node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABM1 | IRC10 | YJR108W | YOL015W | Aberrant microtubules protein 1; Protein of unknown function; required for normal microtubule organization. | Uncharacterized protein IRC10; Protein of unknown function; subunit of the leading edge protein (LEP) complex (Ssp1-Ady3-Don1-Irc10) that forms a ring-like structure at the leading edge of the prospore membrane during meiosis II; null mutant displays increased levels of spontaneous Rad52p foci. | 0.603 |
ABM1 | YLR146W-A | YJR108W | YLR146W-A | Aberrant microtubules protein 1; Protein of unknown function; required for normal microtubule organization. | Coiled-coil domain-containing protein YLR146W-A; Putative protein of unknown function. | 0.460 |
ABM1 | YPR071W | YJR108W | YPR071W | Aberrant microtubules protein 1; Protein of unknown function; required for normal microtubule organization. | Putative membrane protein; YPR071W is not an essential gene; YPR071W has a paralog, YIL029C, that arose from a single-locus duplication. | 0.699 |
APQ12 | YPR071W | YIL040W | YPR071W | Nuclear envelope/ER integral membrane protein; interacts and functions with Brr6p and Brl1p in lipid homeostasis; mutants are defective in nuclear pore complex biogenesis, nuclear envelope morphology, mRNA export from the nucleus and are sensitive to sterol biosynthesis inhibitors and membrane fluidizing agents; exhibits synthetic lethal genetic interactions with genes involved in lipid metabolism; Belongs to the APQ12 family. | Putative membrane protein; YPR071W is not an essential gene; YPR071W has a paralog, YIL029C, that arose from a single-locus duplication. | 0.443 |
APQ12 | YPR114W | YIL040W | YPR114W | Nuclear envelope/ER integral membrane protein; interacts and functions with Brr6p and Brl1p in lipid homeostasis; mutants are defective in nuclear pore complex biogenesis, nuclear envelope morphology, mRNA export from the nucleus and are sensitive to sterol biosynthesis inhibitors and membrane fluidizing agents; exhibits synthetic lethal genetic interactions with genes involved in lipid metabolism; Belongs to the APQ12 family. | Uncharacterized TLC domain-containing protein YPR114W; Putative protein of unknown function. | 0.514 |
BBP1 | YPR071W | YPL255W | YPR071W | Protein required for the spindle pole body (SPB) duplication; localizes at the cytoplasmic side of the central plaque periphery of the SPB; forms a complex with a nuclear envelope protein Mps2p and SPB components Spc29p and Kar1p; required for mitotic functions of Cdc5p; Belongs to the BBP1 family. | Putative membrane protein; YPR071W is not an essential gene; YPR071W has a paralog, YIL029C, that arose from a single-locus duplication. | 0.446 |
BBP1 | YPR114W | YPL255W | YPR114W | Protein required for the spindle pole body (SPB) duplication; localizes at the cytoplasmic side of the central plaque periphery of the SPB; forms a complex with a nuclear envelope protein Mps2p and SPB components Spc29p and Kar1p; required for mitotic functions of Cdc5p; Belongs to the BBP1 family. | Uncharacterized TLC domain-containing protein YPR114W; Putative protein of unknown function. | 0.480 |
IRC10 | ABM1 | YOL015W | YJR108W | Uncharacterized protein IRC10; Protein of unknown function; subunit of the leading edge protein (LEP) complex (Ssp1-Ady3-Don1-Irc10) that forms a ring-like structure at the leading edge of the prospore membrane during meiosis II; null mutant displays increased levels of spontaneous Rad52p foci. | Aberrant microtubules protein 1; Protein of unknown function; required for normal microtubule organization. | 0.603 |
IRC10 | YPR071W | YOL015W | YPR071W | Uncharacterized protein IRC10; Protein of unknown function; subunit of the leading edge protein (LEP) complex (Ssp1-Ady3-Don1-Irc10) that forms a ring-like structure at the leading edge of the prospore membrane during meiosis II; null mutant displays increased levels of spontaneous Rad52p foci. | Putative membrane protein; YPR071W is not an essential gene; YPR071W has a paralog, YIL029C, that arose from a single-locus duplication. | 0.630 |
