node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABM1 | IRC10 | YJR108W | YOL015W | Aberrant microtubules protein 1; Protein of unknown function; required for normal microtubule organization | Uncharacterized protein IRC10; Protein of unknown function; subunit of the leading edge protein (LEP) complex (Ssp1-Ady3-Don1-Irc10) that forms a ring-like structure at the leading edge of the prospore membrane during meiosis II; null mutant displays increased levels of spontaneous Rad52p foci | 0.711 |
ABM1 | YLR146W-A | YJR108W | YLR146W-A | Aberrant microtubules protein 1; Protein of unknown function; required for normal microtubule organization | Coiled-coil domain-containing protein YLR146W-A; Putative protein of unknown function | 0.566 |
ABM1 | YPR071W | YJR108W | YPR071W | Aberrant microtubules protein 1; Protein of unknown function; required for normal microtubule organization | Putative membrane protein; YPR071W is not an essential gene; YPR071W has a paralog, YIL029C, that arose from a single-locus duplication | 0.813 |
BSC4 | YLR146W-A | YNL269W | YLR146W-A | Bypass of stop codon protein 4; Protein of unknown function; protein-coding gene that evolved de novo via a series of point mutations in noncoding sequence; ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression; readthrough is increased upon depletion of Sup35p; may be involved in DNA repair pathway during stationary phase and contribute to robustness of cells when shifted to a nutrient-poor environment | Coiled-coil domain-containing protein YLR146W-A; Putative protein of unknown function | 0.454 |
BSC4 | YPR071W | YNL269W | YPR071W | Bypass of stop codon protein 4; Protein of unknown function; protein-coding gene that evolved de novo via a series of point mutations in noncoding sequence; ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression; readthrough is increased upon depletion of Sup35p; may be involved in DNA repair pathway during stationary phase and contribute to robustness of cells when shifted to a nutrient-poor environment | Putative membrane protein; YPR071W is not an essential gene; YPR071W has a paralog, YIL029C, that arose from a single-locus duplication | 0.452 |
DIA3 | YLR146W-A | YDL024C | YLR146W-A | Probable acid phosphatase DIA3; Protein of unknown function; involved in invasive and pseudohyphal growth | Coiled-coil domain-containing protein YLR146W-A; Putative protein of unknown function | 0.485 |
DIA3 | YPR071W | YDL024C | YPR071W | Probable acid phosphatase DIA3; Protein of unknown function; involved in invasive and pseudohyphal growth | Putative membrane protein; YPR071W is not an essential gene; YPR071W has a paralog, YIL029C, that arose from a single-locus duplication | 0.482 |
ECM23 | YLR146W-A | YPL021W | YLR146W-A | Non-essential protein of unconfirmed function; affects pre-rRNA processing, may act as a negative regulator of the transcription of genes involved in pseudohyphal growth; homologous to Srd1p | Coiled-coil domain-containing protein YLR146W-A; Putative protein of unknown function | 0.480 |
ECM23 | YPR071W | YPL021W | YPR071W | Non-essential protein of unconfirmed function; affects pre-rRNA processing, may act as a negative regulator of the transcription of genes involved in pseudohyphal growth; homologous to Srd1p | Putative membrane protein; YPR071W is not an essential gene; YPR071W has a paralog, YIL029C, that arose from a single-locus duplication | 0.453 |
ENV11 | YLR146W-A | YGR071C | YLR146W-A | Late endosome and vacuole interface protein 11; Protein proposed to be involved in vacuolar functions; mutant shows defect in CPY processing and fragmented vacuoles; deletion mutant has increased glycogen accumulation and displays elongated buds; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; ENV11 has a paralog, VID22, that arose from the whole genome duplication | Coiled-coil domain-containing protein YLR146W-A; Putative protein of unknown function | 0.525 |
