1’ position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate (532 aa)
       
 
  0.601
IMH1
Protein involved in vesicular transport, mediates transport between an endosomal compartment and the Golgi, contains a Golgi-localization (GRIP) domain that interacts with activated Arl1p-GTP to localize Imh1p to the Golgi; Involved in vesicular transport between an endosomal compartment and the Golgi apparatus (911 aa)
     
   
  0.594
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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