SSS1 | YDL121C | YDR086C | YDL121C | Protein transport protein SSS1; Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p); this complex forms a channel for passage of secretory proteins through the endoplasmic reticulum membrane, and of the Ssh1p complex (Ssh1p-Sbh2p-Sss1p); interacts with Ost4p and Wbp1p; Belongs to the SecE/SEC61-gamma family. | ER export of PMA1 protein 1; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YDL121C is not an essential protein. | 0.493 |
SSS1 | YPR071W | YDR086C | YPR071W | Protein transport protein SSS1; Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p); this complex forms a channel for passage of secretory proteins through the endoplasmic reticulum membrane, and of the Ssh1p complex (Ssh1p-Sbh2p-Sss1p); interacts with Ost4p and Wbp1p; Belongs to the SecE/SEC61-gamma family. | Putative membrane protein; YPR071W is not an essential gene; YPR071W has a paralog, YIL029C, that arose from a single-locus duplication. | 0.457 |
TRE1 | YPR071W | YPL176C | YPR071W | Uncharacterized protein TRE1; Transferrin receptor-like protein; plasma membrane protein that binds Bsd2p and regulates ubiquitination and vacuolar degradation of the metal transporter Smf1p; functionally redundant with Tre2p; TRE1 has a paralog, TRE2, that arose from the whole genome duplication. | Putative membrane protein; YPR071W is not an essential gene; YPR071W has a paralog, YIL029C, that arose from a single-locus duplication. | 0.459 |
YDL121C | SSS1 | YDL121C | YDR086C | ER export of PMA1 protein 1; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YDL121C is not an essential protein. | Protein transport protein SSS1; Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p); this complex forms a channel for passage of secretory proteins through the endoplasmic reticulum membrane, and of the Ssh1p complex (Ssh1p-Sbh2p-Sss1p); interacts with Ost4p and Wbp1p; Belongs to the SecE/SEC61-gamma family. | 0.493 |
YDL121C | YPR071W | YDL121C | YPR071W | ER export of PMA1 protein 1; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YDL121C is not an essential protein. | Putative membrane protein; YPR071W is not an essential gene; YPR071W has a paralog, YIL029C, that arose from a single-locus duplication. | 0.609 |
YDL121C | YPR114W | YDL121C | YPR114W | ER export of PMA1 protein 1; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YDL121C is not an essential protein. | Uncharacterized TLC domain-containing protein YPR114W; Putative protein of unknown function. | 0.698 |
YLR146W-A | ABM1 | YLR146W-A | YJR108W | Coiled-coil domain-containing protein YLR146W-A; Putative protein of unknown function. | Aberrant microtubules protein 1; Protein of unknown function; required for normal microtubule organization. | 0.460 |
YLR146W-A | YPR071W | YLR146W-A | YPR071W | Coiled-coil domain-containing protein YLR146W-A; Putative protein of unknown function. | Putative membrane protein; YPR071W is not an essential gene; YPR071W has a paralog, YIL029C, that arose from a single-locus duplication. | 0.510 |
YPR071W | ABM1 | YPR071W | YJR108W | Putative membrane protein; YPR071W is not an essential gene; YPR071W has a paralog, YIL029C, that arose from a single-locus duplication. | Aberrant microtubules protein 1; Protein of unknown function; required for normal microtubule organization. | 0.699 |
YPR071W | APQ12 | YPR071W | YIL040W | Putative membrane protein; YPR071W is not an essential gene; YPR071W has a paralog, YIL029C, that arose from a single-locus duplication. | Nuclear envelope/ER integral membrane protein; interacts and functions with Brr6p and Brl1p in lipid homeostasis; mutants are defective in nuclear pore complex biogenesis, nuclear envelope morphology, mRNA export from the nucleus and are sensitive to sterol biosynthesis inhibitors and membrane fluidizing agents; exhibits synthetic lethal genetic interactions with genes involved in lipid metabolism; Belongs to the APQ12 family. | 0.443 |
YPR071W | BBP1 | YPR071W | YPL255W | Putative membrane protein; YPR071W is not an essential gene; YPR071W has a paralog, YIL029C, that arose from a single-locus duplication. | Protein required for the spindle pole body (SPB) duplication; localizes at the cytoplasmic side of the central plaque periphery of the SPB; forms a complex with a nuclear envelope protein Mps2p and SPB components Spc29p and Kar1p; required for mitotic functions of Cdc5p; Belongs to the BBP1 family. | 0.446 |