ENV11 | YPR071W | YGR071C | YPR071W | Late endosome and vacuole interface protein 11; Protein proposed to be involved in vacuolar functions; mutant shows defect in CPY processing and fragmented vacuoles; deletion mutant has increased glycogen accumulation and displays elongated buds; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; ENV11 has a paralog, VID22, that arose from the whole genome duplication | Putative membrane protein; YPR071W is not an essential gene; YPR071W has a paralog, YIL029C, that arose from a single-locus duplication | 0.521 |
IRC10 | ABM1 | YOL015W | YJR108W | Uncharacterized protein IRC10; Protein of unknown function; subunit of the leading edge protein (LEP) complex (Ssp1-Ady3-Don1-Irc10) that forms a ring-like structure at the leading edge of the prospore membrane during meiosis II; null mutant displays increased levels of spontaneous Rad52p foci | Aberrant microtubules protein 1; Protein of unknown function; required for normal microtubule organization | 0.711 |
IRC10 | YLR146W-A | YOL015W | YLR146W-A | Uncharacterized protein IRC10; Protein of unknown function; subunit of the leading edge protein (LEP) complex (Ssp1-Ady3-Don1-Irc10) that forms a ring-like structure at the leading edge of the prospore membrane during meiosis II; null mutant displays increased levels of spontaneous Rad52p foci | Coiled-coil domain-containing protein YLR146W-A; Putative protein of unknown function | 0.454 |
IRC10 | YPR071W | YOL015W | YPR071W | Uncharacterized protein IRC10; Protein of unknown function; subunit of the leading edge protein (LEP) complex (Ssp1-Ady3-Don1-Irc10) that forms a ring-like structure at the leading edge of the prospore membrane during meiosis II; null mutant displays increased levels of spontaneous Rad52p foci | Putative membrane protein; YPR071W is not an essential gene; YPR071W has a paralog, YIL029C, that arose from a single-locus duplication | 0.760 |
PAU17 | PAU2 | YLL025W | YEL049W | Seripauperin-17; Protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions; SWAT-GFP and mCherry fusion proteins localize to the vacuole; YLL025W is not an essential gene; Belongs to the SRP1/TIP1 family. Seripauperin subfamily | Seripauperin-2; Member of the seripauperin multigene family; encoded mainly in subtelomeric region; active during alcoholic fermentation; regulated by anaerobiosis; negatively regulated by oxygen; repressed by heme | 0.915 |
PAU17 | YLR146W-A | YLL025W | YLR146W-A | Seripauperin-17; Protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions; SWAT-GFP and mCherry fusion proteins localize to the vacuole; YLL025W is not an essential gene; Belongs to the SRP1/TIP1 family. Seripauperin subfamily | Coiled-coil domain-containing protein YLR146W-A; Putative protein of unknown function | 0.522 |
PAU17 | YPR071W | YLL025W | YPR071W | Seripauperin-17; Protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions; SWAT-GFP and mCherry fusion proteins localize to the vacuole; YLL025W is not an essential gene; Belongs to the SRP1/TIP1 family. Seripauperin subfamily | Putative membrane protein; YPR071W is not an essential gene; YPR071W has a paralog, YIL029C, that arose from a single-locus duplication | 0.499 |
PAU2 | PAU17 | YEL049W | YLL025W | Seripauperin-2; Member of the seripauperin multigene family; encoded mainly in subtelomeric region; active during alcoholic fermentation; regulated by anaerobiosis; negatively regulated by oxygen; repressed by heme | Seripauperin-17; Protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions; SWAT-GFP and mCherry fusion proteins localize to the vacuole; YLL025W is not an essential gene; Belongs to the SRP1/TIP1 family. Seripauperin subfamily | 0.915 |
PAU2 | YLR146W-A | YEL049W | YLR146W-A | Seripauperin-2; Member of the seripauperin multigene family; encoded mainly in subtelomeric region; active during alcoholic fermentation; regulated by anaerobiosis; negatively regulated by oxygen; repressed by heme | Coiled-coil domain-containing protein YLR146W-A; Putative protein of unknown function | 0.452 |
PAU2 | YPR071W | YEL049W | YPR071W | Seripauperin-2; Member of the seripauperin multigene family; encoded mainly in subtelomeric region; active during alcoholic fermentation; regulated by anaerobiosis; negatively regulated by oxygen; repressed by heme | Putative membrane protein; YPR071W is not an essential gene; YPR071W has a paralog, YIL029C, that arose from a single-locus duplication | 0.450 |