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MDL2 protein (Saccharomyces cerevisiae) - STRING interaction network
"MDL2" - Mitochondrial inner membrane half-type ATP-binding cassette in Saccharomyces cerevisiae
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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MDL2Mitochondrial inner membrane half-type ATP-binding cassette (ABC) transporter, required for respiratory growth at high temperature; similar to human TAP1 and TAP2 implicated in bare lymphocyte syndrome and Wegener-like granulomatosis (773 aa)    
Predicted Functional Partners:
MDL1
Mitochondrial inner membrane half-type ABC transporter; mediates export of peptides generated upon proteolysis of mitochondrial proteins; plays a role in the regulation of cellular resistance to oxidative stress; Mediates export of peptides with molecular masses of 2100 to 600 daltons generated upon proteolysis of mitochondrial inner membrane proteins (695 aa)
   
 
0.914
SAC6
Fimbrin, actin-bundling protein; cooperates with Scp1p (calponin/transgelin) in the organization and maintenance of the actin cytoskeleton; Binds to actin, and functionally associates with actin structures involved in the development and maintenance of cell polarity (642 aa)
       
 
  0.754
BMH1
14-3-3 protein, major isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling; Involved in growth regulation (267 aa)
       
 
  0.750
YPL264C
Putative membrane protein of unknown function; physically interacts with Hsp82p; YPL264C is not an essential gene (353 aa)
       
 
  0.750
HUT1
Protein with a role in UDP-galactose transport to the Golgi lumen, has similarity to human UDP-galactose transporter UGTrel1, exhibits a genetic interaction with S. cerevisiae ERO1; May be involved in specific transport of UDP-Gal from the cytosol to the Golgi lumen. Involved in the maintenance of optimal conditions for the folding of secretory pathway proteins in the endoplasmic reticulum. Overexpression confers resistance to the immunosuppressive drug, leflunomide (339 aa)
       
 
  0.750
YMR253C
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; YMR253C is not an essential gene (414 aa)
       
 
  0.750
YMD8
Putative nucleotide sugar transporter, has similarity to Vrg4p (442 aa)
       
 
  0.750
YML018C
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the membrane of the vacuole; physical interaction with Atg27p suggests a possible role in autophagy; YML018C is not an essential gene (393 aa)
       
 
  0.750
THI74
Mitochondrial transporter repressible by thiamine; May be involved in thiaminediphosphate transport across the mitochondrial membrane (370 aa)
       
 
  0.750
BMH2
14-3-3 protein, minor isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling (273 aa)
       
      0.744
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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